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Many analyses of functional magnetic resonance imaging (fMRI) examine functional connectivity (FC), or the statistical dependencies among distant brain regions. These analyses are typically exploratory, guiding future confirmatory research.…

Applications · Statistics 2025-10-20 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Many fMRI analyses examine functional connectivity, or statistical dependencies among remote brain regions. Yet popular methods for studying whole-brain functional connectivity often yield results that are difficult to interpret. Factor…

Methodology · Statistics 2024-09-24 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Functional MRI data exhibit high-dimensional spatiotemporal structure, making both prediction and decoding challenging. In this work, we investigate neural integral-operator-based models for encoding and decoding tasks in fMRI, with…

Machine Learning · Computer Science 2026-05-21 Andreas Kramer , Saugat Acharya , Alice Giola , Emanuele Zappala

Multivariate spatio-temporal data arise more and more frequently in a wide range of applications; however, there are relatively few general statistical methods that can readily use that incorporate spatial, temporal and variable…

Methodology · Statistics 2017-11-15 Elynn Yi Chen , Qiwei Yao , Rong Chen

Multi-subject fMRI studies are challenging due to the high variability of both brain anatomy and functional brain topographies across participants. An effective way of aggregating multi-subject fMRI data is to extract a shared…

Neurons and Cognition · Quantitative Biology 2020-09-08 MohammadReza Ebrahimi , Navona Calarco , Kieran Campbell , Colin Hawco , Aristotle Voineskos , Ashish Khisti

This article introduces novel and practicable Bayesian factor analysis frameworks that are computationally feasible for moderate to large spatiotemporal data. Previous Bayesian analysis of spatiotemporal data has utilized a Bayesian factor…

Methodology · Statistics 2025-02-18 Yifan Cheng , Cheng Li

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

Functional magnetic resonance imaging (fMRI) is a neuroimaging technique known for its ability to capture brain activity non-invasively and at fine spatial resolution (2-3mm). Cortical surface fMRI (cs-fMRI) is a recent development of fMRI…

Applications · Statistics 2023-12-29 Huy Dang , Marzia Cremona , Nicole Lazar , Francesca Chiaromonte

Functional Magnetic Resonance Imaging (fMRI) is a primary modality for studying brain activity. Modeling spatial dependence of imaging data at different scales is one of the main challenges of contemporary neuroimaging, and it could allow…

Applications · Statistics 2016-06-16 Stefano Castruccio , Hernando Ombao , Marc G. Genton

Segmentation of Multiple Sclerosis (MS) lesions in longitudinal brain MR scans is performed for monitoring the progression of MS lesions. We hypothesize that the spatio-temporal cues in longitudinal data can aid the segmentation algorithm.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-29 Stefan Denner , Ashkan Khakzar , Moiz Sajid , Mahdi Saleh , Ziga Spiclin , Seong Tae Kim , Nassir Navab

Functional Magnetic Resonance Images acquired during resting-state provide information about the functional organization of the brain through measuring correlations between brain areas. Independent components analysis is the reference…

Neurons and Cognition · Quantitative Biology 2014-12-15 Alexandre Abraham , Elvis Dohmatob , Bertrand Thirion , Dimitris Samaras , Gael Varoquaux

There is a growing interest in joint multi-subject fMRI analysis. The challenge of such analysis comes from inherent anatomical and functional variability across subjects. One approach to resolving this is a shared response factor model.…

High-dimensional multivariate spatial-temporal data arise frequently in a wide range of applications; however, there are relatively few statistical methods that can simultaneously deal with spatial, temporal and variable-wise dependencies…

Methodology · Statistics 2020-02-05 Elynn Y. Chen , Xin Yun , Rong Chen , Qiwei Yao

In this work, we present an additive model for space-time data that splits the data into a temporally correlated component and a spatially correlated component. We model the spatially correlated portion using a time-varying Gaussian…

Methodology · Statistics 2017-11-13 Kristjan Greenewald , Seyoung Park , Shuheng Zhou , Alexander Giessing

Finding the most effective way to aggregate multi-subject fMRI data is a long-standing and challenging problem. It is of increasing interest in contemporary fMRI studies of human cognition due to the scarcity of data per subject and the…

The partially separable functions (PSF) model is commonly adopted in dynamic MRI reconstruction, as is the underlying signal model in many reconstruction methods including the ones relying on low-rank assumptions. Even though the PSF model…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Rodrigo A. Lobos , Xiaokai Wang , Rex T. L. Fung , Yongli He , David Frey , Dinank Gupta , Zhongming Liu , Jeffrey A. Fessler , Douglas C. Noll

Modelling multivariate spatio-temporal data with complex dependency structures is a challenging task but can be simplified by assuming that the original variables are generated from independent latent components. If these components are…

Methodology · Statistics 2024-11-04 Mika Sipilä , Claudia Cappello , Sandra De Iaco , Klaus Nordhausen , Sara Taskinen

The success and generalisation of deep learning algorithms heavily depend on learning good feature representations. In medical imaging this entails representing anatomical information, as well as properties related to the specific imaging…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Agisilaos Chartsias , Thomas Joyce , Giorgos Papanastasiou , Scott Semple , Michelle Williams , David Newby , Rohan Dharmakumar , Sotirios A. Tsaftaris

Spatiotemporal dynamics is central to a wide range of applications from climatology, computer vision to neural sciences. From temporal observations taken on a high-dimensional vector of spatial locations, we seek to derive knowledge about…

Methodology · Statistics 2016-04-19 Lu Meng , Tian Zheng

A major tenet in theoretical neuroscience is that cognitive and behavioral processes are ultimately implemented in terms of the neural system dynamics. Accordingly, a major aim for the analysis of neurophysiological measurements should lie…

Machine Learning · Computer Science 2020-07-01 Georgia Koppe , Hazem Toutounji , Peter Kirsch , Stefanie Lis , Daniel Durstewitz
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