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Magnetic Resonance Imaging (MRI) of the fetal brain has become a key tool for studying brain development in vivo. Yet, its assessment remains challenging due to variability in brain maturation, imaging protocols, and uncertain estimates of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Johannes Tischer , Patric Kienast , Marlene Stümpflen , Gregor Kasprian , Georg Langs , Roxane Licandro

Accurate automatic tissue segmentation in fetal brain MRI is a crucial step in clinical diagnosis but remains challenging, particularly due to the dynamically changing anatomy and tissue contrast during fetal development. Existing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-12 Haoan Xu , Tianshu Zheng , Xinyi Xu , Yao Shen , Jiwei Sun , Cong Sun , Guangbin Wang , Zhaopeng Cui , Dan Wu

The automatic segmentation of perinatal brain structures in magnetic resonance imaging (MRI) is of utmost importance for the study of brain growth and related complications. While different methods exist for adult and pediatric MRI data,…

MR images of fetuses allow clinicians to detect brain abnormalities in an early stage of development. The cornerstone of volumetric and morphologic analysis in fetal MRI is segmentation of the fetal brain into different tissue classes.…

Image and Video Processing · Electrical Eng. & Systems 2019-06-12 N. Khalili , N. Lessmann , E. Turk , N. Claessens , R. de Heus , T. Kolk , M. A. Viergever , M. J. N. L. Benders , I. Isgum

Brain segmentation is a fundamental first step in neuroimage analysis. In the case of fetal MRI, it is particularly challenging and important due to the arbitrary orientation of the fetus, organs that surround the fetal head, and…

Automatic segmentation of the fetal brain is still challenging due to the health state of fetal development, motion artifacts, and variability across gestational ages, since existing methods rely on high-quality datasets of healthy fetuses.…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Zhigao Cai , Xing-Ming Zhao

Introduction: Fetal resting-state functional magnetic resonance imaging (rs-fMRI) is a rapidly evolving field that provides valuable insight into brain development before birth. Accurate segmentation of the fetal brain from the surrounding…

Characterizing in-utero brain development is essential for understanding typical and atypical neurodevelopment. Building on prior spatiotemporal fetal brain MRI atlases, we present the CRL-2025 fetal brain atlas, a spatiotemporal (4D) atlas…

Fetal brain magnetic resonance imaging serves as an emerging modality for prenatal counseling and diagnosis in disorders affecting the brain. Machine learning based segmentation plays an important role in the quantification of brain…

Image and Video Processing · Electrical Eng. & Systems 2022-09-21 Marina Fernandez Garcia , Rodrigo Gonzalez Laiz , Hui Ji , Kelly Payette , Andras Jakab

Accurate segmentation of fetal brain magnetic resonance images is crucial for analyzing fetal brain development and detecting potential neurodevelopmental abnormalities. Traditional deep learning-based automatic segmentation, although…

This paper presents FeTal-SAM, a novel adaptation of the Segment Anything Model (SAM) tailored for fetal brain MRI segmentation. Traditional deep learning methods often require large annotated datasets for a fixed set of labels, making them…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Qi Zeng , Weide Liu , Bo Li , Ryne Didier , P. Ellen Grant , Davood Karimi

It is critical to quantitatively analyse the developing human fetal brain in order to fully understand neurodevelopment in both normal fetuses and those with congenital disorders. To facilitate this analysis, automatic multi-tissue fetal…

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

Fetal brain segmentation is an important first step for slice-level motion correction and slice-to-volume reconstruction in fetal MRI. Fast and accurate segmentation of the fetal brain on fetal MRI is required to achieve real-time fetal…

Image and Video Processing · Electrical Eng. & Systems 2022-05-05 Razieh Faghihpirayesh , Davood Karimi , Deniz Erdogmus , Ali Gholipour

Automatic fetal brain tissue segmentation can enhance the quantitative assessment of brain development at this critical stage. Deep learning methods represent the state of the art in medical image segmentation and have also achieved…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Davood Karimi , Caitlin K. Rollins , Clemente Velasco-Annis , Abdelhakim Ouaalam , Ali Gholipour

Fetal brain extraction is a necessary first step in most computational fetal brain MRI pipelines. However, it has been a very challenging task due to non-standard fetal head pose, fetal movements during examination, and vastly heterogeneous…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Razieh Faghihpirayesh , Davood Karimi , Deniz Erdoğmuş , Ali Gholipour

Magnetic resonance imaging of fetal and neonatal brains reveals rapid neurodevelopment marked by substantial anatomical changes unfolding within days. Studying this critical stage of the developing human brain, therefore, requires accurate…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Maik Dannecker , Vasiliki Sideri-Lampretsa , Sophie Starck , Angeline Mihailov , Mathieu Milh , Nadine Girard , Guillaume Auzias , Daniel Rueckert

Deformable templates, or atlases, are images that represent a prototypical anatomy for a population, and are often enhanced with probabilistic anatomical label maps. They are commonly used in medical image analysis for population studies…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Marianne Rakic , Andrew Hoopes , S. Mazdak Abulnaga , Mert R. Sabuncu , John V. Guttag , Adrian V. Dalca

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen
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