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Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

We design a low complexity distributed compression scheme for computing arbitrary functions of sources with discrete alphabets. We use a helper-based method that extends the definition of the G{\'a}cs-K{\"o}rner-Witsenhausen (GKW) common…

Information Theory · Computer Science 2021-04-01 Derya Malak

This paper introduces Associative Compression Networks (ACNs), a new framework for variational autoencoding with neural networks. The system differs from existing variational autoencoders (VAEs) in that the prior distribution used to model…

Neural and Evolutionary Computing · Computer Science 2018-04-27 Alex Graves , Jacob Menick , Aaron van den Oord

Delay tomography has so far burdened source and receiver measurement nodes in a network with two requirements such as path establishment and clock synchronization between them. In this letter, we focus on the clock synchronization problem…

Networking and Internet Architecture · Computer Science 2014-02-24 Kensuke Nakanishi , Shinsuke Hara , Takahiro Matsuda , Kenichi Takizawa , Fumie Ono , Ryu Miura

This article seeks to advance coded compressed sensing (CCS) as a practical scheme for unsourced random access. The original CCS algorithm features a concatenated structure where an inner code is tasked with support recovery, and an outer…

Information Theory · Computer Science 2020-10-23 Jamison R. Ebert , Vamsi K. Amalladinne , Jean-Francois Chamberland , Krishna R. Narayanan

Being able to store and transmit human genome sequences is an important part in genomic research and industrial applications. The complete human genome has 3.1 billion base pairs (haploid), and storing the entire genome naively takes about…

Genomics · Quantitative Biology 2020-10-07 Anirduddha Laud , Gaurav Menghani , Madhava Keralapura

This paper studies cross-domain lossy compression through the lens of minimum entropy coupling (MEC) with rate and classification constraints. In this setting, an encoder observes samples from a degraded source domain, while the decoder is…

Information Theory · Computer Science 2026-05-12 Nam Nguyen , Hassan Tavakoli , An Vuong , Thinh Nguyen , Bella Bose

The first step in any genome assembly algorithm entails the conversion from the domain of strings and overlaps to the language of graphs and paths, typically using one of the two conventional methods: de Bruijn graphs or overlap graphs.…

Genomics · Quantitative Biology 2026-04-27 Anton Bankevich

Reducing the cost of sequencing genomes provided by next-generation sequencing technologies has greatly increased the number of genomic projects. As a result, there is a growing need for better assembly and assembly validation methods. One…

Genomics · Quantitative Biology 2022-10-17 Przemysław Stawczyk , Robert Nowak

Noisy shuffling channels capture the main characteristics of DNA storage systems where distinct segments of data are received out of order, after being corrupted by substitution errors. For realistic schemes with short-length segments,…

Information Theory · Computer Science 2024-10-07 Javad Haghighat , Tolga M. Duman

Recently, Generative Adversarial Networks (GANs) have emerged as a popular alternative for modeling complex high dimensional distributions. Most of the existing works implicitly assume that the clean samples from the target distribution are…

Machine Learning · Statistics 2019-02-14 Mohammadreza Soltani , Swayambhoo Jain , Abhinav Sambasivan

As sequencing technologies become more affordable and genomic databases expand continuously, the reuse of publicly available sequencing data emerges as a powerful strategy for studying microbial pathogens. Indeed, raw sequencing reads…

Quantitative Methods · Quantitative Biology 2025-05-16 Damien Richard , Nils Poulicard

This paper investigates data compression that simultaneously allows local decoding and local update. The main result is a universal compression scheme for memoryless sources with the following features. The rate can be made arbitrarily…

Information Theory · Computer Science 2019-10-15 Shashank Vatedka , Aslan Tchamkerten

Regenerating codes provide an efficient way to recover data at failed nodes in distributed storage systems. It has been shown that regenerating codes can be designed to minimize the per-node storage (called MSR) or minimize the…

Information Theory · Computer Science 2014-06-26 Yunghsiang Han , Hung-Ta Pai , Rong Zheng , Pramod K. Varshney

We propose a joint feature compression and transmission scheme for efficient inference at the wireless network edge. Our goal is to enable efficient and reliable inference at the edge server assuming limited computational resources at the…

Information Theory · Computer Science 2020-10-21 Mikolaj Jankowski , Deniz Gunduz , Krystian Mikolajczyk

Deep learning-based lossless compression methods offer substantial advantages in compressing medical volumetric images. Nevertheless, many learning-based algorithms encounter a trade-off between practicality and compression performance.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Qianhao Chen , Jietao Chen

Motivation: Seed location filtering is critical in DNA read mapping, a process where billions of DNA fragments (reads) sampled from a donor are mapped onto a reference genome to identify genomic variants of the donor. State-of-the-art read…

Sequential data is being generated at an unprecedented pace in various forms, including text and genomic data. This creates the need for efficient compression mechanisms to enable better storage, transmission and processing of such data. To…

Computation and Language · Computer Science 2018-11-21 Mohit Goyal , Kedar Tatwawadi , Shubham Chandak , Idoia Ochoa

The task of understanding and interpreting the complex information encoded within genomic sequences remains a grand challenge in biological research and clinical applications. In this context, recent advancements in large language model…

Genomics · Quantitative Biology 2024-09-25 Qihang Zhao , Chi Zhang , Weixiong Zhang

Distributed model training suffers from communication bottlenecks due to frequent model updates transmitted across compute nodes. To alleviate these bottlenecks, practitioners use gradient compression techniques like sparsification,…

Machine Learning · Computer Science 2020-11-02 Saurabh Agarwal , Hongyi Wang , Kangwook Lee , Shivaram Venkataraman , Dimitris Papailiopoulos
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