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Monitoring the biomedical literature for cases of Adverse Drug Reactions (ADRs) is a critically important and time consuming task in pharmacovigilance. The development of computer assisted approaches to aid this process in different forms…

Computation and Language · Computer Science 2018-04-25 Diego Saldana Miranda

Robust control of mechanical systems with multiple uncertainties remains a fundamental challenge, particularly when nonlinear dynamics and operating-condition variations are intricately intertwined. Although deep reinforcement learning…

Machine Learning · Computer Science 2026-03-11 Heisei Yonezawa , Ansei Yonezawa , Itsuro Kajiwara

Dynamic treatment regimes (DTRs) formalize medical decision-making as a sequence of rules for different stages, mapping patient-level information to recommended treatments. In practice, estimating an optimal DTR using observational data…

Methodology · Statistics 2024-12-11 Jian Sun , Bo Fu , Li Su

Artificial intelligence and distributed algorithms have been widely used in mechanical fault diagnosis with the explosive growth of diagnostic data. A novel intelligent fault diagnosis system framework that allows intelligent terminals to…

Information Theory · Computer Science 2023-02-16 Liang Yu , Qixin Guo , Rui Wang , Minyan Shi , Fucheng Yan , Ran Wang

Entropy regularization is a popular method in reinforcement learning (RL). Although it has many advantages, it alters the RL objective of the original Markov Decision Process (MDP). Though divergence regularization has been proposed to…

Machine Learning · Computer Science 2022-06-22 Kefan Su , Zongqing Lu

Dwell time (DT) is a critical post-click metric for evaluating user preference in recommender systems, complementing the traditional click-through rate (CTR). Although multi-task learning is widely adopted to jointly optimize DT and CTR, we…

Information Retrieval · Computer Science 2025-08-25 Huishi Luo , Fuzhen Zhuang , Yongchun Zhu , Yiqing Wu , Bo Kang , Ruobing Xie , Feng Xia , Deqing Wang , Jin Dong

In recent years, research interest in personalised treatments has been growing. However, treatment effect heterogeneity and possibly time-varying treatment effects are still often overlooked in clinical studies. Statistical tools are needed…

Methodology · Statistics 2023-10-27 Caterina Gregorio , Giovanni Baj , Giulia Barbati , Francesca Ieva

Individualized treatment rules/recommendations (ITRs) aim to improve patient outcomes by tailoring treatments to the characteristics of each individual. However, when there are many treatment groups, existing methods face significant…

Methodology · Statistics 2025-05-27 Ke Zhu , Jianing Chu , Ilya Lipkovich , Wenyu Ye , Shu Yang

Understanding the effects of interventions is central to scientific progress, with randomized controlled trials (RCTs) regarded as the gold standard for causal inference in many applied fields. However, RCTs are costly, time-consuming, and…

Methodology · Statistics 2026-05-27 Drago Plecko , Patrik Okanovic , Torsten Hoefler , Elias Bareinboim

We present a Reinforcement Learning (RL) approach to the problem of controlling the Discontinuous Reception (DRX) policy from a Base Transceiver Station (BTS) in a cellular network. We do so by means of optimally timing the transmission of…

Information Theory · Computer Science 2024-06-21 Adriano Pastore , Adrián Agustín de Dios , Álvaro Valcarce

Autonomous assistance of people with motor impairments is one of the most promising applications of autonomous robotic systems. Recent studies have reported encouraging results using deep reinforcement learning (RL) in the healthcare…

Robotics · Computer Science 2024-04-02 Takayuki Osa , Tatsuya Harada

A key aspect of intelligence is the ability to demonstrate a broad spectrum of behaviors for adapting to unexpected situations. Over the past decade, advancements in deep reinforcement learning have led to groundbreaking achievements to…

Machine Learning · Computer Science 2024-06-04 Luca Grillotti , Maxence Faldor , Borja G. León , Antoine Cully

Tailoring treatment for individual patients is crucial yet challenging in order to achieve optimal healthcare outcomes. Recent advances in reinforcement learning offer promising personalized treatment recommendations; however, they rely…

Machine Learning · Computer Science 2023-07-06 Simin Ma , Junghwan Lee , Nicoleta Serban , Shihao Yang

Due to their expressive capacity, diffusion models have shown great promise in offline RL and imitation learning. Diffusion Actor-Critic with Entropy Regulator (DACER) extended this capability to online RL by using the reverse diffusion…

Reinforcement learning has attracted great attention recently, especially policy gradient algorithms, which have been demonstrated on challenging decision making and control tasks. In this paper, we propose an active multi-step TD algorithm…

Machine Learning · Computer Science 2019-11-28 Gang Chen , Dingcheng Li , Ran Xu

We study a class of structured optimal control problems in which the main diagonal of the dynamic matrix is a linear function of the design variable. While such problems are in general challenging and nonconvex, for positive systems we…

Optimization and Control · Mathematics 2019-07-09 Neil K. Dhingra , Marcello Colombino , Mihailo R. Jovanović

Reinforcement learning has been proven to be highly effective in handling complex control tasks. Traditional methods typically use unimodal distributions, such as Gaussian distributions, to model the output of value distributions. However,…

Machine Learning · Computer Science 2025-07-14 Tong Liu , Yinuo Wang , Xujie Song , Wenjun Zou , Liangfa Chen , Likun Wang , Bin Shuai , Jingliang Duan , Shengbo Eben Li

Sequential multiple assignment randomized trials (SMARTs) provide a systematic framework for constructing and evaluating dynamic treatment regimens (DTRs). In clinical studies, longitudinal biomarkers are routinely collected to monitor…

Methodology · Statistics 2026-05-06 Zhengxi Chen , Holly Hartman

Dynamic treatment regimes (DTRs) are personalized, adaptive strategies designed to guide the sequential allocation of treatments based on individual characteristics over time. Before each treatment assignment, covariate information is…

Methodology · Statistics 2025-07-24 Kai Chen , Yuqian Zhang

Diffusion policies trained via offline behavioral cloning have recently gained traction in robotic motion generation. While effective, these policies typically require a large number of trainable parameters. This model size affords powerful…

Robotics · Computer Science 2025-04-29 Xiatao Sun , Shuo Yang , Yinxing Chen , Francis Fan , Yiyan Liang , Daniel Rakita