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Related papers: Generative Models for Reproducible Coronary Calciu…

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Cardiovascular disease causes high rates of mortality worldwide. Coronary artery calcium (CAC) scoring is a powerful tool to stratify the risk of atherosclerotic cardiovascular disease. Current scoring practices require time-intensive…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Lachlan Nguyen , Aidan Cousins , Arcot Sowmya , Hugh Dixson , Sonit Singh

Coronary artery calcium (CAC) is a significant marker of atherosclerosis and cardiovascular events. In this work we present a system for the automatic quantification of calcium score in ECG-triggered non-contrast enhanced cardiac computed…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 G. Santini , D. Della Latta , N. Martini , G. Valvano , A. Gori , A. Ripoli , C. L. Susini , L. Landini , D. Chiappino

Cardiovascular disease (CVD) is the global leading cause of death. A strong risk factor for CVD events is the amount of coronary artery calcium (CAC). To meet demands of the increasing interest in quantification of CAC, i.e. coronary…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Bob D. de Vos , Jelmer M. Wolterink , Tim Leiner , Pim A. de Jong , Nikolas Lessmann , Ivana Isgum

Coronary artery calcium (CAC) is highly predictive of cardiovascular events. While millions of chest CT scans are performed annually in the United States, CAC is not routinely quantified from scans done for non-cardiac purposes. A deep…

Coronary artery calcium (CAC) is biomarker of advanced subclinical coronary artery disease and predicts myocardial infarction and death prior to age 60 years. The slice-wise manual delineation has been regarded as the gold standard of…

Computer Vision and Pattern Recognition · Computer Science 2018-11-13 Yuankai Huo , James G. Terry , Jiachen Wang , Vishwesh Nath , Camilo Bermudez , Shunxing Bao , Prasanna Parvathaneni , J. Jeffery Carr , Bennett A. Landman

Coronary artery calcium (CAC) scoring is a key predictor of cardiovascular risk, but it relies on ECG-gated CT scans, restricting its use to specialized cardiac imaging settings. We introduce an automated framework for CAC detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Mahmut S. Gokmen , Moneera N. Haque , Steve W. Leung , Caroline N. Leach , Seth Parker , Stephen B. Hobbs , Vincent L. Sorrell , W. Brent Seales , V. K. Cody Bumgardner

Coronary artery calcium (CAC) scoring plays a crucial role in the early detection and risk stratification of coronary artery disease (CAD). In this study, we focus on non-contrast coronary computed tomography angiography (CCTA) scans, which…

Non-contrast computed tomography calcium scoring (CTCS) is widely recognized as an effective tool for cardiovascular risk stratification. This study aimed to develop a novel machine learning framework for predicting myocardial ischemia from…

Machine Learning · Computer Science 2026-05-22 Juhwan Lee , Sadeer Al-Kindi , Ammar Hoori , Tao Hu , Hao Wu , Justin N. Kim , Robert Gilkeson , Sanjay Rajagopalan , David L. Wilson

Background. Coronary artery calcium (CAC) is a powerful predictor of major adverse cardiovascular events (MACE). Traditional Agatston score simply sums the calcium, albeit in a non-linear way, leaving room for improved calcification…

Quantitative Methods · Quantitative Biology 2023-08-24 Ammar Hoori , Sadeer Al-Kindi , Tao Hu , Yingnan Song , Hao Wu , Juhwan Lee , Nour Tashtish , Pingfu Fu , Robert Gilkeson , Sanjay Rajagopalan , David L. Wilson

Non-contrast computed tomography calcium scoring (CTCS) is a cost-effective imaging modality widely used to detect coronary artery calcifications. This study aimed to develop an advanced machine learning framework that utilizes quantitative…

As a potential non-invasive biomarker for ischaemic stroke, intracranial arterial calcification (IAC) could be used for stroke risk assessment on CT head scans routinely acquired for other reasons (e.g. trauma, confusion). Artificial…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Benjamin Jin , Maria del C. Valdés Hernández , Alessandro Fontanella , Wenwen Li , Eleanor Platt , Paul Armitage , Amos Storkey , Joanna M. Wardlaw , Grant Mair

Coronary artery calcium (CAC) burden quantified in low-dose chest CT is a predictor of cardiovascular events. We propose an automatic method for CAC quantification, circumventing intermediate segmentation of CAC. The method determines a…

Computer Vision and Pattern Recognition · Computer Science 2017-12-11 Bob D. de Vos , Nikolas Lessmann , Pim A. de Jong , Max A. Viergever , Ivana Isgum

Cardiovascular disease (CVD) is a common and strong threat to human beings, featuring high prevalence, disability and mortality. The amount of coronary artery calcification (CAC) is an effective factor for CVD risk evaluation.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-29 Jiechao Ma , Rongguo Zhang

Incidental detection and quantification of coronary calcium in CT scans could lead to the early introduction of lifesaving clinical interventions. However, over-reporting could negatively affect patient wellbeing and unnecessarily burden…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Olivier Jaubert , Salman Mohammadi , Keith A. Goatman , Shadia S. Mikhael , Conor Bradley , Rebecca Hughes , Richard Good , John H. Hipwell , Sonia Dahdouh

Coronary artery calcium (CAC) scoring from chest CT is a well-established tool to stratify and refine clinical cardiovascular disease risk estimation. CAC quantification relies on the accurate delineation of calcified lesions, but is…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Xinran Gong , Gorkem Durak , Halil Ertugrul Aktas , Vedat Cicek , Jinkui Hao , Ulas Bagci , Nilay S. Shah , Bo Zhou

Coronary artery calcification (CAC) is a strong predictor of cardiovascular events, with CT-based Agatston scoring widely regarded as the clinical gold standard. However, CT is costly and impractical for large-scale screening, while chest…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Dylan Saeed , Ramtin Gharleghi , Susann Beier , Sonit Singh

Aims. To develop a deep-learning based system for recognition of subclinical atherosclerosis on a plain frontal chest x-ray. Methods and Results. A deep-learning algorithm to predict coronary artery calcium (CAC) score (the AI-CAC model)…

We investigated the feasibility and advantages of using non-contrast CT calcium score (CTCS) images to assess pericoronary adipose tissue (PCAT) and its association with major adverse cardiovascular events (MACE). PCAT features from…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Yingnan Song , Hao Wu , Juhwan Lee , Justin Kim , Ammar Hoori , Tao Hu , Vladislav Zimin , Mohamed Makhlouf , Sadeer Al-Kindi , Sanjay Rajagopalan , Chun-Ho Yun , Chung-Lieh Hung , David L. Wilson

Every year, thousands of innocent people die due to heart attacks. Often undiagnosed heart attacks can hit people by surprise since many current medical plans don't cover the costs to require the searching of calcification on these scans.…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Sanskriti Singh

Coronary artery calcification (CAC) is a strong predictor of cardiovascular risk but remains underutilized in clinical routine thoracic imaging due to the need for dedicated imaging protocols and manual annotation. We present DeepCAC2, a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-27 Leonard Nürnberg , Simon Bernatz , Borek Foldyna , Michael T. Lu , Andrey Fedorov , Hugo JWL Aerts
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