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Coronary artery disease (CAD) is often treated minimally invasively with a catheter being inserted into the diseased coronary vessel. If a patient exhibits a Shepherd's Crook (SC) Right Coronary Artery (RCA) - an anatomical norm variant of…

Designing categorical kernels is a major challenge for Gaussian process regression with continuous and categorical inputs. Despite previous studies, it is difficult to identify a preferred method, either because the evaluation metrics, the…

Machine Learning · Statistics 2025-10-03 Raphaël Carpintero Perez , Sébastien Da Veiga , Josselin Garnier

Cardiac magnetic resonance imaging (CMR) offers detailed evaluation of cardiac structure and function, but its limited accessibility restricts use to selected patient populations. In contrast, the electrocardiogram (ECG) is ubiquitous and…

We develop a coarse grained (CG) approach for efficiently simulating calcium dynamics in the endoplasmic reticulum membrane based on a fine stochastic lattice gas model. By grouping neighboring microscopic sites together into CG cells and…

Chemical Physics · Physics 2015-06-15 Chuansheng Shen , Hanshuang Chen

As a means to extract biomarkers from medical imaging, radiomics has attracted increased attention from researchers. However, reproducibility and performance of radiomics in low dose CT scans are still poor, mostly due to noise. Deep…

Quantitative Methods · Quantitative Biology 2021-09-17 Junhua Chen , Leonard Wee , Andre Dekker , Inigo Bermejo

Variation in nuclear size and shape is an important criterion of malignancy for many tumor types; however, categorical estimates by pathologists have poor reproducibility. Measurements of nuclear characteristics (morphometry) can improve…

Computed tomography (CT) plays an important role in lung malignancy diagnostics and therapy assessment and facilitating precision medicine delivery. However, the use of personalized imaging protocols poses a challenge in large-scale…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Md Selim , Jie Zhang , Baowei Fei , Guo-Qiang Zhang , Jin Chen

Anatomical structures such as blood vessels in contrast-enhanced CT (ceCT) images can be challenging to segment due to the variability in contrast medium diffusion. The combined use of ceCT and contrast-free (CT) CT images can improve the…

Image and Video Processing · Electrical Eng. & Systems 2022-10-05 Giammarco La Barbera , Haithem Boussaid , Francesco Maso , Sabine Sarnacki , Laurence Rouet , Pietro Gori , Isabelle Bloch

Score-based generative models (SGMs) have gained prominence in sparse-view CT reconstruction for their precise sampling of complex distributions. In SGM-based reconstruction, data consistency in the score-based diffusion model ensures close…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Weiwen Wu , Yanyang Wang

Electrocardiogram (ECG) acquisition requires an automated system and analysis pipeline for understanding specific rhythm irregularities. Deep neural networks have become a popular technique for tracing ECG signals, outperforming human…

Background and Objective: Only about 14 % of eligible EU citizens finally participate in colorectal cancer (CRC) screening programs despite it being the third most common type of cancer worldwide. The development of CRC risk models can…

Cardiac magnetic resonance imaging improves on diagnosis of cardiovascular diseases by providing images at high spatiotemporal resolution. Manual evaluation of these time-series, however, is expensive and prone to biased and…

Computer Vision and Pattern Recognition · Computer Science 2018-04-06 Fabian Isensee , Paul Jaeger , Peter M. Full , Ivo Wolf , Sandy Engelhardt , Klaus H. Maier-Hein

Alterations in the geometry and function of the heart define well-established causes of cardiovascular disease. However, current approaches to the diagnosis of cardiovascular diseases often rely on subjective human assessment as well as…

Computer Vision and Pattern Recognition · Computer Science 2018-07-19 Carlo Biffi , Ozan Oktay , Giacomo Tarroni , Wenjia Bai , Antonio De Marvao , Georgia Doumou , Martin Rajchl , Reem Bedair , Sanjay Prasad , Stuart Cook , Declan O'Regan , Daniel Rueckert

Radiomics is an active area of research focusing on high throughput feature extraction from medical images with a wide array of applications in clinical practice, such as clinical decision support in oncology. However, noise in low dose…

Quantitative Methods · Quantitative Biology 2021-09-07 Junhua Chen , Inigo Bermejo , Andre Dekker , Leonard Wee

Automating arrhythmia detection from ECG requires a robust and trusted system that retains high accuracy under electrical disturbances. Many machine learning approaches have reached human-level performance in classifying arrhythmia from…

Signal Processing · Electrical Eng. & Systems 2022-10-14 Khondker Fariha Hossain , Sharif Amit Kamran , Alireza Tavakkoli , Xingjun Ma

The reconstruction kernel in computed tomography (CT) generation determines the texture of the image. Consistency in reconstruction kernels is important as the underlying CT texture can impact measurements during quantitative image…

We present a novel algorithm that is able to classify COVID-19 pneumonia from CT Scan slices using a very small sample of training images exhibiting COVID-19 pneumonia in tandem with a larger number of normal images. This algorithm is able…

Image and Video Processing · Electrical Eng. & Systems 2021-10-06 Sumeet Menon , Jayalakshmi Mangalagiri , Josh Galita , Michael Morris , Babak Saboury , Yaacov Yesha , Yelena Yesha , Phuong Nguyen , Aryya Gangopadhyay , David Chapman

Conditional generative adversarial networks (cGANs) have gained a considerable attention in recent years due to its class-wise controllability and superior quality for complex generation tasks. We introduce a simple yet effective approach…

Machine Learning · Computer Science 2019-10-22 Sangwoo Mo , Chiheon Kim , Sungwoong Kim , Minsu Cho , Jinwoo Shin

Coronary calcium causes beam hardening and blooming artifacts on cardiac computed tomography angiography (CTA) images, which lead to overestimation of lumen stenosis and reduction of diagnostic specificity. To properly remove coronary…

Computer Vision and Pattern Recognition · Computer Science 2018-03-02 Siming Yan , Feng Shi , Yuhua Chen , Damini Dey , Sang-Eun Lee , Hyuk-Jae Chang , Debiao Li , Yibin Xie

Recurrence risk estimation in clear cell renal cell carcinoma (ccRCC) is essential for guiding postoperative surveillance and treatment. The Leibovich score remains widely used for stratifying distant recurrence risk but offers limited…

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