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Spike sorting refers to the problem of assigning action potentials observed in extra-cellular recordings of neural activity to the neuron(s) from which they originate. We cast this problem as one of learning a convolutional dictionary from…

Methodology · Statistics 2018-06-07 Andrew H. Song , Francisco Flores , Demba Ba

Estimating neuron location from extracellular recordings is essential for developing advanced brain-machine interfaces. Accurate neuron localization improves spike sorting, which involves detecting action potentials and assigning them to…

Neurons and Cognition · Quantitative Biology 2025-08-20 Hao Zhao , Xinhe Zhang , Arnau Marin-Llobet , Xinyi Lin , Jia Liu

Spike sorting is a fundamental preprocessing step for many neuroscience studies which rely on the analysis of spike trains. In this paper, we present two unsupervised spike sorting algorithms based on discriminative subspace learning. The…

Computer Vision and Pattern Recognition · Computer Science 2014-08-25 Mohammad Reza Keshtkaran , Zhi Yang

Extracellular recordings are transient voltage fluctuations in the vicinity of neurons, serving as a fundamental modality in neuroscience for decoding brain activity at single-neuron resolution. Spike sorting, the process of attributing…

Signal Processing · Electrical Eng. & Systems 2026-01-13 Feng Cao , Zishuo Feng , Jicong Zhang , Wei Shi

Spike sorting is essential for extracting neuronal information from neural signals and understanding brain function. With the advent of high-density microelectrode arrays (HDMEAs), the challenges and opportunities in multi-channel spike…

Signal Processing · Electrical Eng. & Systems 2024-12-30 Yuntao Han , Shiwei Wang , Alister Hamilton

Spiking neural networks are the basis of versatile and power-efficient information processing in the brain. Although we currently lack a detailed understanding of how these networks compute, recently developed optimization techniques allow…

Neural and Evolutionary Computing · Computer Science 2021-01-01 Benjamin Cramer , Yannik Stradmann , Johannes Schemmel , Friedemann Zenke

We propose a construction for joint feature learning and clustering of multichannel extracellular electrophysiological data across multiple recording periods for action potential detection and discrimination ("spike sorting"). Our…

The advent of large-scale and high-density extracellular recording devices allows simultaneous recording from thousands of neurons. However, the complexity and size of the data makes it mandatory to develop robust algorithms for fully…

Neurons and Cognition · Quantitative Biology 2019-12-03 Gerrit Hilgen

Despite huge success of artificial intelligence, hardware systems running these algorithms consume orders of magnitude higher energy compared to the human brain, mainly due to heavy data movements between the memory unit and the computation…

Emerging Technologies · Computer Science 2018-10-23 Amogh Agrawal , Aayush Ankit , Kaushik Roy

Spikes are the currency in central nervous systems for information transmission and processing. They are also believed to play an essential role in low-power consumption of the biological systems, whose efficiency attracts increasing…

Neural and Evolutionary Computing · Computer Science 2020-05-05 Qiang Yu , Shenglan Li , Huajin Tang , Longbiao Wang , Jianwu Dang , Kay Chen Tan

Spike-based encoders represent information as sequences of spikes or pulses, which are transmitted between neurons. A prevailing consensus suggests that spike-based approaches demonstrate exceptional capabilities in capturing the temporal…

Signal Processing · Electrical Eng. & Systems 2025-06-03 MHD Anas Alsakkal , Runze Wang , Jayawan Wijekoon , Huajin Tang

Spike-based neuromorphic hardware promises to reduce the energy consumption of image classification and other deep learning applications, particularly on mobile phones or other edge devices. However, direct training of deep spiking neural…

Neural and Evolutionary Computing · Computer Science 2021-01-27 Christoph Stöckl , Wolfgang Maass

There is a need for fast adaptation in spike sorting algorithms to implement brain-machine interface (BMIs) in different applications. Learning and adapting the functionality of the sorting process in real-time can significantly improve the…

Signal Processing · Electrical Eng. & Systems 2025-09-08 Tao Fang , Majid Zamani

Synaptic Sampling Machine (SSM) is a type of neural network model that considers biological unreliability of the synapses. We propose the circuit design of the SSM neural network which is realized through the memristive-CMOS crossbar…

Emerging Technologies · Computer Science 2018-08-03 Irina Dolzhikova , Khaled Salama , Vipin Kizheppatt , Alex Pappachen James

Many previous works in spike sorting study spike classification and compression independently. In this paper, a novel algorithm is proposed called MetaSort to address these two problems. To deal with compression, a novel adaptive level…

Signal Processing · Electrical Eng. & Systems 2026-03-10 Luca M. Meyer , Majid Zamani

The inherent dynamics of the neuron membrane potential in Spiking Neural Networks (SNNs) allows processing of sequential learning tasks, avoiding the complexity of recurrent neural networks. The highly-sparse spike-based computations in…

Hardware Architecture · Computer Science 2021-07-09 Amogh Agrawal , Mustafa Ali , Minsuk Koo , Nitin Rathi , Akhilesh Jaiswal , Kaushik Roy

We study distributed algorithms implemented in a simplified biologically inspired model for stochastic spiking neural networks. We focus on tradeoffs between computation time and network complexity, along with the role of randomness in…

Neural and Evolutionary Computing · Computer Science 2017-08-22 Nancy Lynch , Cameron Musco , Merav Parter

This paper presents a PVT-resilient, subthreshold SRAM-based computing-in-memory (CIM) macro tailored for energy-efficient spiking neural networks (SNNs). The macro integrates in-situ current sensors and distributed voltage regulators to…

Waveform sampling systems are used pervasively in the design of front end electronics for radiation detection. The introduction of new feature extraction algorithms (eg. neural networks) to waveform sampling has the great potential to…

Data Analysis, Statistics and Probability · Physics 2021-09-23 Pengcheng Ai , Zhi Deng , Yi Wang , Linmao Li

Advances in modern technology have enabled the simultaneous recording of neural spiking activity, which statistically can be represented by a multivariate point process. We characterise the second order structure of this process via the…

Methodology · Statistics 2024-04-30 Carla Pinkney , Carolina Euan , Alex Gibberd , Ali Shojaie