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We introduce and train distributed neural architectures (DNA) in vision and language domains. DNAs are initialized with a proto-architecture that consists of (transformer, MLP, attention, etc.) modules and routers. Any token (or patch) can…

Machine Learning · Computer Science 2025-06-30 Aditya Cowsik , Tianyu He , Andrey Gromov

DNA storage has emerged as an important area of research. The reliability of DNA storage system depends on designing the DNA strings (called DNA codes) that are sufficiently dissimilar. In this work, we introduce DNA codes that satisfy a…

Information Theory · Computer Science 2022-11-28 Krishna Gopal Benerjee , Sourav Deb , Manish K Gupta

DNA sequence analysis is fundamental to life science research. The rapid development of next generation sequencing (NGS) technologies, and the richness and diversity of applications it makes feasible, have created an enormous gulf between…

Computational Engineering, Finance, and Science · Computer Science 2013-10-29 Shel Swenson , Yogesh Simmhan , Viktor Prasanna , Manish Parashar , Jason Riedy , David Bader , Richard Vuduc

A critical step of genome sequence analysis is the mapping of sequenced DNA fragments (i.e., reads) collected from an individual to a known linear reference genome sequence (i.e., sequence-to-sequence mapping). Recent works replace the…

DNA microarrays are a relatively new technology that can simultaneously measure the expression level of thousands of genes. They have become an important tool for a wide variety of biological experiments. One of the most common goals of DNA…

Methodology · Statistics 2013-07-02 Eric Bair

Background Nucleotide sequences contain multiple codes responsible for organism's functioning and structure. They can be investigated by various signal processing methods. These techniques are well suited for indication of frequently…

Quantitative Methods · Quantitative Biology 2007-05-23 Simon Kogan

Addressing the growing demands of artificial intelligence (AI) and data analytics requires new computing approaches. In this paper, we propose a reconfigurable hardware accelerator designed specifically for AI and data-intensive…

Hardware Architecture · Computer Science 2026-02-05 Md Rownak Hossain Chowdhury , Mostafizur Rahman

DNA storage is a promising archival data storage solution to today's big data problem. A DNA storage system encodes and stores digital data with synthetic DNA sequences and decodes DNA sequences back to digital data via sequencing. For…

Emerging Technologies · Computer Science 2024-03-22 Yixun Wei , Wenlong Wang , Huibing Dong , Bingzhe Li , David Du

DNA labeling is a powerful tool in molecular biology and biotechnology that allows for the visualization, detection, and study of DNA at the molecular level. Under this paradigm, a DNA molecule is being labeled by specific k patterns and is…

Information Theory · Computer Science 2024-01-24 Dganit Hanania , Daniella Bar-Lev , Yevgeni Nogin , Yoav Shechtman , Eitan Yaakobi

Quantum computing provides computational advantages in various domains. To benefit from these advantages complex hybrid quantum applications must be built, which comprise both quantum and classical programs. Engineering these applications…

Motivation: Array Comparative Genomic Hybridization (aCGH) is used to scan the entire genome for variations in DNA copy number. A central task in the analysis of aCGH data is the segmentation into groups of probes sharing the same DNA copy…

Quantitative Methods · Quantitative Biology 2008-04-29 Erez Ben-Yaacov , Yonina Eldar

Deep Neural Networks (DNNs) have already become a crucial computational approach to revealing the spatial patterns in the human brain; however, there are three major shortcomings in utilizing DNNs to detect the spatial patterns in…

Machine Learning · Computer Science 2022-05-26 Wei Zhang , Yu Bao

DNA computing, a nontraditional computing mechanism, provides a feasible and effective method for solving NP-hard problems because of the vast parallelism and high-density storage of DNA molecules. Although DNA computing has been exploited…

Molecular Networks · Quantitative Biology 2022-11-17 Enqiang Zhu , Xianhang Luo , Chanjuan Liu , Xiaolong Shi , Jin Xu

Graph Neural Network (GNN) inference is used in many real-world applications. Data sparsity in GNN inference, including sparsity in the input graph and the GNN model, offer opportunities to further speed up inference. Also, many pruning…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-24 Bingyi Zhang , Viktor Prasanna

We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-29 Marquita Ellis , Giulia Guidi , Aydın Buluç , Leonid Oliker , Katherine Yelick

Convolutional Neural Networks (CNNs), a prominent type of Deep Neural Networks (DNNs), have emerged as a state-of-the-art solution for solving machine learning tasks. To improve the performance and energy efficiency of CNN inference, the…

Hardware Architecture · Computer Science 2024-08-06 Rachmad Vidya Wicaksana Putra , Muhammad Abdullah Hanif , Muhammad Shafique

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

Genomics · Quantitative Biology 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan

Spurred by widening gap between data processing speed and data communication speed in Von-Neumann computing architectures, some bioinformatic applications have harnessed the computational power of Processing-in-Memory (PIM) platforms.…

Hardware Architecture · Computer Science 2020-08-17 Shaahin Angizi , Naima Ahmed Fahmi , Wei Zhang , Deliang Fan

Regular expression matching is essential for many applications, such as finding patterns in text, exploring substrings in large DNA sequences, or lexical analysis. However, sequential regular expression matching may be time-prohibitive for…

Formal Languages and Automata Theory · Computer Science 2015-06-30 Suejb Memeti , Sabri Pllana

Harnessing the intrinsic dynamics of physical systems for information processing opens new avenues for computation embodied in matter. Using simulations of a model system, we show that assemblies of DNA tiles capable of self-organizing into…

Soft Condensed Matter · Physics 2025-10-23 Tim E. Veenstra , René van Roij , Marjolein Dijkstra