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Genetic engineering of cells has a range of applications in treating incurable diseases. Plasmid DNA is a popular choice of nucleic acid for cell engineering due to its low cost and stability. However, plasmid DNA must survive the…

Biological Physics · Physics 2025-10-06 Leyla Akh , Apresio K. Fajrial , Benjamin Seelbinder , Xin Xu , Wei Tan , Jill Slansky , Corey P. Neu , Xiaoyun Ding

Laser flash melting and revitrification experiments have recently improved the time resolution of cryo-electron microscopy (cryo-EM) to the microsecond timescale, making it fast enough to observe many of the protein motions that are…

Instrumentation and Detectors · Physics 2026-05-19 Wyatt A. Curtis , Constantin R. Krüger , Axel P. Tracol Gavard , Jakub Wenz , Marcel Drabbels , Ulrich J. Lorenz

This study investigates the shock-induced atomisation dynamics of an acoustically levitated TM-10 nanofluid droplet subjected to a coaxially propagating blast wave and subsequent compressible vortex ring, generated using a compact…

Fluid Dynamics · Physics 2025-08-21 Gautham Vadlamudi , Bal Krishan , Akarsh Choudhary , Saptarshi Basu

We combined experimental and theoretical investigations of an effective two-level atomic system operating in the near-infrared telecom wavelength regime, realized using hot rubidium vapor confined within a sub-micron-thick cell. In this…

Quantum Physics · Physics 2026-01-26 Gilad Orr , Golan Ben-Ari , Eliran Talker

The spectroscopy of free radicals and radical containing entrance-channel complexes embedded in superfluid helium nano-droplets is reviewed. The collection of dopants inside individual droplets in the beam represents a micro-canonical…

Atomic and Molecular Clusters · Physics 2007-08-02 Jochen Küpper , Jeremy M. Merritt

We report on fabrication of whispering-gallery-mode microlasers in a Nd:glass chip by femtosecond laser three-dimensional (3D) micromachining. Main fabrication procedures include the fabrication of freestanding microdisks supported by thin…

We present the design and implementation of a new, modular gas target suitable for high-order harmonic generation using high average power lasers. To ensure thermal stability in this high heat load environment, we implement an appropriate…

Laser-induced cavitation under nanosecond optical breakdown is central to applications such as laser-induced forward transfer, microsurgery, and microfluidic actuation, yet the physical origin of the earliest cavity and its connection to…

Fluid Dynamics · Physics 2026-05-25 Shuqi Zhou , Abdol Hadi Mokarizadeh , Ben Xu

A high vacuum gate valve for skimmed molecular beam experiments is described. It is designed with a very short extent of only 10 mm along the molecular beam axis to minimize the distance between the molecular beam source and the experiment…

Instrumentation and Detectors · Physics 2009-09-29 Jochen Küpper , Henrik Haak , Kirstin Wohlfart , Gerard Meijer

Separation is a crucial step in the analysis of living microparticles. In particular, the selective microseparation of phytoplankton by size and shape remains an open problem, even though these criteria are essential for their gender and/or…

Applied Physics · Physics 2025-04-09 Nicolas Ruyssen , Bastien Oliva , Lylian Challier , Vincent Noël , Benjamin Rotenberg

Deterministic and versatile approaches to sample preparation on nanoscopic scales are important in many fields including photonics, electronics, biology and material science. However, challenges exist in meeting many nanostructuring…

Atomic sensors employing cold-atom technology enable unprecedented accuracy and resolution for next generation atomic clocks, magnetometers, gravimeters, and gyroscopes. To date, however, the size and complexity of cold atom systems have…

Atomic Physics · Physics 2011-11-28 Vishal Shah , Mark Mescher , Rick Stoner , Vladan Vuletic , Robert Lutwak

A novel method to pump fluid in lab on chip devices with velocities up to tens of micrometer per second is introduced. A focused laser beam locally heats up an electrolyte. A net charge tends to accumulate in the heat-absorbing area, due to…

Soft Condensed Matter · Physics 2014-05-08 Reza Kiani Iranpour , Seyyed Nader Rasuli

Fiber-integrated micro-optical elements promise a scalable approach to photon collection and beam shaping for quantum information processing. Here, we demonstrate single-step fabrication of micro-spherical, micro-spiral, and micro-axicon…

Optics · Physics 2026-04-21 Raman Kumar , Sebastian Will

We report on the realisation of a chip-based multipole ion trap manufactured using micro-electromechanical systems (MEMS) technology. It provides ion confinement in an almost field-free volume between two planes of radiofrequency…

We demonstrate and interpret a technique of laser-induced formation of thin metallic films using alkali atoms on the window of a dense-vapour cell. We show that this intriguing photo-stimulated process originates from the adsorption of Cs…

Machine learning-based interatomic potentials and force fields depend critically on accurate atomic structures, yet such data are scarce due to the limited availability of experimentally resolved crystals. Although atomic-resolution…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Yaotian Yang , Yiwen Tang , Yizhe Chen , Xiao Chen , Jiangjie Qiu , Hao Xiong , Haoyu Yin , Zhiyao Luo , Yifei Zhang , Sijia Tao , Wentao Li , Qinghua Zhang , Yuqiang Li , Wanli Ouyang , Bin Zhao , Xiaonan Wang , Fei Wei

Interfacing cold atoms with integrated nanophotonic devices could offer new paradigms for engineering atom-light interactions and provide a potentially scalable route for quantum sensing, metrology, and quantum information processing.…

Quantum Physics · Physics 2024-07-26 Xinchao Zhou , Hikaru Tamura , Tzu-Han Chang , Chen-Lung Hung

Droplet microfluidics are a powerful approach for hydrogel cell encapsulations. Much of the field has focused on single-cell encapsulations with pico-nanoliter droplet volumes necessary for single-cell sequencing or high-throughput…

We propose an architecture and methodology for large-scale quantum simulations using hyperfine states of trapped-ions in an arbitrary-layout microtrap array with laserless interactions. An ion is trapped at each site, and the electrode…

Quantum Physics · Physics 2008-03-13 J. Chiaverini , W. E. Lybarger