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Non-invasive observation of spatiotemporal neural activity of large neural populations distributed over entire brains is a longstanding goal of neuroscience. We developed a real-time volumetric and multispectral optoacoustic tomography…

Neurons and Cognition · Quantitative Biology 2015-01-13 Gali Sela , Antonella Lauri , X. Luís Deán-Ben , Moritz Kneipp , Vasilis Ntziachristos , Shy Shoham , Gil G. Westmeyer , Daniel Razansky

The functional computation of the human brain arises from the collective behaviour of the underlying neural network. The emerging technology enables the recording of population activity in neurons, and the theory of neural networks is…

Biological Physics · Physics 2025-08-29 Yoshiaki Horiike , Shin Fujishiro

Functional magnetic resonance imaging (fMRI) has provided invaluable insight into our understanding of human behavior. However, large inter-individual differences in both brain anatomy and functional localization after anatomical alignment…

Applications · Statistics 2021-11-03 Guoqing Wang , Abhirup Datta , Martin A. Lindquist

Photoacoustic fluctuation imaging, which exploits randomness in photoacoustic generation, provides enhanced images in terms of resolution and visibility, as compared to conventional photoacoustic images. While a few experimental…

Optics · Physics 2020-11-19 Sergey Vilov , Guillaume Godefroy , Bastien Arnal , Emmanuel Bossy

High resolution transcranial ultrasound imaging in humans has been a persistent challenge for ultrasound due to the imaging degradation effects from aberration and reverberation. These mechanisms depend strongly on skull morphology and they…

Medical Physics · Physics 2018-11-28 Danai E. Soulioti , David Espíndola , Paul A. Dayton , Gianmarco Pinton

Task functional magnetic resonance imaging (fMRI) is a type of neuroimaging data used to identify areas of the brain that activate during specific tasks or stimuli. These data are conventionally modeled using a massive univariate approach…

Methodology · Statistics 2022-11-04 Daniel A. Spencer , David Bolin , Amanda F. Mejia

One of the challenges in functional brain imaging is integration of complementary imaging modalities, such as magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI). MEG, which uses highly sensitive superconducting…

During brain tumour resection, localising cancerous tissue and delineating healthy and pathological borders is challenging, even for experienced neurosurgeons and neuroradiologists. Intraoperative imaging is commonly employed for…

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

Applications · Statistics 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

Brain-mapping techniques have proven to be vital in understanding the molecular, cellular, and functional mechanisms of the brain. Normal anatomical imaging can provide structural information on certain abnormalities in the brain. However…

Emerging Technologies · Computer Science 2013-01-03 Nivedita Daimiwal , M. Sundhararajan , Revati Shriram

To understand Working of Human Brain measurements related to the brain function are required. These measurements should be possibly non-invasive. Brain should be disturbed as less as possible during the measurement. Integration of various…

Emerging Technologies · Computer Science 2015-06-16 Revati Shriram , M. Sundhararajan , Nivedita Daimiwal

A fundamental challenge in neuroscience is to decode mental states from brain activity. While functional magnetic resonance imaging (fMRI) offers a non-invasive approach to capture brain-wide neural dynamics with high spatial precision,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-31 Yueh-Po Peng , Vincent K. M. Cheung , Li Su

To learn how cognition is implemented in the brain, we must build computational models that can perform cognitive tasks, and test such models with brain and behavioral experiments. Cognitive science has developed computational models of…

Neurons and Cognition · Quantitative Biology 2018-08-01 Nikolaus Kriegeskorte , Pamela K. Douglas

Skull-stripping separates the skull region of the head from the soft brain tissues. In many cases of brain image analysis, this is an essential preprocessing step in order to improve the final result. This is true for both registration and…

Computer Vision and Pattern Recognition · Computer Science 2012-04-03 Stefan Bauer , Lutz-P. Nolte , Mauricio Reyes

Current advances in neurosciences deal with the functional architecture of the central nervous system, paving the way for holistic theories that improve our understanding of brain activity. From topology, a strong concept comes into play in…

Neurons and Cognition · Quantitative Biology 2015-12-02 A. Tozzi , J. F. Peters

Neuronal electrical activity underlies human cognition including perception, attention, memory, language, and decision-making. Yet its direct, noninvasive measurement in the living human brain remains a fundamental challenge. Existing…

Visual reconstruction algorithms are an interpretive tool that map brain activity to pixels. Past reconstruction algorithms employed brute-force search through a massive library to select candidate images that, when passed through an…

Neurons and Cognition · Quantitative Biology 2023-05-03 Reese Kneeland , Jordyn Ojeda , Ghislain St-Yves , Thomas Naselaris

Neuroradiologists and neurosurgeons increasingly opt to use functional magnetic resonance imaging (fMRI) to map functionally relevant brain regions for noninvasive presurgical planning and intraoperative neuronavigation. This application…

Methodology · Statistics 2023-06-07 Andrew S. Whiteman , Andreas J. Bartsch , Jian Kang , Timothy D. Johnson

Photoacoustic tomography (PAT) is a novel and rapidly promising technique in the field of medical imaging, based on the generation of acoustic waves inside an object of interest by stimulating non-ionizing laser pulses. This acoustic wave…

Analysis of PDEs · Mathematics 2022-02-08 Hyungyeong Jung , Sunghwan Moon

Brain decoding is a field of computational neuroscience that uses measurable brain activity to infer mental states or internal representations of perceptual inputs. Therefore, we propose a novel approach to brain decoding that also relies…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Matteo Ferrante , Tommaso Boccato , Nicola Toschi