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The complexity of mathematical models describing respiratory mechanics has grown in recent years to integrate with cardiovascular models and incorporate nonlinear dynamics. However, additional model complexity has rarely been studied in the…

Tissues and Organs · Quantitative Biology 2020-01-17 Laura Ellwein Fix

This paper studies adaptive first-order least-squares finite element methods for second-order elliptic partial differential equations in non-divergence form. Unlike the classical finite element method which uses weak formulations of PDEs…

Numerical Analysis · Mathematics 2019-06-28 Weifeng Qiu , Shun Zhang

Cardiovascular disease accounts for 1 in every 4 deaths in United States. Accurate estimation of structural and functional cardiac parameters is crucial for both diagnosis and disease management. In this work, we develop an ensemble…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Jiasha Liu , Xiang Li , Hui Ren , Quanzheng Li

Myocardial Velocity Mapping Cardiac MR (MVM-CMR) can be used to measure global and regional myocardial velocities with proved reproducibility. Accurate left ventricle delineation is a prerequisite for robust and reproducible myocardial…

Image and Video Processing · Electrical Eng. & Systems 2021-04-28 Mengmeng Kuang , Yinzhe Wu , Diego Alonso-Álvarez , David Firmin , Jennifer Keegan , Peter Gatehouse , Guang Yang

Heart disorder has just overtaken cancer as the world's biggest cause of mortality. Several cardiac failures, heart disease mortality, and diagnostic costs can all be reduced with early identification and treatment. Medical data is…

Machine Learning · Computer Science 2023-04-13 Md. Maidul Islam , Tanzina Nasrin Tania , Sharmin Akter , Kazi Hassan Shakib

Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no…

Computational Engineering, Finance, and Science · Computer Science 2021-06-28 Martin R. Pfaller , Jonathan Pham , Nathan M. Wilson , David W. Parker , Alison L. Marsden

In the United States, heart disease is the leading cause of death for both men and women, accounting for 610,000 deaths each year [1]. Physicians use Magnetic Resonance Imaging (MRI) scans to take images of the heart in order to…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Ehab Abdelmaguid , Jolene Huang , Sanjay Kenchareddy , Disha Singla , Laura Wilke , Mai H. Nguyen , Ilkay Altintas

We introduce an innovative lumped-parameter model of the aortic valve, designed to efficiently simulate the impact of valve dynamics on blood flow. Our reduced model includes the elastic effects associated with the leaflets' curvature and…

Numerical Analysis · Mathematics 2025-04-15 Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

The present focus of heart flow studies is largely based on flow within the left ventricle and how this flow changes when subject to disease. However, despite recent advancements, a simple tractable model of even healthy left ventricular…

Fluid Dynamics · Physics 2019-03-18 Giuseppe Di Labbio , Lyes Kadem

Estimation of cardiovascular model parameters from electronic health records (EHR) poses a significant challenge primarily due to lack of identifiability. Structural non-identifiability arises when a manifold in the space of parameters is…

Numerical Analysis · Mathematics 2024-08-16 Guoxiang Grayson Tong , Carlos A. Sing Long , Daniele E. Schiavazzi

Optimization techniques play a crucial role in estimating parameters and state information for nonlinear systems. However, some critical aspects of these problems have received little attention in previous research. In this paper, we…

Optimization and Control · Mathematics 2023-06-02 Kaushal Kumar

Left ventricular (LV) indicator measurements following clinical echocardiog-raphy guidelines are important for diagnosing cardiovascular disease. Alt-hough existing algorithms have explored automated LV quantification, they can struggle to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Tuo Liu , Qinghan Yang , Yu Zhang , Rongjun Ge , Yang Chen , Guangquan Zhou

Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…

Numerical Analysis · Mathematics 2024-11-28 Kabir Bakhshaei , Sajad Salavatidezfouli , Giovanni Stabile , Gianluigi Rozza

Segmentation of the left ventricle and quantification of various cardiac contractile functions is crucial for the timely diagnosis and treatment of cardiovascular diseases. Traditionally, the two tasks have been tackled independently. Here…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Shusil Dangi , Ziv Yaniv , Cristian A. Linte

Based on CT and MRI images acquired from normal pressure hydrocephalus (NPH) patients, using machine learning methods, we aim to establish a multi-modal and high-performance automatic ventricle segmentation method to achieve efficient and…

Medical Physics · Physics 2022-02-02 Xi Zhou , Qinghao Ye , Xiaolin Yang , Jiakuan Chen , Haiqin Ma , Jun Xia , Javier Del Ser , Guang Yang

Manual segmentation of the Left Ventricle (LV) is a tedious and meticulous task that can vary depending on the patient, the Magnetic Resonance Images (MRI) cuts and the experts. Still today, we consider manual delineation done by experts as…

Computer Vision and Pattern Recognition · Computer Science 2018-01-09 Alexandre Attia , Sharone Dayan

Deep neural networks have shown great achievements in solving complex problems. However, there are fundamental problems that limit their real world applications. Lack of measurable criteria for estimating uncertainty in the network outputs…

Computer Vision and Pattern Recognition · Computer Science 2018-03-02 Alireza Norouzi , Ali Emami , S. M. Reza Soroushmehr , Nader Karimi , Shadrokh Samavi , Kayvan Najarian

Deep learning models in medical contexts face challenges like data scarcity, inhomogeneity, and privacy concerns. This study focuses on improving ventricular segmentation in brain MRI images using synthetic data. We employed two latent…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Tim Ruschke , Jonathan Frederik Carlsen , Adam Espe Hansen , Ulrich Lindberg , Amalie Monberg Hindsholm , Martin Norgaard , Claes Nøhr Ladefoged

Confidence in the results is a key ingredient to improve the adoption of machine learning methods by clinicians. Uncertainties on the results have been considered in the literature, but mostly those originating from the learning and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Maxime Di Folco , Gabriel Bernardino , Patrick Clarysse , Nicolas Duchateau

The clinical application of patient-specific modelling of the heart can provide valuable insights in supplementing and advancing methods of diagnosis as well as helping to devise the best possible therapeutic approach for each individual…

Medical Physics · Physics 2023-08-03 Sebastian Skatulla , Carlo Sansour , Mary Familusi , Jagir Hussan , Ntobeko Ntusi