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Survival analysis is a technique to predict the times of specific outcomes, and is widely used in predicting the outcomes for intensive care unit (ICU) trauma patients. Recently, deep learning models have drawn increasing attention in…

Artificial Intelligence · Computer Science 2021-03-22 Yun Zhao , Qinghang Hong , Xinlu Zhang , Yu Deng , Yuqing Wang , Linda Petzold

Accurate survival prediction in Non-Small Cell Lung Cancer (NSCLC) requires integrating clinical, radiological, and histopathological data. Multimodal Deep Learning (MDL) can improve precision prognosis, but small cohorts and missing…

Fusing multi-modal data can improve the performance of deep learning models. However, missing modalities are common for medical data due to patients' specificity, which is detrimental to the performance of multi-modal models in…

Image and Video Processing · Electrical Eng. & Systems 2023-09-28 Muyu Wang , Shiyu Fan , Yichen Li , Hui Chen

The control of neuronal networks, whether biological or neuromorphic, relies on tools for estimating parameters in the presence of model uncertainty. In this work, we explore the robustness of adaptive observers for neuronal estimation.…

Systems and Control · Electrical Eng. & Systems 2023-09-11 Raphael Schmetterling , Thiago B. Burghi , Rodolphe Sepulchre

As medical diagnoses increasingly leverage multimodal data, machine learning models are expected to effectively fuse heterogeneous information while remaining robust to missing modalities. In this work, we propose a novel multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yi Gu , Kuniaki Saito , Jiaxin Ma

While most existing epidemic models focus on the influence of isolated factors, infectious disease transmission is inherently shaped by the complex interplay of multiple interacting elements. To better capture real-world dynamics, it is…

Physics and Society · Physics 2025-04-18 Guangyuan Mei , Yao Cai , Su-Su Zhang , Ying Huang , Chuang Liu , Xiu-Xiu Zhan

Complex systems such as aircraft engines, turbines, and industrial machinery often operate under dynamically changing conditions. These varying operating conditions can substantially influence degradation behavior and make prognostic…

Machine Learning · Computer Science 2026-04-14 Yuqi Su , Xiaolei Fang

Multimodal clinical data are characterized by high dimensionality, heterogeneous representations, and structured missingness, posing significant challenges for predictive modeling, data integration, and interpretability. We propose BIONIC…

Early prediction of patients at risk of clinical deterioration can help physicians intervene and alter their clinical course towards better outcomes. In addition to the accuracy requirement, early warning systems must make the predictions…

Machine Learning · Computer Science 2021-02-16 Ibrahim Hammoud , Prateek Prasanna , IV Ramakrishnan , Adam Singer , Mark Henry , Henry Thode

The problem of missing data, usually absent incurated and competition-standard datasets, is an unfortunate reality for most machine learning models used in industry applications. Recent work has focused on understanding the nature and the…

Machine Learning · Computer Science 2022-01-25 Spyridon Mouselinos , Kyriakos Polymenakos , Antonis Nikitakis , Konstantinos Kyriakopoulos

The aging world population requires a sustainable and high-quality healthcare system. To examine the efficiency of medical cooperation, medical provider and physician networks were constructed using patient claims data. Previous studies…

Physics and Society · Physics 2022-08-30 Yu Ohki , Yuichi Ikeda , Susumu Kunisawa , Yuichi Imanaka

We consider the optimization of an uncertain objective over continuous and multi-dimensional decision spaces in problems in which we are only provided with observational data. We propose a novel algorithmic framework that is tractable,…

Machine Learning · Statistics 2018-10-30 Dimitris Bertsimas , Christopher McCord

Longitudinal clinical notes contain rich evidence of how patients evolve over time, but converting this signal into training supervision for clinical prediction remains challenging. We extend Foresight Learning to clinical prediction by…

Machine Learning · Computer Science 2026-05-14 Benjamin Turtel , Paul Wilczewski , Kris Skotheim

The problem of dynamic prediction with time-dependent covariates, given by biomarkers, repeatedly measured over time, has received much attention over the last decades. Two contrasting approaches have become in widespread use. The first is…

Methodology · Statistics 2021-03-31 Hein Putter , Hans C. van Houwelingen

Survival analysis is an essential tool for the study of health data. An inherent component of such data is the presence of missing values. In recent years, researchers proposed new learning algorithms for survival tasks based on neural…

Machine Learning · Statistics 2023-03-27 Paul Dufossé , Sébastien Benzekry

Motivation: Identification of genomic, molecular and clinical markers prognostic of patient survival is important for developing personalized disease prevention, diagnostic and treatment approaches. Modern omics technologies have made it…

Applications · Statistics 2024-03-05 Zhi Zhao , John Zobolas , Manuela Zucknick , Tero Aittokallio

Data collected in clinical trials are often composed of multiple types of variables. For example, laboratory measurements and vital signs are longitudinal data of continuous or categorical variables, adverse events may be recurrent events,…

Methodology · Statistics 2023-01-12 Tuo Wang , Rachel Zilinskas , Ying Li , Yongming Qu

Repeated measures of biomarkers have the potential of explaining hazards of survival outcomes. In practice, these measurements are intermittently measured and are known to be subject to substantial measurement error. Joint modelling of…

Applications · Statistics 2019-12-12 Lisa McFetridge , Ozgur Asar , Jonas Wallin

Recent advances in clinical AI have enabled remarkable progress across many clinical domains. However, existing benchmarks and models are primarily limited to a small set of modalities and tasks, which hinders the development of large-scale…

Machine Learning · Computer Science 2025-03-21 Wei Dai , Peilin Chen , Malinda Lu , Daniel Li , Haowen Wei , Hejie Cui , Paul Pu Liang

Large Language Models (LLMs) are increasingly being explored for clinical question answering and decision support, yet safe deployment critically requires reliable handling of patient measurements in heterogeneous clinical notes. Existing…

Computation and Language · Computer Science 2026-04-16 Minh-Vuong Nguyen , Fatemeh Shiri , Zhuang Li , Karin Verspoor