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Protein structure prediction can be shown to be an NP-hard problem; the number of conformations grows exponentially with the number of residues. The native conformations of proteins occupy a very small subset of these, hence an exploratory,…

Chemical Physics · Physics 2008-02-03 Mehul M. Khimasia , Peter V. Coveney

Genetic Algorithms (GAs) are used to solve search and optimization problems in which an optimal solution can be found using an iterative process with probabilistic and non-deterministic transitions. However, depending on the problem's…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-23 Matheus F. Torquato , Marcelo A. C. Fernandes

In the field of global optimization, many existing algorithms face challenges posed by non-convex target functions and high computational complexity or unavailability of gradient information. These limitations, exacerbated by sensitivity to…

Optimization and Control · Mathematics 2023-10-16 Xinyu Zhang , Sujit Ghosh

Genetic algorithms are a powerful tool in optimization for single and multi-modal functions. This paper provides an overview of their fundamentals with some analytical examples. In addition, we explore how they can be used as a parameter…

One of the main limitations of utilizing optimal wavefront shaping in imaging and authentication applications is the slow speed of the optimization algorithms currently being used. To address this problem we develop a micro-genetic…

Optimization strategies driven by machine learning, such as Bayesian optimization, are being explored across experimental sciences as an efficient alternative to traditional design of experiment. When combined with automated laboratory…

Optimization and Control · Mathematics 2022-10-18 Riley J. Hickman , Matteo Aldeghi , Florian Häse , Alán Aspuru-Guzik

In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Abeer Dyoub , Ivan Letteri

The increasing complexity of fog computing environments calls for efficient resource optimization techniques. In this paper, we propose and evaluate three distributed designs of a genetic algorithm (GA) for resource optimization in fog…

Neural and Evolutionary Computing · Computer Science 2024-06-17 Carlos Guerrero , Isaac Lera , Carlos Juiz

The optimization of dynamic problems is both widespread and difficult. When conducting dynamic optimization, a balance between reinitialization and computational expense has to be found. There are multiple approaches to this. In parallel…

Neural and Evolutionary Computing · Computer Science 2014-01-21 Ronald Hochreiter , Christoph Waldhauser

Purpose: To develop a multi-criteria optimization framework for image guided radiotherapy. Methods: An algorithm is proposed for a multi-criteria framework for the purpose of patient setup verification decision processes. Optimal patient…

Medical Physics · Physics 2011-08-16 Brian Winey , James Balter

The choice of crossover and mutation strategies plays a crucial role in the searchability, convergence efficiency and precision of genetic algorithms. In this paper, a novel improved genetic algorithm is proposed by improving the crossover…

Neural and Evolutionary Computing · Computer Science 2022-10-12 Dingming Yang , Zeyu Yu , Hongqiang Yuan , Yanrong Cui

Motion planning is a key aspect of robotics. A common approach to address motion planning problems is trajectory optimization. Trajectory optimization can represent the high-level behaviors of robots through mathematical formulations.…

Robotics · Computer Science 2024-08-21 Fatemeh Rastgar

Studies have shown that multi-objective optimization problems are hard problems. Such problems either require longer time to converge to an optimum solution, or may not converge at all. Recently some researchers have claimed that real…

Neural and Evolutionary Computing · Computer Science 2014-06-11 Shahab U. Ansari , Sameen Mansha

Several computer vision and artificial intelligence projects are nowadays exploiting the manifold data distribution using, e.g., the diffusion process. This approach has produced dramatic improvements on the final performance thanks to the…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Federico Magliani , Laura Sani , Stefano Cagnoni , Andrea Prati

The talk describes a general approach of a genetic algorithm for multiple objective optimization problems. A particular dominance relation between the individuals of the population is used to define a fitness operator, enabling the genetic…

Artificial Intelligence · Computer Science 2008-09-03 Martin Josef Geiger

Operational decisions in healthcare, logistics, and public policy increasingly involve algorithms that recommend candidate solutions, such as treatment plans, delivery routes, or policy options, while leaving the final choice to human…

Machine Learning · Computer Science 2025-08-06 Michael Lingzhi Li , Shixiang Zhu

Optical focusing through scattering media has important implications for optical applications in medicine, communications, and detection. In recent years, many wavefront shaping methods have been successfully applied to the field, among…

In this study, an interplanetary space flight mission design is established to obtain the minimum \(\Delta V\) required for a rendezvous and sample return mission from an asteroid. Given the initial (observed) conditions of an asteroid, a…

Instrumentation and Methods for Astrophysics · Physics 2015-08-20 Sean Fritz , Kamran Turkoglu

We address the problem of synthetic gene design using Bayesian optimization. The main issue when designing a gene is that the design space is defined in terms of long strings of characters of different lengths, which renders the…

Machine Learning · Statistics 2015-05-08 Javier González , Joseph Longworth , David C. James , Neil D. Lawrence

Radiation Therapy (RT) plays a pivotal role in the treatment of cancer, offering the potential to effectively target and eliminate tumour cells while minimizing harm to surrounding healthy tissues. However, the success of RT heavily depends…

Medical Physics · Physics 2024-02-16 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad
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