English
Related papers

Related papers: Unpredictable repeatability in molecular evolution

200 papers

The directed preferential attachment model is revisited. A new exact characterization of the limiting in- and out-degree distribution is given by two \emph{independent} pure birth processes that are observed at a common exponentially…

Probability · Mathematics 2018-10-08 Tom Britton

Many researchers have identified distribution shift as a likely contributor to the reproducibility crisis in behavioral and biomedical sciences. The idea is that if treatment effects vary across individual characteristics and experimental…

Applications · Statistics 2023-09-06 Ying Jin , Kevin Guo , Dominik Rothenhäusler

We study the adaptation dynamics of an initially maladapted asexual population with genotypes represented by binary sequences of length $L$. The population evolves in a maximally rugged fitness landscape with a large number of local optima.…

Populations and Evolution · Quantitative Biology 2007-05-23 Kavita Jain , Joachim Krug

The notion of expectiles, originally introduced in the context of testing for homoscedasticity and conditional symmetry of the error distribution in linear regression, induces a law-invariant, coherent and elicitable risk measure that has…

Methodology · Statistics 2020-07-20 Simone A. Padoan , Gilles Stupfler

We test whether artificial intelligence architectural evolution obeys the same statistical laws as biological evolution. Compiling 935 ablation experiments from 161 publications, we show that the distribution of fitness effects (DFE) of…

Populations and Evolution · Quantitative Biology 2026-04-14 Theodor Spiro

The tail of the distribution of a sum of a random number of independent and identically distributed nonnegative random variables depends on the tails of the number of terms and of the terms themselves. This situation is of interest in the…

Probability · Mathematics 2008-12-10 Christian Y. Robert , Johan Segers

Convergence of discrete-time Markov chains with two timescales is a powerful tool to study stochastic evolutionary games in subdivided populations. Focusing on linear games within demes, convergence to a diffusion process for the strategy…

Populations and Evolution · Quantitative Biology 2024-11-05 Sabin Lessard

Community assembly is studied using individual-based multispecies models. The models have stochastic population dynamics with mutation, migration, and extinction of species. Mutants appear as a result of mutation of the resident species,…

Populations and Evolution · Quantitative Biology 2010-05-18 Yohsuke Murase , Takashi Shimada , Nobuyasu Ito , Per Arne Rikvold

Heterogeneity in biological molecules, resulting in molecule-to-molecule variations in their dynamics and function, is an emerging theme. To elucidate the consequences of heterogeneous behavior at the single molecule level, we propose an…

Biological Physics · Physics 2017-01-24 Changbong Hyeon , Michael Hinczewski , D. Thirumalai

Conventional population genetics considers the evolution of a limited number of genotypes corresponding to phenotypes with different fitness. As model phenotypes, in particular RNA secondary structure, have become computationally tractable,…

Populations and Evolution · Quantitative Biology 2008-04-22 Gergely J. Szollosi , Imre Derenyi

Phenotypic fluctuations and plasticity can generally affect the course of evolution, a process known as the Baldwin effect. Several studies have recast this effect and claimed that phenotypic plasticity acceler- ates evolutionary rate (the…

Populations and Evolution · Quantitative Biology 2013-05-30 Nen Saito , Shuji Ishihara , Kunihiko Kaneko

Epidemic disease spreading is conventionally often modelled and analyzed by means of rate and diffusion equations, following the paradigms of well-controlled chemical reactions and diffusive dynamics in a test tube. Yet, serious worries…

Physics and Society · Physics 2023-01-03 Klaus Kroy

The evolution and function of imitation have always been placed within the confines of animal learning and associated with its crucial role in cultural transmission and cultural evolution. Can imitation evolve as a form of phenotypic…

Populations and Evolution · Quantitative Biology 2021-10-22 Lee Altenberg , Susanne Still , Christopher J. Watkins

We consider fully connected and feedforward deep neural networks with dependent and possibly heavy-tailed weights, as introduced in [26], to address limitations of the standard Gaussian prior. It has been proved in [26] that, as the number…

Machine Learning · Statistics 2026-05-14 Nicola Apollonio , Giovanni Franzina , Giovanni Luca Torrisi

It is well-known that the expected scaled maximum of non-negative random variables with unit mean defines a stable tail dependence function associated with some extreme-value copula. In the special case when these random variables are…

Methodology · Statistics 2018-05-30 Jan-Frederik Mai

We propose a Bayesian approach using improper priors for hierarchical linear mixed models with flexible random effects and residual error distributions. The error distribution is modelled using scale mixtures of normals, which can capture…

Methodology · Statistics 2018-02-06 F. J. Rubio , M. F. J. Steel

In large asexual populations, multiple beneficial mutations arise in the population, compete, interfere with each other, and accumulate on the same genome, before any of them fix. The resulting dynamics, although studied by many authors, is…

Populations and Evolution · Quantitative Biology 2015-06-11 Daniel S. Fisher

This paper investigates how often the popular configurations of Differential Evolution generate solutions outside the feasible domain. Following previous publications in the field, we argue that what the algorithm does with such solutions…

Neural and Evolutionary Computing · Computer Science 2022-01-19 Anna V. Kononova , Fabio Caraffini , Thomas Bäck

We study the large-time asymptotic of renewal-reward processes with a heavy-tailed waiting time distribution. It is known that the heavy tail of the distribution produces an extremely slow dynamics, resulting in a singular large deviation…

Mathematical Physics · Physics 2022-01-05 Hiroshi Horii , Raphael Lefevere , Takahiro Nemoto

Evolutionary graph theory (EGT) studies the effect of population structure on evolutionary dynamics. The vertices of the graph represent the $N$ individuals. The edges denote interactions for competitive replacement. Two standard update…

Populations and Evolution · Quantitative Biology 2026-04-01 David A. Brewster , Yichen Huang , Michael Mitzenmacher , Martin A. Nowak