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Model predictive control (MPC) is a powerful tool for controlling complex nonlinear systems under constraints, but often struggles with model uncertainties and the design of suitable cost functions. To address these challenges, we discuss…

Systems and Control · Electrical Eng. & Systems 2024-10-08 Sebastian Hirt , Andreas Höhl , Johannes Pohlodek , Joachim Schaeffer , Maik Pfefferkorn , Richard D. Braatz , Rolf Findeisen

Disorders of consciousness are a heterogeneous mixture of different diseases or injuries. Although some indicators and models have been proposed for prognostication, any single method when used alone carries a high risk of false prediction.…

Neurons and Cognition · Quantitative Biology 2018-09-10 Ming Song , Yi Yang , Jianghong He , Zhengyi Yang , Shan Yu , Qiuyou Xie , Xiaoyu Xia , Yuanyuan Dang , Qiang Zhang , Xinhuai Wu , Yue Cui , Bing Hou , Ronghao Yu , Ruxiang Xu , Tianzi Jiang

Multiple Sclerosis is a degenerative condition of the central nervous system that affects nearly 2.5 million of individuals in terms of their physical, cognitive, psychological and social capabilities. Researchers are currently…

Machine Learning · Statistics 2016-12-05 Samuele Fiorini , Andrea Tacchino , Giampaolo Brichetto , Alessandro Verri , Annalisa Barla

Background: A therapeutic intervention in psychiatry can be viewed as an attempt to influence the brain's large-scale, dynamic network state transitions underlying cognition and behavior. Building on connectome-based graph analysis and…

This work introduces a formulation of model predictive control (MPC) which adaptively reasons about the complexity of the model based on the task while maintaining feasibility and stability guarantees. Existing MPC implementations often…

Robotics · Computer Science 2024-11-07 Joseph Norby , Ardalan Tajbakhsh , Yanhao Yang , Aaron M. Johnson

The integration of mobile health (mHealth) devices into behavioral health research has fundamentally changed the way researchers and interventionalists are able to collect data as well as deploy and evaluate intervention strategies. In…

Methodology · Statistics 2021-12-17 Matthew D. Koslovsky , Emily T. Hebert , Michael S. Businelle , Marina Vannucci

Prominent features of simulated moving bed (SMB) chromatography processes in the downstream processing is based on the determination of operating conditions. However, effects of different types of uncertainties have to be studied and…

Computational Engineering, Finance, and Science · Computer Science 2021-07-16 Qiao-Le He , Liming Zhao

This work investigates the challenge of ensuring safety guarantees in the presence of uncontrollable agents, whose behaviors are stochastic and depend on both their own and the system's states. We present a neural model predictive control…

Systems and Control · Electrical Eng. & Systems 2026-04-21 Shuqi Wang , Mingyang Feng , Yu Chen , Yue Gao , Xiang Yin

Background: Cannabis use disorder (CUD) is a growing public health problem. Early identification of adolescents and young adults at risk of developing CUD in the future may help stem this trend. A logistic regression model fitted using a…

Model predictive control (MPC) is an optimal control method that predicts the future states of the system being controlled and estimates the optimal control inputs that drive the predicted states to the required reference. The computations…

Systems and Control · Electrical Eng. & Systems 2023-05-05 Eslam Mostafa , Hussein A. Aly , Ahmed Elliethy

This paper studies an optimal control problem for an adoption-opinion model that couples innovation adoption with opinion formation on a multilayer network. Adoption spreads through social contagion and perceived benefits, while opinions…

Optimization and Control · Mathematics 2025-11-13 Martina Alutto , Qiulin Xu , Fabrizio Dabbene , Hideaki Ishii , Chiara Ravazzi

We present a chance-constrained model predictive control (MPC) framework under Gaussian mixture model (GMM) uncertainty. Specifically, we consider the uncertainty that arises from predicting future behaviors of moving obstacles, which may…

Systems and Control · Electrical Eng. & Systems 2025-07-21 Kai Ren , Colin Chen , Hyeontae Sung , Heejin Ahn , Ian Mitchell , Maryam Kamgarpour

To extend healthy life expectancy in an aging society, it is crucial to prevent various diseases at pre-disease states. Although dynamical network biomarker theory has been developed for pre-disease detection, mathematical frameworks for…

Optimization and Control · Mathematics 2026-01-07 Makito Oku

Model Predictive Control (MPC) is a widely used technique for managing timevarying systems, supported by extensive theoretical analysis. While theoretical studies employing dynamic regret frameworks have established robust performance…

Systems and Control · Electrical Eng. & Systems 2025-02-20 Nhat M. Nguyen

Model Predictive Control (MPC) is a powerful framework for constrained control, but its performance and safety can be severely degraded when the prediction model is learned online and thus remains uncertain. In this work, we develop a…

Optimization and Control · Mathematics 2025-12-01 Yingke Li , Yifan Lin , Enlu Zhou , Fumin Zhang

Model predictive control (MPC) provides a useful means for controlling systems with constraints, but suffers from the computational burden of repeatedly solving an optimization problem in real time. Offline (explicit) solutions for MPC…

Systems and Control · Electrical Eng. & Systems 2022-09-14 Daniel Tabas , Baosen Zhang

Observational studies are regarded as economic alternatives to randomized trials, often used in their stead to investigate and determine treatment efficacy. Due to lack of sample size, observational studies commonly combine data from…

Machine Learning · Statistics 2022-05-16 Tianhui Zhou , William E. Carson , Michael Hunter Klein , David Carlson

This study introduces an integrated framework for predictive causal inference designed to overcome limitations inherent in conventional single model approaches. Specifically, we combine a Hidden Markov Model (HMM) for spatial health state…

Methodology · Statistics 2025-10-31 Byunghee Lee , Hye Yeon Sin , Joonsung Kang

In this paper, we propose a model predictive control (MPC) method for real-time intervention of spreading processes, such as epidemics and wildfire, over large-scale networks. The goal is to allocate budgeted resources each time step to…

Optimization and Control · Mathematics 2022-10-31 Ruigang Wang , Armaghan Zafar , Ian R. Manchester

This paper proposes an iterative distributionally robust model predictive control (MPC) scheme to solve a risk-constrained infinite-horizon optimal control problem. In each iteration, the algorithm generates a trajectory from the starting…

Optimization and Control · Mathematics 2023-08-23 Alireza Zolanvari , Ashish Cherukuri