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Backpropagation is the core learning mechanism underlying deep learning. However, whether and how this algorithm is implemented in the brain remains highly debated. In particular, while forward activations of pretrained models reliably map…

Both biological cortico-thalamic networks and artificial transformer networks use canonical computations to perform a wide range of cognitive tasks. In this work, we propose that the structure of cortico-thalamic circuits is well suited to…

Neurons and Cognition · Quantitative Biology 2025-08-12 Arno Granier , Walter Senn

Accurate automatic tissue segmentation in fetal brain MRI is a crucial step in clinical diagnosis but remains challenging, particularly due to the dynamically changing anatomy and tissue contrast during fetal development. Existing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-12 Haoan Xu , Tianshu Zheng , Xinyi Xu , Yao Shen , Jiwei Sun , Cong Sun , Guangbin Wang , Zhaopeng Cui , Dan Wu

Visual attention mechanisms have proven to be integrally important constituent components of many modern deep neural architectures. They provide an efficient and effective way to utilize visual information selectively, which has shown to be…

Computer Vision and Pattern Recognition · Computer Science 2019-05-24 Siddhesh Khandelwal , Leonid Sigal

Mammalian functional architecture flexibly adapts, transitioning from integration where information is distributed across the cortex, to segregation where information is focal in densely connected communities of brain regions. This…

Neurons and Cognition · Quantitative Biology 2025-04-03 Kimberly Nestor

The reconstruction of cerebral cortex surfaces from brain MRI scans is instrumental for the analysis of brain morphology and the detection of cortical thinning in neurodegenerative diseases like Alzheimer's disease (AD). Moreover, for a…

Neurons and Cognition · Quantitative Biology 2022-10-05 Anne-Marie Rickmann , Fabian Bongratz , Sebastian Pölsterl , Ignacio Sarasua , Christian Wachinger

Cortical folding exhibits substantial inter-individual variability while preserving stable anatomical landmarks that enable fine-scale characterization of cortical organization. Among these, the three-hinge gyrus (3HG) serves as a key…

Neurons and Cognition · Quantitative Biology 2026-02-03 Minheng Chen , Tong Chen , Yan Zhuang , Chao Cao , Jing Zhang , Tianming Liu , Lu Zhang , Dajiang Zhu

Multi-modal neuroimaging technology has greatlly facilitated the efficiency and diagnosis accuracy, which provides complementary information in discovering objective disease biomarkers. Conventional deep learning methods, e.g. convolutional…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Yanwu Yang , Xutao Guo , Zhikai Chang , Chenfei Ye , Yang Xiang , Ting Ma

Understanding how brain structure and function interact is key to explaining intelligence yet modeling them jointly is challenging as the structural and functional connectome capture complementary aspects of organization. We introduced…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Badhan Mazumder , Sir-Lord Wiafe , Aline Kotoski , Vince D. Calhoun , Dong Hye Ye

Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time because morphological changes in these structures are related to different neurodegenerative…

Computer Vision and Pattern Recognition · Computer Science 2018-11-15 Kaisar Kushibar , Sergi Valverde , Sandra Gonzalez-Villa , Jose Bernal , Mariano Cabezas , Arnau Oliver , Xavier Llado

Graph neural networks (GNNs) have been successfully applied to early mild cognitive impairment (EMCI) detection, with the usage of elaborately designed features constructed from blood oxygen level-dependent (BOLD) time series. However, few…

Machine Learning · Computer Science 2022-11-14 Yunpeng Zhao , Fugen Zhou , Bin Guo , Bo Liu

Network analysis is rapidly becoming a standard tool for studying functional magnetic resonance imaging (fMRI) data. In this framework, different brain areas are mapped to the nodes of a network, whose links depict functional dependencies…

Neurons and Cognition · Quantitative Biology 2017-05-30 Rainer Kujala , Enrico Glerean , Raj Kumar Pan , Iiro P. Jääskeläinen , Mikko Sams , Jari Saramäki

In skeleton-based action recognition, Graph Convolutional Networks model human skeletal joints as vertices and connect them through an adjacency matrix, which can be seen as a local attention mask. However, in most existing Graph…

Computer Vision and Pattern Recognition · Computer Science 2022-07-13 Hao Xing , Darius Burschka

We propose a framework for jointly modeling the geometry and functionality in high dimensional functional surfaces. The proposed mixed effects model characterizes effects of subject-specific covariates and exogenous stimuli on functional…

Applications · Statistics 2023-02-10 Jingjing Zou , Chi-Hua Chen , John A. D. Aston

Understanding the complex neural activity dynamics is crucial for the development of the field of neuroscience. Although current functional MRI classification approaches tend to be based on static functional connectivity or cannot capture…

Machine Learning · Computer Science 2025-08-20 Amirali Arbab , Zeinab Davarani , Mehran Safayani

Neuronal cell bodies mostly reside in the cerebral cortex. The study of this thin and highly convoluted surface is essential for understanding how the brain works. The analysis of surface data is, however, challenging due to the high…

Computer Vision and Pattern Recognition · Computer Science 2018-03-29 Karthik Gopinath , Christian Desrosiers , Herve Lombaert

Functional magnetic resonance imaging (fMRI) is a neuroimaging technique known for its ability to capture brain activity non-invasively and at fine spatial resolution (2-3mm). Cortical surface fMRI (cs-fMRI) is a recent development of fMRI…

Applications · Statistics 2023-12-29 Huy Dang , Marzia Cremona , Nicole Lazar , Francesca Chiaromonte

Objective: Multi-modal functional magnetic resonance imaging (fMRI) can be used to make predictions about individual behavioral and cognitive traits based on brain connectivity networks. Methods: To take advantage of complementary…

Machine Learning · Computer Science 2024-08-27 Gang Qu , Li Xiao , Wenxing Hu , Kun Zhang , Vince D. Calhoun , Yu-Ping Wang

We present an attention-based spatial graph convolution (AGC) for graph neural networks (GNNs). Existing AGCs focus on only using node-wise features and utilizing one type of attention function when calculating attention weights. Instead,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Yang Li , Yuichi Tanaka

In neuroscience, understanding inter-individual differences has recently emerged as a major challenge, for which functional magnetic resonance imaging (fMRI) has proven invaluable. For this, neuroscientists rely on basic methods such as…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Akrem Sellami , François-Xavier Dupé , Bastien Cagna , Hachem Kadri , Stéphane Ayache , Thierry Artières , Sylvain Takerkart