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Significance: Endoscopic screening for esophageal cancer may enable early cancer diagnosis and treatment. While optical microendoscopic technology has shown promise in improving specificity, the limited field of view (<1 mm) significantly…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Xiaohui Zhang , Mimi Tan , Mansour Nabil , Richa Shukla , Shaleen Vasavada , Sharmila Anandasabapathy , Mark A. Anastasio , Elena Petrova

We review our recent developments of near-field scanning optical microscopy (NSOM) that uses an active tip made of a single fluorescent nanodiamond (ND) grafted onto the apex of a substrate fiber tip. The ND hosting a limited number of…

Optics · Physics 2015-01-16 A. Drezet , Y. Sonnefraud , A. Cuche , O. Mollet , M. Berthel , S. Huant

We provide an experimental demonstration of a direct fiber-optic link for RF transmission ("radio-over-fiber") using a sensitive optical antenna based on a rubidium vapor cell. The scheme relies on measuring the transmission of laser light…

Atomic Physics · Physics 2018-05-29 A. B. Deb , N. Kjærgaard

Diamond containing the negatively charged nitrogen-vacancy (NV) center is emerging as a significant new system for magnetometry. However, most NV sensors require microscopes to collect the fluorescence signals and are therefore limited to…

A major open challenge in neuroscience is the ability to measure and perturb neural activity in vivo from well-defined neural sub-populations at cellular resolution anywhere in the brain. However, limitations posed by scattering and…

Biological Physics · Physics 2017-11-10 Shay Ohayon , Antonio Miguel Caravaca-Aguirre , Rafael Piestun , James J. DiCarlo

Hair-thin optical fiber endoscopes have opened up new paradigms for advanced imaging applications in vivo. In certain applications, such as optical coherence tomography (OCT), light-shaping structures may be required on fiber facets to…

Purpose: Endovascular aortic repair procedures are currently conducted with 2D fluoroscopy imaging. Tracking systems based on fiber Bragg gratings are an emerging technology for the navigation of minimal-invasive instruments which can…

Medical Physics · Physics 2019-09-10 Sonja Jäckle , Tim Eixmann , Hinnerk Schulz-Hildebrandt , Gereon Hüttmann , Torben Pätz

Optical fibres have transformed the way people interact with the world and now permeate many areas of science. Optical fibres are traditionally thought of as insensitive to magnetic fields, however many application areas from mining to…

Fiber dosimeters have recently drawn much interest for measuring in vivo and in real time the dose of medical radiations. This paper presents the first miniaturized fiber dosimeter integrated at the end of a narrow 125-micron outer diameter…

Interoperative measurements using magnetic sensors is a valuable technique in cancer surgery for finding magnetic tracers. Here we present a fiber-coupled nitrogen-vacancy (N-V) center magnetometer capable of detecting iron oxide suspension…

Medical Physics · Physics 2025-08-20 A. J. Newman , S. M. Graham , C. J. Stephen , A. M. Edmonds , M. L. Markham , G. W. Morley

Real-time measurement of relative humidity (RH) is important to many physical, chemical, and biological processes. However, in processes that involve harsh conditions such as high temperatures, strong electromagnetic interferences, and…

Instrumentation and Detectors · Physics 2023-07-12 Yundong Ren , Mucheng Li , Yuxiang Liu

Efficiently excite nitrogen-vacancy (NV) centers in diamond and collect their fluorescence significantly benefit the fiber-optic-based NV sensors. Here, using a tapered optical fiber (TOF) tip, we significantly improve the efficiency of the…

Nanodiamonds containing nitrogen-vacancy (NV) centers are promising quantum sensors for biological applications thanks to their sub-micron spatial resolution, biocompatibility, and versatile multi-modal responses. However, the optically…

Applied Physics · Physics 2026-03-23 Shuo Wang , Ming-Zhong Ai , Jing-Wei Fan , Junchen Ye , Chao Lin , Quan Li , Ren-Bao Liu

In this work, we study a new hollow-core (air-filled) double-clad anti-resonant fiber (DC-ARF) as a potent candidate for multiphoton micro-endoscopy. We compare the fiber characteristics with a single-clad anti-resonant fiber (SC-ARF) and a…

For several centuries, far-field optical microscopy has remained a key instrument in many scientific disciplines including physical, chemical and biomedical research. Nonetheless, far-field imaging has many limitations: the spatial…

Optics · Physics 2020-01-27 Lyubov V. Amitonova , Johannes F. de Boer

Multimode fibres are becoming increasingly attractive in optical endoscopy as they promise to enable unparalleled miniaturisation, spatial resolution and cost as compared to conventional fibre bundle-based counterpart. However, achieving…

Medical Physics · Physics 2024-06-05 Tianrui Zhao , Michelle T. Ma , Sebastien Ourselin , Tom Vercauteren , Wenfeng Xia

The lensless endoscope represents the ultimate limit in miniaturization of imaging tools: an image can be transmitted through a (multi-mode or multi-core) fiber by numerical or physical inversion of the fiber's pre-measured transmission…

We applied a tabletop, ultrafast, high-harmonic generation (HHG) source to measure the element-specific ferromagnetic resonance (FMR) in ultra-thin magnetic alloys and multilayers on an opaque Si substrate. We demonstrate a continuous wave…

Materials Science · Physics 2024-04-25 Michael Tanksalvala , Anthony Kos , Jacob Wisser , Scott Diddams , Hans T. Nembach , Justin M. Shaw

Optical nanofibers (ONF) of subwavelength dimensions confine light in modes with a strong evanescent field that can trap, probe, and manipulate nearby quantum systems. To measure the evanescent field and propagating modes, and to optimize…

We report quantitative measurements of optically detected ferromagnetic resonance (ODFMR) of ferromagnetic thin films that use nitrogen-vacancy (NV) centers in diamonds to transduce FMR into a fluorescence intensity variation. To uncover…