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Building predictive models for tabular data presents fundamental challenges, notably in scaling consistently, i.e., more resources translating to better performance, and generalizing systematically beyond the training data distribution.…

Interpretability of machine learning models is critical for data-driven precision medicine efforts. However, highly predictive models are generally complex and are difficult to interpret. Here using Model-Agnostic Explanations algorithm, we…

Quantitative Methods · Quantitative Biology 2016-10-31 Gajendra Jung Katuwal , Robert Chen

Experts advising decision-makers are likely to display expertise which varies as a function of the problem instance. In practice, this may lead to sub-optimal or discriminatory decisions against minority cases. In this work we model such…

Artificial Intelligence · Computer Science 2023-10-27 Axel Abels , Tom Lenaerts , Vito Trianni , Ann Nowé

In recent years, dynamically growing data and incrementally growing number of classes pose new challenges to large-scale data classification research. Most traditional methods struggle to balance the precision and computational burden when…

Machine Learning · Computer Science 2016-11-01 Tingting Xie , Yuxing Peng , Changjian Wang

Additive models, such as produced by gradient boosting, and full interaction models, such as classification and regression trees (CART), are widely used algorithms that have been investigated largely in isolation. We show that these models…

Decision-making plays a pivotal role in shaping outcomes in various disciplines, such as medicine, economics, and business. This paper provides guidance to practitioners on how to implement a decision tree designed to address treatment…

Econometrics · Economics 2024-06-05 Hugo Bodory , Federica Mascolo , Michael Lechner

Clustering serves as a vital tool for uncovering latent data structures, and achieving both high accuracy and interpretability is essential. To this end, existing methods typically construct binary decision trees by solving mixed-integer…

Machine Learning · Computer Science 2026-02-17 Hayato Suzuki , Shunnosuke Ikeda , Yuichi Takano

Machine learning has become integral to medical research and is increasingly applied in clinical settings to support diagnosis and decision-making; however, its effectiveness depends on access to large, diverse datasets, which are limited…

Machine Learning · Computer Science 2026-04-21 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

An important task in clinical medicine is the construction of risk prediction models for specific subgroups of patients based on high-dimensional molecular measurements such as gene expression data. Major objectives in modeling…

Methodology · Statistics 2020-03-23 Katrin Madjar , Jörg Rahnenführer

We propose a novel tree-based ensemble method, named XGBoostPP, to nonparametrically estimate the intensity of a point process as a function of covariates. It extends the use of gradient-boosted regression trees (Chen & Guestrin, 2016) to…

Methodology · Statistics 2024-02-01 C. Lu , Y. Guan , M. N. M. van Lieshout , G. Xu

Flexible machine learning tools are increasingly used to estimate heterogeneous treatment effects. This paper gives an accessible tutorial demonstrating the use of the causal forest algorithm, available in the R package grf. We start with a…

Applications · Statistics 2024-12-17 Erik Sverdrup , Maria Petukhova , Stefan Wager

We propose generalized random forests, a method for non-parametric statistical estimation based on random forests (Breiman, 2001) that can be used to fit any quantity of interest identified as the solution to a set of local moment…

Methodology · Statistics 2018-04-06 Susan Athey , Julie Tibshirani , Stefan Wager

Tree-based models have been successfully applied to a wide variety of tasks, including time series forecasting. They are increasingly in demand and widely accepted because of their comparatively high level of interpretability. However, many…

Machine Learning · Computer Science 2024-01-03 Matthias Jakobs , Amal Saadallah

The segmentation of individual trees from forest point clouds is a crucial task for downstream analyses such as carbon sequestration estimation. Recently, deep-learning-based methods have been proposed which show the potential of learning…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Jonathan Henrich , Jan van Delden

Clinical time series data are critical for patient monitoring and predictive modeling. These time series are typically multivariate and often comprise hundreds of heterogeneous features from different data sources. The grouping of features…

Machine Learning · Computer Science 2025-11-12 Fedor Sergeev , Manuel Burger , Polina Leshetkina , Vincent Fortuin , Gunnar Rätsch , Rita Kuznetsova

Precision oncology aims to prescribe the optimal cancer treatment to the right patients, maximizing therapeutic benefits. However, identifying patient subgroups that may benefit more from experimental cancer treatments based on randomized…

Methodology · Statistics 2026-01-06 Xingyu Li , Qing Liu , Tony Jiang , Hong Amy Xia , Peng Wei , Brian P. Hobbs

As machine learning models are increasingly deployed in sensitive application areas, the demand for interpretable and trustworthy decision-making has increased. Random Forests (RF), despite their widespread use and strong performance on…

Gradient boosting machines (GBMs) based on decision trees consistently demonstrate state-of-the-art results on regression and classification tasks with tabular data, often outperforming deep neural networks. However, these models do not…

Machine Learning · Computer Science 2023-02-23 Tristan Cinquin , Tammo Rukat , Philipp Schmidt , Martin Wistuba , Artur Bekasov

Tree ensembles are widely recognized for their effectiveness in classification tasks, achieving state-of-the-art performance across diverse domains, including bioinformatics, finance, and medical diagnosis. With increasing emphasis on data…

Machine Learning · Computer Science 2025-09-01 Ziheng Chen , Jin Huang , Jiali Cheng , Yuchan Guo , Mengjie Wang , Lalitesh Morishetti , Kaushiki Nag , Hadi Amiri

Random Forests have been one of the most popular bagging methods in the past few decades, especially due to their success at handling tabular datasets. They have been extensively studied and compared to boosting models, like XGBoost, which…

Machine Learning · Computer Science 2024-10-28 Dimitris Bertsimas , Vasiliki Stoumpou