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Dataflow programming is a popular and convenient programming paradigm in systems modelling, optimisation, and machine learning. It has a number of advantages, for instance the lacks of control flow allows computation to be carried out in…

Programming Languages · Computer Science 2021-03-03 Steven W. T. Cheung , Dan R. Ghica , Koko Muroya

We describe a scalable database cluster for the spatial analysis and annotation of high-throughput brain imaging data, initially for 3-d electron microscopy image stacks, but for time-series and multi-channel data as well. The system was…

Contextual Partitioning introduces an innovative approach to enhancing the architectural design of large-scale computational models through the dynamic segmentation of parameters into context-aware regions. This methodology emphasizes the…

Computation and Language · Computer Science 2025-08-11 Offa Kingsleigh , Alfred Abercrombie , David Woolstencroft , Beorhtric Meadowcroft , Marcus Irvin

The advent of modern data processing has led to an increasing tendency towards interdisciplinarity, which frequently involves the importation of different technical approaches. Consequently, there is an urgent need for a unified data…

Machine Learning · Computer Science 2024-06-04 Chen Zhang , Lecheng Jia , Wei Zhang , Ning Wen

We propose the Financial Connectome, a new scientific discipline that models financial markets through the lens of brain functional architecture. Inspired by the foundational work of group independent component analysis (groupICA) in…

Computational Finance · Quantitative Finance 2026-03-24 Yuda Bi , Vince D Calhoun

We present a multi-scale differentiable brain modeling workflow utilizing BrainPy, a unique differentiable brain simulator that combines accurate brain simulation with powerful gradient-based optimization. We leverage this capability of…

Neural and Evolutionary Computing · Computer Science 2024-09-26 Chaoming Wang , Muyang Lyu , Tianqiu Zhang , Sichao He , Si Wu

Network control theory has recently emerged as a promising approach for understanding brain function and dynamics. By operationalizing notions of control theory for brain networks, it offers a fundamental explanation for how brain dynamics…

Quantitative Methods · Quantitative Biology 2020-03-20 Shikuang Deng , Shi Gu

The differentiable programming paradigm is a cornerstone of modern scientific computing. It refers to numerical methods for computing the gradient of a numerical model's output. Many scientific models are based on differential equations,…

Functional connectivity is a key approach to investigate oscillatory activities of the brain that provides important insights on the underlying dynamic of neuronal interactions and that is mostly applied for brain activity analysis.…

Neurons and Cognition · Quantitative Biology 2022-02-17 Marie-Constance Corsi , Sylvain Chevallier , Fabrizio De Vico Fallani , Florian Yger

Recently, there have been several concerted international efforts - the BRAIN initiative, European Human Brain Project and the Human Connectome Project, to name a few - that hope to revolutionize our understanding of the connected brain.…

Neurons and Cognition · Quantitative Biology 2016-02-10 Adeel Razi , Karl Friston

Electron microscopic connectomics is an ambitious research direction with the goal of studying comprehensive brain connectivity maps by using high-throughput, nano-scale microscopy. One of the main challenges in connectomics research is…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Tran Minh Quan , David G. C. Hildebrand , Won-Ki Jeong

To understand the biological characteristics of neurological disorders with functional connectivity (FC), recent studies have widely utilized deep learning-based models to identify the disease and conducted post-hoc analyses via explainable…

Machine Learning · Computer Science 2023-10-09 Eunsong Kang , Da-woon Heo , Jiwon Lee , Heung-Il Suk

The field of declarative stream programming (discrete time, clocked synchronous, modular, data-centric) is divided between the data-flow graph paradigm favored by domain experts, and the functional reactive paradigm favored by academics. In…

Programming Languages · Computer Science 2014-06-10 Baltasar Trancón y Widemann , Markus Lepper

The brain is a highly complex organ consisting of a myriad of subsystems that flexibly interact and adapt over time and context to enable perception, cognition, and behavior. Understanding the multi-scale nature of the brain, i.e., how…

Neurons and Cognition · Quantitative Biology 2025-01-17 Adam S. Charles

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neurons and Cognition · Quantitative Biology 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

The characterisation of the brain as a "connectome", in which the connections are represented by correlational values across timeseries and as summary measures derived from graph theory analyses, has been very popular in the last years.…

Machine Learning · Computer Science 2020-03-13 Tiago Azevedo , Luca Passamonti , Pietro Liò , Nicola Toschi

More often than not, there is a need to understand the structure of complex computer code: what functions and in what order they are called, how information travels around static, input, and output variables, what depends on what. As a…

Software Engineering · Computer Science 2016-10-10 Igor Polkovnikov

Connectomes are spatially embedded networks whose architecture has been shaped by physical constraints and communication needs throughout evolution. Using a decentralized navigation protocol, we investigate the relationship between the…

Neurons and Cognition · Quantitative Biology 2020-02-07 Antoine Allard , M. Ángeles Serrano

The differentiable implementation of logic yields a seamless combination of symbolic reasoning and deep neural networks. Recent research, which has developed a differentiable framework to learn logic programs from examples, can even acquire…

Artificial Intelligence · Computer Science 2021-03-03 Hikaru Shindo , Masaaki Nishino , Akihiro Yamamoto

We propose Differentiable Window, a new neural module and general purpose component for dynamic window selection. While universally applicable, we demonstrate a compelling use case of utilizing Differentiable Window to improve standard…

Machine Learning · Computer Science 2020-06-25 Thanh-Tung Nguyen , Xuan-Phi Nguyen , Shafiq Joty , Xiaoli Li