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The development of tissue-engineered cardiovascular implants can improve the lives of large segments of our society who suffer from cardiovascular diseases. Regenerative tissues are fabricated using a process called tissue maturation.…

Computational Engineering, Finance, and Science · Computer Science 2025-03-24 Mahmoud Sesa , Hagen Holthusen , Lukas Lamm , Christian Böhm , Tim Brepols , Stefan Jockenhövel , Stefanie Reese

Percutaneous needle insertions are commonly performed for diagnostic and therapeutic purposes as an effective alternative to more invasive surgical procedures. However, the outcome of needle-based approaches relies heavily on the accuracy…

Robotics · Computer Science 2023-12-01 Yanzhou Wang , Lidia Al-Zogbi , Guanyun Liu , Jiawei Liu , Junichi Tokuda , Axel Krieger , Iulian Iordachita

In tissue engineering, 3D scaffolds and chemical treatments are often used for providing a cell-friendly surface for improving cell adhesion and tissue growth. Indeed, the cell adhesion degree can be controlled by physical-chemical changes…

The ability of mechanical systems to perform basic computations has gained traction over recent years, providing an unconventional alternative to digital computing in off grid, low power, and severe environments which render the majority of…

Applied Physics · Physics 2024-05-13 M. Moghaddaszadeh , M. Mousa , A. Aref , M. Nouh

The rapid proliferation of Deep Learning is increasingly constrained by its heavy reliance on high-performance hardware, particularly Graphics Processing Units (GPUs). These specialized accelerators are not only prohibitively expensive and…

Machine Learning · Computer Science 2026-01-06 Emrah Mete , Emin Erkan Korkmaz

Thick honeycomb-like electrospun scaffold with nanoparticles of hydroxyapatite (nHA) recently demonstrated its potential to promote proliferation and differentiation of a murine embryonic cell line (C3H10T1/2) to osteoblasts. In order to…

This study presents a comprehensive examination of the development of TiN/SiO$_\mathrm{x}$/Cu/SiO$_\mathrm{x}$/TiN memristive devices, engineered for neuromorphic applications using a wedge-type deposition technique and Monte Carlo…

Mesoscale and Nanoscale Physics · Physics 2024-06-28 Rouven Lamprecht , Luca Vialetto , Tobias Gergs , Finn Zahari , Richard Marquardt , Jan Trieschmann , Hermann Kohlstedt

Nature evolves structures like honeycombs at optimized performance with limited material. These efficient structures can be artificially created with the collaboration of structural topology optimization and additive manufacturing. However,…

Computational Engineering, Finance, and Science · Computer Science 2023-03-22 Shengze Zhong , Parinya Punpongsanon , Daisuke Iwai , Kosuke Sato

Fluid flow and mass transfer inside a bioreactor play a pivotal role in growing bone grafts, as cell proliferation is limited by the transport of nutrients and oxygen, as well as the removal of by-products from cells within the scaffold.…

Biological Physics · Physics 2025-01-09 Mohammad Osaid , Debabrata Dasgupta

In this work, we explore the various Brain Neuron tracking techniques, which is one of the most significant applications of Diffusion Tensor Imaging. Tractography provides us with a non-invasive method to analyze underlying tissue…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Nandakishore Puttashamachar , Ulas Bagci

The mathematical model underlying the Neural Engineering Framework (NEF) expresses neuronal input as a linear combination of synaptic currents. However, in biology, synapses are not perfect current sources and are thus nonlinear. Detailed…

Neurons and Cognition · Quantitative Biology 2017-10-24 Andreas Stöckel , Aaron R. Voelker , Chris Eliasmith

Deep neural networks (DNNs) transform stimuli across multiple processing stages to produce representations that can be used to solve complex tasks, such as object recognition in images. However, a full understanding of how they achieve this…

Neurons and Cognition · Quantitative Biology 2018-11-01 David G. T. Barrett , Ari S. Morcos , Jakob H. Macke

Neuromorphic engineering makes use of mixed-signal analog and digital circuits to directly emulate the computational principles of biological brains. Such electronic systems offer a high degree of adaptability, robustness, and energy…

Systems and Control · Electrical Eng. & Systems 2026-04-09 Loris Mendolia , Chenxi Wen , Elisabetta Chicca , Giacomo Indiveri , Rodolphe Sepulchre , Jean-Michel Redouté , Alessio Franci

Neurological disorders pose major global health challenges, driving advances in brain signal analysis. Scalp electroencephalography (EEG) and intracranial EEG (iEEG) are widely used for diagnosis and monitoring. However, dataset…

Neurons and Cognition · Quantitative Biology 2025-10-24 Jiahe Li , Xin Chen , Fanqi Shen , Junru Chen , Yuxin Liu , Daoze Zhang , Zhizhang Yuan , Fang Zhao , Meng Li , Yang Yang

A complexity-theoretic approach to studying biological networks is proposed. A simple graph representation is used where molecules (DNA, RNA, proteins and chemicals) are vertices and relations between them are directed and signed…

Social and Information Networks · Computer Science 2018-04-25 Ali Atiia , François Major , Jérôme Waldispühl

Mechanistic modeling provides a biophysically grounded framework for studying the spread of pathological tau protein in tauopathies like Alzheimer's disease. Existing approaches typically model tau propagation as a diffusive process on the…

Computational Engineering, Finance, and Science · Computer Science 2026-03-18 Nuutti Barron , Heng Rao , Urmi Saha , Yu Gu , Zhenghao Liu , Ge Yu , Defu Yang , Ashish Raj , Minghan Chen

Despite existing 3D cloth simulators producing realistic results, they predominantly operate on discrete surface representations (e.g. points and meshes) with a fixed spatial resolution, which often leads to large memory consumption and…

Graphics · Computer Science 2024-11-08 Navami Kairanda , Marc Habermann , Christian Theobalt , Vladislav Golyanik

With many fantastic properties, memristive devices have been proposed as top candidate for next-generation memory and neuromorphic computing chips. Significant research progresses have been made in improving performance of individual…

Applied Physics · Physics 2019-12-23 Chen-Yu Wang , Cong Wang , Fanhao Meng , Pengfei Wang , Shuang Wang , Shi-Jun Liang , Feng Miao

Reconstructing complex 3D interfaces from indirect measurements remains a grand challenge in scientific computing, particularly for ill-posed inverse problems like Electrical Impedance Tomography (EIT). Traditional shape optimization…

Numerical Analysis · Mathematics 2026-04-23 Haibo Liu , Junqing Chen , Guang Lin

Neural Networks (NN) provide a solid and reliable way of executing different types of applications, ranging from speech recognition to medical diagnosis, speeding up onerous and long workloads. The challenges involved in their…

Hardware Architecture · Computer Science 2023-09-26 Federico Manca , Francesco Ratto
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