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Quantitative characterization of disease progression using longitudinal data can provide long-term predictions for the pathological stages of individuals. This work studies the robust modeling of Alzheimer's disease progression using…

Semi-functional linear regression models postulate a linear relationship between a scalar response and a functional covariate, and also include a non-parametric component involving a univariate explanatory variable. It is of practical…

Methodology · Statistics 2023-08-08 Graciela Boente , Matias Salibian-Barrera , Pablo Vena

Classifiers built with neural networks handle large-scale high dimensional data, such as facial images from computer vision, extremely well while traditional statistical methods often fail miserably. In this paper, we attempt to understand…

Machine Learning · Statistics 2020-02-04 Tianyang Hu , Zuofeng Shang , Guang Cheng

This note introduces a doubly robust (DR) estimator for regression discontinuity (RD) designs. RD designs provide a quasi-experimental framework for estimating treatment effects, where treatment assignment depends on whether a running…

Econometrics · Economics 2025-01-28 Masahiro Kato

Robust estimation under Huber's $\epsilon$-contamination model has become an important topic in statistics and theoretical computer science. Statistically optimal procedures such as Tukey's median and other estimators based on depth…

Machine Learning · Statistics 2019-02-27 Chao Gao , Jiyi Liu , Yuan Yao , Weizhi Zhu

Disease progression modeling (DPM) using longitudinal data is a challenging machine learning task. Existing DPM algorithms neglect temporal dependencies among measurements, make parametric assumptions about biomarker trajectories, do not…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Mostafa Mehdipour Ghazi , Mads Nielsen , Akshay Pai , M. Jorge Cardoso , Marc Modat , Sebastien Ourselin , Lauge Sørensen

Activity recognition has become a popular research branch in the field of pervasive computing in recent years. A large number of experiments can be obtained that activity sensor-based data's characteristic in activity recognition is…

Computer Vision and Pattern Recognition · Computer Science 2018-05-21 Li Xue , Si Xiandong , Nie Lanshun , Li Jiazhen , Ding Renjie , Zhan Dechen , Chu Dianhui

Functional logistic regression is a popular model to capture a linear relationship between binary response and functional predictor variables. However, many methods used for parameter estimation in functional logistic regression are…

Methodology · Statistics 2025-10-15 Berkay Akturk , Ufuk Beyaztas , Han Lin Shang

Observational cohort studies are increasingly being used for comparative effectiveness research to assess the safety of therapeutics. Recently, various doubly robust methods have been proposed for average treatment effect estimation by…

Methodology · Statistics 2025-03-11 Xiaoqing Tan , Shu Yang , Wenyu Ye , Douglas E. Faries , Ilya Lipkovich , Zbigniew Kadziola

Recently, machine learning techniques especially predictive modeling and pattern recognition in biomedical sciences from drug delivery system to medical imaging has become one of the important methods which are assisting researchers to have…

Computer Vision and Pattern Recognition · Computer Science 2017-05-23 Saman Sarraf , Ghassem Tofighi

Activation functions influence behavior and performance of DNNs. Nonlinear activation functions, like Rectified Linear Units (ReLU), Exponential Linear Units (ELU) and Scaled Exponential Linear Units (SELU), outperform the linear…

Neural and Evolutionary Computing · Computer Science 2019-02-05 Alberto Marchisio , Muhammad Abdullah Hanif , Semeen Rehman , Maurizio Martina , Muhammad Shafique

Functional data analysis is a fast evolving branch of modern statistics and the functional linear model has become popular in recent years. However, most estimation methods for this model rely on generalized least squares procedures and…

Methodology · Statistics 2020-06-24 Ioannis Kalogridis , Stefan Van Aelst

We propose a deep neural network for supervised learning on neuroanatomical shapes. The network directly operates on raw point clouds without the need for mesh processing or the identification of point correspondences, as spatial…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Benjamin Gutierrez-Becker , Christian Wachinger

Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. Despite the many advantages of joint modeling, the standard forms suffer from limitations that arise…

Machine Learning · Statistics 2018-07-10 Bryan Lim , Mihaela van der Schaar

We study regularized estimation in high-dimensional longitudinal classification problems, using the lasso and fused lasso regularizers. The constructed coefficient estimates are piecewise constant across the time dimension in the…

Accurate diagnosis and prognosis of Alzheimer's disease are crucial to develop new therapies and reduce the associated costs. Recently, with the advances of convolutional neural networks, methods have been proposed to automate these two…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…

Image and Video Processing · Electrical Eng. & Systems 2022-08-11 Yongcheng Zong , Changhong Jing , Qiankun Zuo

Deep learning has been widely used in many fields, but the model training process usually consumes massive computational resources and time. Therefore, designing an efficient neural network training method with a provable convergence…

Machine Learning · Computer Science 2023-07-14 Lianke Qin , Zhao Song , Yuanyuan Yang

We derive an estimator of the spectral density of a functional time series that is the output of a multilayer perceptron neural network. The estimator is motivated by difficulties with the computation of existing spectral density estimators…

Methodology · Statistics 2026-01-05 Neda Mohammadi , Soham Sarkar , Piotr Kokoszka

With the development of convolution neural network, more and more researchers focus their attention on the advantage of CNN for face recognition task. In this paper, we propose a deep convolution network for learning a robust face…

Computer Vision and Pattern Recognition · Computer Science 2015-07-20 Xiang Wu
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