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Cone Beam CT plays an important role in many medical fields nowadays, but the potential of this imaging modality is hampered by lower image quality compared to the conventional CT. A lot of recent research has been directed towards…

Medical Physics · Physics 2023-11-01 Nikita Moriakov , Jan-Jakob Sonke , Jonas Teuwen

Low-dose computed tomography (LDCT) plays a vital role in clinical applications by mitigating radiation risks. Nevertheless, reducing radiation doses significantly degrades image quality. Concurrently, common deep learning methods demand…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Wenhao Zhang , Bin Huang , Shuyue Chen , Xiaoling Xu , Weiwen Wu , Qiegen Liu

Since 2016, deep learning (DL) has advanced tomographic imaging with remarkable successes, especially in low-dose computed tomography (LDCT) imaging. Despite being driven by big data, the LDCT denoising and pure end-to-end reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2023-03-28 Wenjun Xia , Hongming Shan , Ge Wang , Yi Zhang

Medical imaging is playing a more and more important role in clinics. However, there are several issues in different imaging modalities such as slow imaging speed in MRI, radiation injury in CT and PET. Therefore, accelerating MRI, reducing…

Computer Vision and Pattern Recognition · Computer Science 2019-09-06 Jing Cheng , Haifeng Wang , Yanjie Zhu , Qiegen Liu , Qiyang Zhang , Ting Su , Jianwei Chen , Yongshuai Ge , Zhanli Hu , Xin Liu , Hairong Zheng , Leslie Ying , Dong Liang

Assume you encounter an inverse problem that shall be solved for a large number of data, but no ground-truth data is available. To emulate this encounter, in this study, we assume it is unknown how to solve the imaging problem of Computed…

Reconstructing 3D cone beam computed tomography (CBCT) images from a limited set of projections is an important inverse problem in many imaging applications from medicine to inertial confinement fusion (ICF). The performance of traditional…

Image and Video Processing · Electrical Eng. & Systems 2025-10-06 Xiaojian Xu , Marc Klasky , Michael T. McCann , Jason Hu , Jeffrey A. Fessler

Recent years have witnessed growing interest in machine learning-based models and techniques for low-dose X-ray CT (LDCT) imaging tasks. The methods can typically be categorized into supervised learning methods and unsupervised or…

Machine Learning · Computer Science 2019-10-29 Zhipeng Li , Siqi Ye , Yong Long , Saiprasad Ravishankar

Computed Tomography (CT) imaging technique is widely used in geological exploration, medical diagnosis and other fields. In practice, however, the resolution of CT image is usually limited by scanning devices and great expense. Super…

Computer Vision and Pattern Recognition · Computer Science 2020-01-29 Yukai Wang , Qizhi Teng , Xiaohai He , Junxi Feng , Tingrong Zhang

Reconstructing dynamic, time-varying scenes with computed tomography (4D-CT) is a challenging and ill-posed problem common to industrial and medical settings. Existing 4D-CT reconstructions are designed for sparse sampling schemes that…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Albert W. Reed , Hyojin Kim , Rushil Anirudh , K. Aditya Mohan , Kyle Champley , Jingu Kang , Suren Jayasuriya

Purpose: To investigate whether synthetically generated fractal data can be used to train deep learning (DL) models for dynamic MRI reconstruction, thereby avoiding the privacy, licensing, and availability limitations associated with…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Anirudh Raman , Olivier Jaubert , Mark Wrobel , Tina Yao , Ruaraidh Campbell , Rebecca Baker , Ruta Virsinskaite , Daniel Knight , Michael Quail , Jennifer Steeden , Vivek Muthurangu

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent application of deep learning methods for image reconstruction provides a successful data-driven approach to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-22 Ling Chen , Zhishen Huang , Yong Long , Saiprasad Ravishankar

Histologic examination plays a crucial role in oncology research and diagnostics. The adoption of digital scanning of whole slide images (WSI) has created an opportunity to leverage deep learning-based image classification methods to…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Md Zahangir Alom , Quynh T. Tran , Brent A. Orr

Computed tomography (CT) is a widely used non-invasive diagnostic method in various fields, and recent advances in deep learning have led to significant progress in CT image reconstruction. However, the lack of large-scale, open-access…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Maximilian B. Kiss , Ander Biguri , Zakhar Shumaylov , Ferdia Sherry , K. Joost Batenburg , Carola-Bibiane Schönlieb , Felix Lucka

A major challenge in X-ray computed tomography (CT) is reducing radiation dose while maintaining high quality of reconstructed images. To reduce the radiation dose, one can reduce the number of projection views (sparse-view CT); however, it…

Machine Learning · Statistics 2019-09-17 Xuehang Zheng , Il Yong Chun , Zhipeng Li , Yong Long , Jeffrey A. Fessler

Spectral Photon-Counting Computed Tomography (SPCCT) is a promising technology that has shown a number of advantages over conventional X-ray Computed Tomography (CT) in the form of material separation, artefact removal and enhanced image…

Image and Video Processing · Electrical Eng. & Systems 2020-03-10 Dimitris Kamilis , Mario Blatter , Nick Polydorides

Computed tomography (CT) is widely used in screening, diagnosis, and image-guided therapy for both clinical and research purposes. Since CT involves ionizing radiation, an overarching thrust of related technical research is development of…

Image and Video Processing · Electrical Eng. & Systems 2019-06-25 Chenyu You , Guang Li , Yi Zhang , Xiaoliu Zhang , Hongming Shan , Shenghong Ju , Zhen Zhao , Zhuiyang Zhang , Wenxiang Cong , Michael W. Vannier , Punam K. Saha , Ge Wang

Low-dose CT (LDCT) imaging attracted a considerable interest for the reduction of the object's exposure to X-ray radiation. In recent years, supervised deep learning (DL) has been extensively studied for LDCT image reconstruction, which…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Qiaoqiao Ding , Hui Ji , Yuhui Quan , Xiaoqun Zhang

Magnetic resonance imaging (MRI) is known to be a slow imaging modality and undersampling in k-space has been used to increase the imaging speed. However, image reconstruction from undersampled k-space data is an ill-posed inverse problem.…

Image and Video Processing · Electrical Eng. & Systems 2019-08-08 Jing Cheng , Haifeng Wang , Leslie Ying , Dong Liang

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

X-ray computed tomography (CT) reconstructs cross-sectional images from projection data. However, ionizing X-ray radiation associated with CT scanning might induce cancer and genetic damage. Therefore, the reduction of radiation dose has…

Image and Video Processing · Electrical Eng. & Systems 2019-09-13 Huidong Xie , Hongming Shan , Wenxiang Cong , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Ge Wang