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Similarity metrics, e.g., signatures as used by anti-virus products, are the dominant technique to detect if a given binary is malware. The underlying assumption of this approach is that all instances of a malware (or even malware family)…

Cryptography and Security · Computer Science 2014-09-30 Mathias Payer , Stephen Crane , Per Larsen , Stefan Brunthaler , Richard Wartell , Michael Franz

Detecting predictive biomarkers from multi-omics data is important for precision medicine, to improve diagnostics of complex diseases and for better treatments. This needs substantial experimental efforts that are made difficult by the…

Quantitative Methods · Quantitative Biology 2021-06-08 Betül Güvenç Paltun , Samuel Kaski , Hiroshi Mamitsuka

We introduce Lumina-DiMOO, an open-source foundational model for seamless multi-modal generation and understanding. Lumina-DiMOO sets itself apart from prior unified models by utilizing a fully discrete diffusion modeling to handle inputs…

Despite the widespread use of deep learning methods for semantic segmentation of images that are acquired from a single source, clinicians often use multi-domain data for a detailed analysis. For instance, CT and MRI have advantages over…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Bora Baydar , Savas Ozkan , A. Emre Kavur , N. Sinem Gezer , M. Alper Selver , Gozde Bozdagi Akar

Linearized string representations serve as the foundation of scalable autoregressive molecular generation; however, they introduce a fundamental modality mismatch where a single molecular graph maps to multiple distinct sequences. This…

Machine Learning · Computer Science 2026-03-27 Xinyu Wang , Fei Dou , Jinbo Bi , Minghu Song

We investigate an application in the automatic tuning of computer codes, an area of research that has come to prominence alongside the recent rise of distributed scientific processing and heterogeneity in high-performance computing…

Applications · Statistics 2013-04-17 Robert B. Gramacy , Matt Taddy , Stefan M. Wild

We introduce Diddy, a collection of Python scripts for analyzing infinite discrete dynamical systems. The main focus is on generalized multidimensional shifts of finite type (SFTs). We show how Diddy can be used to easily define SFTs and…

Mathematical Software · Computer Science 2023-05-03 Ville Salo , Ilkka Törmä

Computer programs written in one language are often required to be ported to other languages to support multiple devices and environments. When programs use language specific APIs (Application Programming Interfaces), it is very challenging…

Software Engineering · Computer Science 2017-04-26 Xiaodong Gu , Hongyu Zhang , Dongmei Zhang , Sunghun Kim

Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the cellular level. By providing data on gene expression for each individual cell, scRNA-seq generates large datasets with thousands of…

Computational Complexity · Computer Science 2025-02-11 Md Romizul Islam , Swakkhar Shatabda

Model inversion attacks (MIAs) aim to reconstruct private images from a target classifier's training set, thereby raising privacy concerns in AI applications. Previous GAN-based MIAs tend to suffer from inferior generative fidelity due to…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Ouxiang Li , Yanbin Hao , Zhicai Wang , Bin Zhu , Shuo Wang , Zaixi Zhang , Fuli Feng

Mixed-integer linear programming (MILP) stands as a notable NP-hard problem pivotal to numerous crucial industrial applications. The development of effective algorithms, the tuning of solvers, and the training of machine learning models for…

Machine Learning · Computer Science 2023-10-23 Haoyu Wang , Jialin Liu , Xiaohan Chen , Xinshang Wang , Pan Li , Wotao Yin

Medical document analysis plays a crucial role in extracting essential clinical insights from unstructured healthcare records, supporting critical tasks such as differential diagnosis. Determining the most probable condition among…

Artificial Intelligence · Computer Science 2025-06-25 Lei Kang , Xuanshuo Fu , Oriol Ramos Terrades , Javier Vazquez-Corral , Ernest Valveny , Dimosthenis Karatzas

We present Piva (Preserving Identity with Variational Score Distillation), a novel optimization-based method for editing images and 3D models based on diffusion models. Specifically, our approach is inspired by the recently proposed method…

Computer Vision and Pattern Recognition · Computer Science 2024-06-14 Duong H. Le , Tuan Pham , Aniruddha Kembhavi , Stephan Mandt , Wei-Chiu Ma , Jiasen Lu

Intermittently powered devices rely on opportunistic energy-harvesting to function, leading to recurrent power interruptions. This paper introduces DiCA, a proposal for a hardware/software co-design to create differential check-points in…

Hardware Architecture · Computer Science 2023-08-28 Antonio Joia Neto , Adam Caulfield , Chistabelle Alvares , Ivan De Oliveira Nunes

This paper is focused on code-domain non-orthogonal multiple access (CD-NOMA), which is an emerging paradigm to support massive connectivity for future machine-type wireless networks. We take a comparative approach to study two types of…

Information Theory · Computer Science 2020-09-10 Zilong Liu , Lie-Liang Yang

Principal component analysis (PCA) has well-documented merits for data extraction and dimensionality reduction. PCA deals with a single dataset at a time, and it is challenged when it comes to analyzing multiple datasets. Yet in certain…

Machine Learning · Computer Science 2017-10-27 Gang Wang , Jia Chen , Georgios B. Giannakis

Multiple instance learning (MIL) has emerged as the dominant paradigm for whole slide image (WSI) analysis in computational pathology, achieving strong diagnostic performance through patch-level feature aggregation. However, existing MIL…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Yiran Song , Yikai Zhang , Shuang Zhou , Guojun Xiong , Xiaofeng Yang , Nian Wang , Fenglong Ma , Rui Zhang , Mingquan Lin

This paper introduces a novel framework for DNA sequence generation, comprising two key components: DiscDiff, a Latent Diffusion Model (LDM) tailored for generating discrete DNA sequences, and Absorb-Escape, a post-training algorithm…

Genomics · Quantitative Biology 2024-04-18 Zehui Li , Yuhao Ni , William A V Beardall , Guoxuan Xia , Akashaditya Das , Guy-Bart Stan , Yiren Zhao

Multivariate Analysis (MVA) comprises a family of well-known methods for feature extraction which exploit correlations among input variables representing the data. One important property that is enjoyed by most such methods is uncorrelation…

Machine Learning · Computer Science 2021-12-24 Sergio Muñoz-Romero , Vanessa Gómez-Verdejo , Jerónimo Arenas-García

Background: Advances in high throughput sequencing technologies provide a huge number of genomes to be analyzed. Thus, computational methods play a crucial role in analyzing and extracting knowledge from the data generated. Investigating…