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Evolution is a process that is influenced by various environmental factors, e.g. the interactions between different species, genes, and biogeographical properties. Hence, it is interesting to study the combined evolutionary history of…

Quantitative Methods · Quantitative Biology 2013-08-02 Nicolas Wieseke , Matthias Bernt , Martin Middendorf

Significant phylogenetic codivergence between plant or animal hosts ($H$) and their symbionts or parasites ($P$) indicate the importance of their interactions on evolutionary time scales. However, valid and realistic methods to test for…

Populations and Evolution · Quantitative Biology 2008-08-28 Chris L. Schardl , Kelly D. Craven , Adam Lindstrom , Skyler Speakman , Arnold Stromberg , Ruriko Yoshida

The reconstruction of a species phylogeny from genomic data faces two significant hurdles: 1) the trees describing the evolution of each individual gene--i.e., the gene trees--may differ from the species phylogeny and 2) the molecular…

Machine Learning · Computer Science 2017-07-17 Gautam Dasarathy , Elchanan Mossel , Robert Nowak , Sebastien Roch

Gene trees record the combination of gene level events, such as duplication, transfer and loss, and species level events, such as speciation and extinction. Gene tree-species tree reconciliation methods model these processes by drawing gene…

Populations and Evolution · Quantitative Biology 2013-06-11 Gergely J. Szöllősi , Wojciech Rosikiewicz , Bastien Boussau , Eric Tannier , Vincent Daubin

Traditionally, phylogeny and sequence alignment are estimated separately: first estimate a multiple sequence alignment and then infer a phylogeny based on the sequence alignment estimated in the previous step. However, uncertainty in the…

Applications · Statistics 2014-11-25 Heejung Shim , Bret Larget

Predicting protein-protein interactions from sequences is an important goal of computational biology. Various sources of information can be used to this end. Starting from the sequences of two interacting protein families, one can use…

Biomolecules · Quantitative Biology 2023-04-26 Carlos A. Gandarilla-Perez , Sergio Pinilla , Anne-Florence Bitbol , Martin Weigt

Phylogenetic reconciliation seeks to explain host-symbiont co-evolution by mapping parasite trees onto host trees through events such as cospeciation, duplication, host switching, and loss. Finding an optimal reconciliation that ensures…

Populations and Evolution · Quantitative Biology 2026-02-02 Cyriac Antony , Alessio Martino , Blerina Sinaimeri

Topologically constrained genome-like polymers often double-fold into tree-like configurations, which can be modelled on the level of folded (ring) polymers or on the level of the underlying random trees. For both descriptions, we have…

Soft Condensed Matter · Physics 2026-05-19 Pieter H. W. van der Hoek , Angelo Rosa , Elham Ghobadpour , Ralf Everaers

Phylogenetic comparative methods (PCMs) are widely used to study trait evolution. However, many evolutionary histories involve reticulate evolutionary scenarios, such as hybridization, that violate core assumptions of these methods. In this…

Populations and Evolution · Quantitative Biology 2026-03-30 Lydia Morley , Emma Lehmberg , Sungsik Kong

Comparative and evolutive ecologists are interested in the distribution of quantitative traits among related species. The classical framework for these distributions consists of a random process running along the branches of a phylogenetic…

Applications · Statistics 2017-08-24 Paul Bastide , Mahendra Mariadassou , Stéphane Robin

Recently, much attention has been given to understanding recombination events along a chromosome in a variety of field. For instance, many population genetics problems are limited by the inaccuracy of inferred evolutionary histories of…

Quantitative Methods · Quantitative Biology 2017-10-31 Jacqueline Kane , Joseph Rusinko , Katherine Thompson

Reconciling a gene tree with a species tree is an important task that reveals much about the evolution of genes, genomes, and species, as well as about the molecular function of genes. A wide array of computational tools have been devised…

Populations and Evolution · Quantitative Biology 2012-12-11 Yun Yu , Luay Nakhleh

Phylogenetic trees are pervasively used to depict evolutionary relationships. Increasingly, researchers need to visualize large trees and compare multiple large trees inferred for the same set of taxa (reflecting uncertainty in the tree…

Populations and Evolution · Quantitative Biology 2016-04-21 Oscar Robinson , David Dylus , Christophe Dessimoz

The nature inspired algorithms are becoming popular due to their simplicity and wider applicability. In the recent past several such algorithms have been developed. They are mainly bio-inspired, swarm based, physics based and…

Neural and Evolutionary Computing · Computer Science 2025-03-13 Anand J Kulkarni , Isha Purnapatre , Apoorva S Shastri

Reconciling gene trees with a species tree is a fundamental problem to understand the evolution of gene families. Many existing approaches reconcile each gene tree independently. However, it is well-known that the evolution of gene families…

Populations and Evolution · Quantitative Biology 2018-06-12 Riccardo Dondi , Manuel Lafond , Celine Scornavacca

Under the multispecies coalescent model of molecular evolution, gene trees have independent evolutionary histories within a shared species tree. In comparison, supermatrix concatenation methods assume that gene trees share a single common…

Populations and Evolution · Quantitative Biology 2016-06-13 Huw A. Ogilvie , Joseph Heled , Dong Xie , Alexei J. Drummond

We introduce a hybrid metaphor for the visualization of the reconciliations of co-phylogenetic trees, that are mappings among the nodes of two trees. The typical application is the visualization of the co-evolution of hosts and parasites in…

Data Structures and Algorithms · Computer Science 2017-09-01 Tiziana Calamoneri , Valentino Di Donato , Diego Mariottini , Maurizio Patrignani

Phylogenetic networks are a generalization of phylogenetic trees that allow for the representation of evolutionary events acting at the population level, like recombination between genes, hybridization between lineages, and lateral gene…

Populations and Evolution · Quantitative Biology 2007-11-26 Gabriel Cardona , Francesc Rossello , Gabriel Valiente

Phylogenetic trees describe the relationships between species in the evolutionary process, and provide information about the rates of diversification. To understand the mechanisms behind macroevolution, we consider a class of multitype…

Populations and Evolution · Quantitative Biology 2024-10-07 Mingqi He , Sophie Hautphenne , Yao-ban Chan

The multispecies coalescent process models the genealogical relationships of genes sampled from several species, enabling useful predictions about phenomena such as the discordance between the gene tree and the species phylogeny due to…

Populations and Evolution · Quantitative Biology 2020-12-11 Jakub Truszkowski , Celine Scornavacca , Fabio Pardi
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