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This article presents the first mixed-integer linear programming (MILP)-based iterative algorithm to solve factorable mixed-integer nonlinear programs (MINLPs) with bounded, differentiable periodic functions to global optimality with an…

Optimization and Control · Mathematics 2025-10-01 Christopher Montez , Sujeevraja Sanjeevi , Kaarthik Sundar

This paper proposes a Heaviside composite optimization approach and presents a progressive (mixed) integer programming (PIP) method for solving multi-class classification and multi-action treatment problems with constraints. A Heaviside…

Optimization and Control · Mathematics 2024-01-08 Yue Fang , Junyi Liu , Jong-Shi Pang

Mixed Integer programs (MIPs) are typically solved by the Branch-and-Bound algorithm. Recently, Learning to imitate fast approximations of the expert strong branching heuristic has gained attention due to its success in reducing the running…

Optimization and Control · Mathematics 2023-07-03 Sahil Manchanda , Sayan Ranu

In this paper, we develop a fast mixed-integer convex programming (MICP) framework for multi-robot navigation by combining graph attention networks and distributed optimization. We formulate a mixed-integer optimization problem for receding…

Systems and Control · Electrical Eng. & Systems 2025-03-28 Viet-Anh Le , Panagiotis Kounatidis , Andreas A. Malikopoulos

We propose a hierarchical architecture for efficiently computing high-quality solutions to structured mixed-integer programs (MIPs). To reduce computational effort, our approach decouples the original problem into a higher level problem and…

Optimization and Control · Mathematics 2025-12-04 Stefan Clarke , Bartolomeo Stellato

Network interdiction problems are combinatorial optimization problems involving two players: one aims to solve an optimization problem on a network, while the other seeks to modify the network to thwart the first player's objectives. Such…

Artificial Intelligence · Computer Science 2026-04-21 Lei Zhang , Zhiqian Chen , Chang-Tien Lu , Liang Zhao

Leveraging machine learning (ML) to predict an initial solution for mixed-integer linear programming (MILP) has gained considerable popularity in recent years. These methods predict a solution and fix a subset of variables to reduce the…

Machine Learning · Computer Science 2025-03-04 Haoyang Liu , Jie Wang , Zijie Geng , Xijun Li , Yuxuan Zong , Fangzhou Zhu , Jianye Hao , Feng Wu

Mixed-integer programming (MIP) is a well-established framework for computer-aided molecular design (CAMD). By precisely encoding the molecular space and score functions, e.g., a graph neural network, the molecular design problem is…

Computational Engineering, Finance, and Science · Computer Science 2024-11-26 Shiqiang Zhang , Christian W. Feldmann , Frederik Sandfort , Miriam Mathea , Juan S. Campos , Ruth Misener

Several recent publications report advances in training optimal decision trees (ODT) using mixed-integer programs (MIP), due to algorithmic advances in integer programming and a growing interest in addressing the inherent suboptimality of…

Machine Learning · Computer Science 2020-11-09 Haoran Zhu , Pavankumar Murali , Dzung T. Phan , Lam M. Nguyen , Jayant R. Kalagnanam

Probing in mixed-integer programming (MIP) is a technique of temporarily fixing variables to discover implications that are useful to branch-and-cut solvers. Such fixing is typically performed one variable at a time -- this paper develops…

Optimization and Control · Mathematics 2025-11-11 Yongzheng Dai , Chen Chen

Complex real-world optimization problems often involve both discrete decisions and nonlinear relationships between variables. Many such problems can be modeled as polynomial-objective integer programs, encompassing cases with quadratic and…

Neural and Evolutionary Computing · Computer Science 2026-03-23 Minshuo Li , Yaoxin Wu , Pavel Troubil , Yingqian Zhang , Wim P. M. Nuijten

Mixed-integer programming (MIP) is a powerful paradigm for modeling and solving various important combinatorial optimization problems. Recently, learning-based approaches have shown a potential to speed up MIP solving via offline training…

Artificial Intelligence · Computer Science 2025-07-24 Junyang Cai , Serdar Kadioglu , Bistra Dilkina

By exploiting the correlation between the structure and the solution of Mixed-Integer Linear Programming (MILP), Machine Learning (ML) has become a promising method for solving large-scale MILP problems. Existing ML-based MILP solvers…

Machine Learning · Computer Science 2025-01-03 Yixuan Li , Can Chen , Jiajun Li , Jiahui Duan , Xiongwei Han , Tao Zhong , Vincent Chau , Weiwei Wu , Wanyuan Wang

In this paper, we describe a novel unsupervised learning scheme for accelerating the solution of a family of mixed integer programming (MIP) problems. Distinct substantially from existing learning-to-optimize methods, our proposal seeks to…

Optimization and Control · Mathematics 2024-12-25 Shiyuan Qu , Fenglian Dong , Zhiwei Wei , Chao Shang

In fields such as autonomous and safety-critical systems, online optimization plays a crucial role in control and decision-making processes, often requiring the integration of continuous and discrete variables. These tasks are frequently…

Optimization and Control · Mathematics 2025-03-17 Marco Zamponi , Emilio Incerto , Daniele Masti , Mirco Tribastone

Recently, message-passing graph neural networks (MPNNs) have shown potential for solving combinatorial and continuous optimization problems due to their ability to capture variable-constraint interactions. While existing approaches leverage…

Artificial Intelligence · Computer Science 2025-02-05 Chendi Qian , Christopher Morris

We consider a discrete optimization formulation for learning sparse classifiers, where the outcome depends upon a linear combination of a small subset of features. Recent work has shown that mixed integer programming (MIP) can be used to…

Machine Learning · Statistics 2021-06-08 Antoine Dedieu , Hussein Hazimeh , Rahul Mazumder

We present an integrated prediction-optimization (PredOpt) framework to efficiently solve sequential decision-making problems by predicting the values of binary decision variables in an optimal solution. We address the key issues of…

Machine Learning · Computer Science 2023-11-14 Dogacan Yilmaz , İ. Esra Büyüktahtakın

Piecewise regression is a versatile approach used in various disciplines to approximate complex functions from limited, potentially noisy data points. In control, piecewise regression is, e.g., used to approximate the optimal control law of…

Optimization and Control · Mathematics 2024-07-10 Dieter Teichrib , Moritz Schulze Darup

Graph neural networks (GNNs) have emerged as a powerful tool for solving combinatorial optimization problems (COPs), exhibiting state-of-the-art performance in both graph-structured and non-graph-structured domains. However, existing…

Artificial Intelligence · Computer Science 2024-06-21 Yaochu Jin , Xueming Yan , Shiqing Liu , Xiangyu Wang