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Natural dynamical systems, including the brain and climate, are highly nonlinear and complex. Determining information flow among the components that make up these dynamical systems is challenging. If the components are the result of a…
Heart diseases constitute a global health burden, and the problem is exacerbated by the error-prone nature of listening to and interpreting heart sounds. This motivates the development of automated classification to screen for abnormal…
Learning the unique directed acyclic graph corresponding to an unknown causal model is a challenging task. Methods based on functional causal models can identify a unique graph, but either suffer from the curse of dimensionality or impose…
Discovering causal relationships from time series data is significant in fields such as finance, climate science, and neuroscience. However, contemporary techniques rely on the simplifying assumption that data originates from the same…
Alterations in the geometry and function of the heart define well-established causes of cardiovascular disease. However, current approaches to the diagnosis of cardiovascular diseases often rely on subjective human assessment as well as…
The construction of computer models (mathematical models implemented in computer codes), with respect to observed phenomena, is usually undertaken by building different variants depending on modeller sensibility, and choosing the one…
Bayesian networks are powerful statistical models to study the probabilistic relationships among set random variables with major applications in disease modeling and prediction. Here, we propose a continuous time Bayesian network with…
Causal reasoning in natural language requires identifying relevant variables, understanding their interactions, and reasoning about effects and interventions, often under noisy or ambiguous conditions. While large language models (LLMs)…
Mathematical models are increasing adopted for setting targets for disease prevention and control. As model-informed policies are implemented, however, the inaccuracies of some forecasts become apparent, for example overprediction of…
We address the problem of two-variable causal inference without intervention. This task is to infer an existing causal relation between two random variables, i.e. $X \rightarrow Y$ or $Y \rightarrow X$ , from purely observational data. As…
With the evolution of single-cell RNA sequencing techniques into a standard approach in genomics, it has become possible to conduct cohort-level causal inferences based on single-cell-level measurements. However, the individual gene…
Medical image segmentation is crucial for clinical applications, but it is frequently disrupted by noisy annotations and ambiguous anatomical boundaries, limiting its application in real-world scenarios. Existing methods often directly…
We consider causal discovery in structural causal models driven by heavy-tailed noise, where extremes carry important information about causal direction. We introduce the Heavy-Tailed Homogeneous Structural Causal Model (HT-HSCM), a unified…
We consider the problem of learning the weighted edges of a graph by observing the noisy times of infection for multiple epidemic cascades on this graph. Past work has considered this problem when the cascade information, i.e., infection…
In many scientific disciplines, coarse-grained causal models are used to explain and predict the dynamics of more fine-grained systems. Naturally, such models require appropriate macrovariables. Automated procedures to detect suitable…
The objective function of a matrix factorization model usually aims to minimize the average of a regression error contributed by each element. However, given the existence of stochastic noises, the implicit deviations of sample data from…
Precise and efficient automated identification of Gastrointestinal (GI) tract diseases can help doctors treat more patients and improve the rate of disease detection and identification. Currently, automatic analysis of diseases in the GI…
The advent of molecular biology has led to the identification of definitive causative factors for a number of diseases, most of which are monogenic. Causes for most common diseases across the population, however, seem elusive and cannot be…
Automatic chest X-ray report generation is an important area of research aimed at improving diagnostic accuracy and helping doctors make faster decisions. Current AI models are good at finding correlations (or patterns) in medical images.…
Medical image segmentation plays a vital role in clinical decision-making, enabling precise localization of lesions and guiding interventions. Despite significant advances in segmentation accuracy, the black-box nature of most deep models…