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Skin cancer is the most common human malignancy(American Cancer Society) which is primarily diagnosed visually, starting with an initial clinical screening and followed potentially by dermoscopic(related to skin) analysis, a biopsy and…

Image and Video Processing · Electrical Eng. & Systems 2022-02-03 Kartikeya Agarwal , Tismeet Singh

Breast cancer is a relatively common cancer among gynecological cancers. Its diagnosis often relies on the pathology of cells in the lesion. The pathological diagnosis of breast cancer not only requires professionals and time, but also…

Image and Video Processing · Electrical Eng. & Systems 2024-04-15 MingXuan Xiao , Yufeng Li , Xu Yan , Min Gao , Weimin Wang

Microarray gene expression data-based tumor classification is an active and challenging issue. In this paper, an integrated tumor classification framework is presented, which aims to exploit information in existing available samples, and…

Computer Vision and Pattern Recognition · Computer Science 2019-03-01 Xiaohui Yang , Wenming Wu , Yunmei Chen , Xianqi Li , Juan Zhang , Dan Long , Lijun Yang

Cancer is a number of related yet highly heterogeneous diseases. Correct identification of cancer subtypes is critical for clinical decisions. The advance in sequencing technologies has made it possible to study cancer based on abundant…

Applications · Statistics 2018-11-27 Xiaochun Chen , Honggang Wang , Donghui Yan

Gene expression can be used to subtype breast cancer with improved prediction of risk of recurrence and treatment responsiveness over that obtained using routine immunohistochemistry (IHC). However, in the clinic, molecular profiling is…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Raktim Kumar Mondol , Ewan K. A. Millar , Peter H Graham , Lois Browne , Arcot Sowmya , Erik Meijering

According to the National Cancer Institute, there were 9.5 million cancer-related deaths in 2018. A challenge in improving treatment is resistance in genetically unstable cells. The purpose of this study is to evaluate unsupervised machine…

Genomics · Quantitative Biology 2021-08-12 Anastasia Dunca , Frederick R. Adler

Accurately identifying cancer samples is crucial for precise diagnosis and effective patient treatment. Traditional methods falter with high-dimensional and high feature-to-sample count ratios, which are critical for classifying cancer…

Machine Learning · Computer Science 2025-01-14 Tareque Mohmud Chowdhury , Farzana Tabassum , Sabrina Islam , Abu Raihan Mostofa Kamal

The work includes a brief overview of the applications of the powerful and easy-to-perform method of Microwave Radiometry (MWR) for the diagnosis of various diseases. The main goal of this paper is to develop a method for diagnosing breast…

Medical Physics · Physics 2024-02-12 Alexander V. Khoperskov , Maxim V. Polyakov

In this paper, we study the application of GIST SVM in disease prediction (detection of cancer). Pattern classification problems can be effectively solved by Support vector machines. Here we propose a classifier which can differentiate…

Machine Learning · Computer Science 2012-03-07 S. Aruna , S. P. Rajagopalan , L. V. Nandakishore

Extracting genetic information from a full range of sequencing data is important for understanding diseases. We propose a novel method to effectively explore the landscape of genetic mutations and aggregate them to predict cancer type. We…

Genomics · Quantitative Biology 2018-10-10 Zexian Zeng , Andy Vo , Chengsheng Mao , Susan E Clare , Seema A Khan , Yuan Luo

We introduce a simple, interpretable strategy for making predictions on test data when the features of the test data are available at the time of model fitting. Our proposal - customized training - clusters the data to find training points…

Applications · Statistics 2016-02-01 Scott Powers , Trevor Hastie , Robert Tibshirani

Early detection of cancers has been much explored due to its paramount importance in biomedical fields. Among different types of data used to answer this biological question, studies based on T cell receptors (TCRs) are under recent…

Machine Learning · Statistics 2022-08-10 Younghoon Kim , Tao Wang , Danyi Xiong , Xinlei Wang , Seongoh Park

Accurately predicting drug responses to cancer is an important problem hindering oncologists' efforts to find the most effective drugs to treat cancer, which is a core goal in precision medicine. The scientific community has focused on…

Machine Learning · Computer Science 2016-12-06 Turki Turki , Zhi Wei

The application of machine learning to transcriptomics data has led to significant advances in cancer research. However, the high dimensionality and complexity of RNA sequencing (RNA-seq) data pose significant challenges in pan-cancer…

Genomics · Quantitative Biology 2024-08-15 Jong Hyun Kim , Jongseong Jang

An early detection of different tumor subtypes is crucial for an effective guidance to personalized therapy. While much efforts focus on decoding the sequence of DNA basis to detect the genetic mutations related to cancer, it is becoming…

Microarray technology is known as one of the most important tools for collecting DNA expression data. This technology allows researchers to investigate and examine types of diseases and their origins. However, microarray data are often…

Quantitative Methods · Quantitative Biology 2021-01-05 Babak Nouri-Moghaddam , Mehdi Ghazanfari , Mohammad Fathian

Classification is one of the major issues in Data Mining Research fields. The classification problems in medical area often classify medical dataset based on the result of medical diagnosis or description of medical treatment by the medical…

Artificial Intelligence · Computer Science 2013-01-09 N. Kalaiselvi , H. Hannah Inbarani

Many machine learning models have been proposed to classify phenotypes from gene expression data. In addition to their good performance, these models can potentially provide some understanding of phenotypes by extracting explanations for…

Genomics · Quantitative Biology 2024-02-05 Myriam Bontonou , Anaïs Haget , Maria Boulougouri , Benjamin Audit , Pierre Borgnat , Jean-Michel Arbona

Despite the availability of large amounts of genomics data, medical treatment recommendations have not successfully used them. In this paper, we consider the utility of high dimensional genomic-clinical data and nonparametric methods for…

Methodology · Statistics 2022-02-22 Zhongyuan Chen , Ziyi Wang , Qifan Song , Jun Xie

It is highly important for governments and health organizations to monitor the prevalence of breast cancer as a leading source of cancer-related death among women. However, the accurate diagnosis of this disease is expensive, especially in…

Methodology · Statistics 2021-04-21 M. Mahdizadeha , Ehsan Zamanzade