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The purpose of this paper is to study optimality of circular neighbor-balanced block designs when neighbor effects are present in the model. In the literature many optimality results are established for direct effects and neighbor effects…

Statistics Theory · Mathematics 2007-06-13 R. A. Bailey , P. Druilhet

The interference model has been widely used and studied in block experiments where the treatment for a particular plot has effects on its neighbor plots. In this paper, we study optimal circular designs for the proportional interference…

Statistics Theory · Mathematics 2015-07-31 Kang Li , Wei Zheng , Mingyao Ai

We propose a method for constructing optimal block designs for experiments on networks. The response model for a given network interference structure extends the linear network effects model to incorporate blocks. The optimality criteria…

Methodology · Statistics 2019-11-26 Vasiliki Koutra , Steven G. Gilmour , Ben M. Parker

Optimal block designs in small blocks are explored when the treatments have a natural ordering and interest lies in comparing consecutive pairs of treatments. We first develop an approximate theory which leads to a convenient multiplicative…

Statistics Theory · Mathematics 2014-05-20 S. Huda , Rahul Mukerjee

We consider experiments for comparing treatments using units that are ordered linearly over time or space within blocks. In addition to the block effect, we assume that a trend effect influences the response. The latter is modeled as a…

Statistics Theory · Mathematics 2008-12-18 Dibyen Majumdar , John Stufken

There have been some major advances in the theory of optimal designs for interference models. However, the majority of them focus on one-dimensional layout of the block and the study for two-dimensional interference model is quite limited…

Methodology · Statistics 2017-05-24 A. S. Hedayat , Heng Xu , Wei Zheng

We propose a novel model-based approach for constructing optimal designs with complex blocking structures and network effects, for application in agricultural field experiments. The potential interference among treatments applied to…

Methodology · Statistics 2021-08-25 Vasiliki Koutra , Steven G. Gilmour , Ben M. Parker , Andrew Mead

Suppose that we intend to perform an experiment consisting of a set of independent trials. The mean value of the response of each trial is assumed to be equal to the sum of the effect of the treatment selected for the trial, and some…

Statistics Theory · Mathematics 2016-12-21 Samuel Rosa , Radoslav Harman

We consider a potential outcomes model in which interference may be present between any two units but the extent of interference diminishes with spatial distance. The causal estimand is the global average treatment effect, which compares…

Methodology · Statistics 2022-09-16 Michael P. Leung

For experiments running in field plots or over time, the observations are often correlated due to spatial or serial correlation, which leads to correlated errors in a linear model analyzing the treatment means. Without knowing the exact…

Methodology · Statistics 2016-05-30 Rena K. Mann , Roderick Edwards , Julie Zhou

A systematic study is carried out regarding universally optimal designs under the interference model, previously investigated by Kunert and Martin [Ann. Statist. 28 (2000) 1728-1742] and Kunert and Mersmann [J. Statist. Plann. Inference 141…

Statistics Theory · Mathematics 2015-04-06 Wei Zheng

The conclusions of randomized controlled trials may be biased when the outcome of one unit depends on the treatment status of other units, a problem known as interference. In this work, we study interference in the setting of one-sided…

Methodology · Statistics 2022-11-01 Jennifer Brennan , Vahab Mirrokni , Jean Pouget-Abadie

Hierarchical random effect models are used for different purposes in clinical research and other areas. In general, the main focus is on population parameters related to the expected treatment effects or group differences among all units of…

Applications · Statistics 2021-04-07 Maryna Prus , Norbert Benda , Rainer Schwabe

Blocking is often used to reduce known variability in designed experiments by collecting together homogeneous experimental units. A common modelling assumption for such experiments is that responses from units within a block are dependent.…

Methodology · Statistics 2018-11-07 W. G. Mueller , A. Rappold , D. C. Woods

Estimating the effects of interventions in networks is complicated when the units are interacting, such that the outcomes for one unit may depend on the treatment assignment and behavior of many or all other units (i.e., there is…

Methodology · Statistics 2014-08-15 Dean Eckles , Brian Karrer , Johan Ugander

We investigate block designs, under the A- and MV-criteria, when each treatment can have only one or two replications due to resource constraints, as can happen, for example, in early generation varietal trials. While these are commonly…

Statistics Theory · Mathematics 2026-03-25 R. A. Bailey , Rahul Mukerjee

Approximate circuits trading the power consumption for the quality of results play a key role in the development of energy-aware systems. Designing complex approximate circuits is, however, a very difficult and computationally demanding…

Hardware Architecture · Computer Science 2025-10-23 Milan Češka , Jiří Matyáš , Vojtech Mrazek , Tomáš Vojnar

To minimize the mean squared error (MSE) in global average treatment effect (GATE) estimation under network interference, a popular approach is to use a cluster-randomized design. However, in the presence of homophily, which is common in…

(Block-)coordinate minimization is an iterative optimization method which in every iteration finds a global minimum of the objective over a variable or a subset of variables, while keeping the remaining variables constant. While for some…

Optimization and Control · Mathematics 2019-10-22 Tomáš Werner , Daniel Průša

Researchers often turn to block randomization to increase the precision of their inference or due to practical considerations, such as in multisite trials. However, if the number of treatments under consideration is large it might not be…

Methodology · Statistics 2025-08-26 Taehyeon Koo , Nicole E. Pashley
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