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We present an investigation of the applicability of topological data analysis (TDA) to the study of high-resolution confocal microscopy images of fibrin network structures from patients with oesophageal cancer undergoing intended curative…

Other Quantitative Biology · Quantitative Biology 2026-05-22 Thomas Burnett , Theresa Reinhold , Bea Bleile , Sophie Raynor , Freya Jensen , Martin Hermann , Tua Gyldenholm , Yossi Bokor Bleile

Convolutional neural networks (CNN's) are powerful and widely used tools. However, their interpretability is far from ideal. One such shortcoming is the difficulty of deducing a network's ability to generalize to unseen data. We use…

Computer Vision and Pattern Recognition · Computer Science 2019-10-21 Rickard Brüel Gabrielsson , Gunnar Carlsson

Topological data analysis is a relatively new branch of machine learning that excels in studying high dimensional data, and is theoretically known to be robust against noise. Meanwhile, data objects with mixed numeric and categorical…

Algebraic Topology · Mathematics 2020-06-15 Chengyuan Wu , Carol Anne Hargreaves

Topology identification and inference of processes evolving over graphs arise in timely applications involving brain, transportation, financial, power, as well as social and information networks. This chapter provides an overview of graph…

Signal Processing · Electrical Eng. & Systems 2025-12-12 Gonzalo Mateos , Yanning Shen , Georgios B. Giannakis , Ananthram Swami

We present a topological framework for analysing neural time series that integrates Transfer Entropy (TE) with directed Persistent Homology (PH) to characterize information flow in spiking neural systems. TE quantifies directional influence…

Neurons and Cognition · Quantitative Biology 2025-08-27 Dylan Peek , Siddharth Pritam , Matthew P. Skerritt , Stephan Chalup

We introduce an innovative, data-driven topological data analysis (TDA) technique for estimating the state spaces of dynamically changing functional human brain networks at rest. Our method utilizes the Wasserstein distance to measure…

Algebraic Topology · Mathematics 2024-04-18 Moo K. Chung , Shih-Gu Huang , Ian C. Carroll , Vince D. Calhoun , H. Hill Goldsmith

This work is devoted to a comprehensive analysis of topological data analysis fortime series classification. Previous works have significant shortcomings, such aslack of large-scale benchmarking or missing state-of-the-art methods. In this…

Machine Learning · Computer Science 2020-10-13 Polina Pilyugina , Rodrigo Rivera-Castro , Eugeny Burnaev

Recent advances in molecular representation learning have produced highly effective encodings of molecules for numerous cheminformatics and bioinformatics tasks. However, extracting general chemical insight while balancing predictive…

Machine Learning · Computer Science 2025-09-26 Rahul Khorana

Existing learning-based methods for solving job shop scheduling problems (JSSP) usually use off-the-shelf GNN models tailored to undirected graphs and neglect the rich and meaningful topological structures of disjunctive graphs (DGs). This…

Machine Learning · Computer Science 2024-06-06 Cong Zhang , Zhiguang Cao , Yaoxin Wu , Wen Song , Jing Sun

The real-time transient stability assessment (TSA) plays a critical role in the secure operation of the power system. Although the classic numerical integration method, \textit{i.e.} time-domain simulation (TDS), has been widely used in…

Systems and Control · Electrical Eng. & Systems 2022-05-16 Kaixuan Chen , Shunyu Liu , Na Yu , Rong Yan , Quan Zhang , Jie Song , Zunlei Feng , Mingli Song

One of the main challenges of Topological Data Analysis (TDA) is to extract features from persistent diagrams directly usable by machine learning algorithms. Indeed, persistence diagrams are intrinsically (multi-)sets of points in…

Machine Learning · Computer Science 2022-09-27 Raphael Reinauer , Matteo Caorsi , Nicolas Berkouk

A long-standing proposition is that by emulating the operation of the brain's neocortex, a spiking neural network (SNN) can achieve similar desirable features: flexible learning, speed, and efficiency. Temporal neural networks (TNNs) are…

Neural and Evolutionary Computing · Computer Science 2021-02-24 James E. Smith

Many applications collect a large number of time series, for example, the financial data of companies quoted in a stock exchange, the health care data of all patients that visit the emergency room of a hospital, or the temperature sequences…

Information Theory · Computer Science 2017-02-09 Jonathan Mei , José M. F. Moura

Statistical analysis on object data presents many challenges. Basic summaries such as means and variances are difficult to compute. We apply ideas from topology to study object data. We present a framework for using persistence landscapes…

Methodology · Statistics 2019-12-12 Vic Patrangenaru , Peter Bubenik , Robert L. Paige , Daniel Osborne

Topological Data Analysis (TDA) can be used to detect and characterize holes in an image, such as zero-dimensional holes (connected components) or one-dimensional holes (loops). However, there is currently no widely accepted statistical…

Methodology · Statistics 2025-08-26 Susan Glenn , Jessi Cisewski-Kehe , Jun Zhu , William M Bement

Classical topological descriptors used in topological data analysis (TDA) are invariant under permutations of spatial axes and therefore cannot represent the loading direction, which is essential for modeling anisotropic mechanical…

The Mapper algorithm, a technique within topological data analysis (TDA), constructs a simplified graphical representation of high-dimensional data to uncover its underlying shape and structural patterns. The algorithm has attracted…

General Topology · Mathematics 2025-04-15 Vine Nwabuisi Madukpe , Bright Chukwuma Ugoala , Nur Fariha Syaqina Zulkepli

Machining processes are most accurately described using complex dynamical systems that include nonlinearities, time delays, and stochastic effects. Due to the nature of these models as well as the practical challenges which include…

Signal Processing · Electrical Eng. & Systems 2022-01-19 Melih C. Yesilli , Firas A. Khasawneh , Andreas Otto

In this paper we introduce a new data-driven run-time monitoring system for analysing the behaviour of time evolving complex systems. The monitor controls the evolution of the whole system but it is mined from the data produced by its…

Logic in Computer Science · Computer Science 2019-08-12 Matteo Rucco , Luca Tesei , Emanuela Merelli

We introduce a method of time series analysis for two-dimensional transient flow patterns based on Topological Flow Data Analysis (TFDA), a new approach to topological data analysis. TFDA identifies local topological flow structures from an…

Fluid Dynamics · Physics 2026-04-14 Takashi Sakajo , Takeshi Matsumoto , Shizuo Kaji , Tomoo Yokoyama , Tomoki Uda