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We discuss problems the null hypothesis significance testing (NHST) paradigm poses for replication and more broadly in the biomedical and social sciences as well as how these problems remain unresolved by proposals involving modified…

Methodology · Statistics 2021-07-21 Blakeley B. McShane , David Gal , Andrew Gelman , Christian Robert , Jennifer L. Tackett

The notion of an e-value has been recently proposed as a possible alternative to critical regions and p-values in statistical hypothesis testing. In this paper we consider testing the nonparametric hypothesis of symmetry, introduce…

Statistics Theory · Mathematics 2024-01-29 Vladimir Vovk , Ruodu Wang

Uniformly most powerful tests are statistical hypothesis tests that provide the greatest power against a fixed null hypothesis among all tests of a given size. In this article, the notion of uniformly most powerful tests is extended to the…

Statistics Theory · Mathematics 2014-01-30 Valen E. Johnson

Statistical mechanics relies on the complete though probabilistic description of a system in terms of all the microscopic variables. Its object is to derive therefrom static and dynamic properties involving some reduced set of variables.…

Statistical Mechanics · Physics 2009-10-31 R. Balian

Intuitionistic epistemic logic introduces an epistemic operator, which reflects the intended BHK semantics of intuitionism, to intuitionistic logic. The fundamental assumption concerning intuitionistic knowledge and belief is that it is the…

Logic · Mathematics 2016-01-14 Tudor Protopopescu

Bayes Factors, the Bayesian tool for hypothesis testing, are receiving increasing attention in the literature. Compared to their frequentist rivals ($p$-values or test statistics), Bayes Factors have the conceptual advantage of providing…

Methodology · Statistics 2026-01-21 Stavros Nikolakopoulos , Björn Alfons Edmar , Ioannis Ntzoufras

Sequence matching algorithms such as BLAST and FASTA have been widely used in searching for evolutionary origin and biological functions of newly discovered nucleic acid and protein sequences. As parts of these search tools, alignment…

Biomolecules · Quantitative Biology 2025-10-21 Boryeu Mao

This paper studies whether Bayesian simultaneous three-way hypothesis tests can be logically coherent. Two types of results are obtained. First, under the standard error-wise constant loss, only for a limited set of models can a Bayes…

Statistics Theory · Mathematics 2022-04-05 Bernardo F. Reimann , Rafael Izbicki , Julio M. Stern , Rafael B. Stern , Luis G. Esteves

This introduction to Bayesian statistics presents the main concepts as well as the principal reasons advocated in favour of a Bayesian modelling. We cover the various approaches to prior determination as well as the basis asymptotic…

Methodology · Statistics 2010-02-09 Christian P. Robert , Judith Rousseau

Since its introduction by Fisher, the method of hypothesis testing that relies on computing error probabilities has witnessed several developments. Perhaps the most significant development was the seminal contributions of Neyman and Pearson…

Other Statistics · Statistics 2026-05-08 Reason Machete

The usual procedure for estimating the significance of a peak in a power spectrum is to calculate the probability of obtaining that value or a larger value by chance (known as the "p-value"), on the assumption that the time series contains…

High Energy Astrophysical Phenomena · Physics 2009-11-13 P. A. Sturrock , J. D. Scargle

A storm of favorable or critical publications regarding p-values-based procedures has been observed in both the theoretical and applied literature. We focus on valid definitions of p-values in the scenarios when composite null models are in…

Methodology · Statistics 2020-01-16 Albert Vexler

Testing the (in)equality of variances is an important problem in many statistical applications. We develop default Bayes factor tests to assess the (in)equality of two or more population variances, as well as a test for whether the…

Methodology · Statistics 2022-08-02 Fabian Dablander , Don van den Bergh , Eric-Jan Wagenmakers , Alexander Ly

One can argue that one of the main roles of the subject of statistics is to characterize what the evidence in collected data says about questions of scientific interest. There are two broad questions that we will refer to as the estimation…

Statistics Theory · Mathematics 2024-06-11 Michael Evans

There is a useful counterpart of conformal prediction for e-values, called conformal e-prediction. Conformal prediction can serve as basis for testing the assumption of exchangeability, leading to conformal testing. Similarly, conformal…

Statistics Theory · Mathematics 2024-11-05 Vladimir Vovk , Ilia Nouretdinov , Alex Gammerman

This article proposes an alternative to the Hosmer-Lemeshow (HL) test for evaluating the calibration of probability forecasts for binary events. The approach is based on e-values, a new tool for hypothesis testing. An e-value is a random…

Methodology · Statistics 2023-02-28 Alexander Henzi , Marius Puke , Timo Dimitriadis , Johanna Ziegel

Analysis of credibility is a reverse-Bayes technique that has been proposed by Matthews (2001) to overcome some of the shortcomings of significance tests. A significant result is deemed credible if current knowledge about the effect size is…

Methodology · Statistics 2017-12-11 Leonhard Held

Testing hypotheses is an issue of primary importance in the scientific research, as well as in many other human activities. Much clarification about it can be achieved if the process of learning from data is framed in a stochastic model of…

Data Analysis, Statistics and Probability · Physics 2007-05-23 G. D'Agostini

In Bayesian hypothesis testing, evidence for a statistical model is quantified by the Bayes factor, which represents the relative likelihood of observed data under that model compared to another competing model. In general, computing Bayes…

Computation · Statistics 2021-12-07 Thomas J. Faulkenberry

This work is motivated by learning the individualized minimal clinically important difference, a vital concept to assess clinical importance in various biomedical studies. We formulate the scientific question into a high-dimensional…

Methodology · Statistics 2023-03-28 Huijie Feng , Jingyi Duan , Yang Ning , Jiwei Zhao
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