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Multi-contrast super-resolution (MCSR) is crucial for enhancing MRI but current deep learning methods are limited. They typically require large, paired low- and high-resolution (LR/HR) training datasets, which are scarce, and are trained…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Yinzhe Wu , Hongyu Rui , Fanwen Wang , Jiahao Huang , Zhenxuan Zhang , Haosen Zhang , Zi Wang , Guang Yang

Early prediction of Mild Cognitive Impairment (MCI) conversion is hampered by a trade-off between immediacy--making fast predictions from a single baseline sMRI--and accuracy--leveraging longitudinal scans to capture disease progression. We…

Machine Learning · Computer Science 2025-06-09 Zhihao Tang , Chaozhuo Li , Litian Zhang , Xi Zhang

Generative models capture the true distribution of data, yielding semantically rich representations. Denoising diffusion models (DDMs) exhibit superior generative capabilities, though efficient representation learning for them are lacking.…

Machine Learning · Computer Science 2025-05-12 Limai Jiang , Yunpeng Cai

In this paper, we contend that a natural objective of representation learning is to compress and transform the distribution of the data, say sets of tokens, towards a low-dimensional Gaussian mixture supported on incoherent subspaces. The…

Machine Learning · Computer Science 2024-09-09 Yaodong Yu , Sam Buchanan , Druv Pai , Tianzhe Chu , Ziyang Wu , Shengbang Tong , Hao Bai , Yuexiang Zhai , Benjamin D. Haeffele , Yi Ma

Magnetic Resonance Imaging (MRI) is a principal diagnostic approach used in the field of radiology to create images of the anatomical and physiological structure of patients. MRI is the prevalent medical imaging practice to find…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Yusuf Brima , Mossadek Hossain Kamal Tushar , Upama Kabir , Tariqul Islam

We present the Score-based Autoencoder for Multiscale Inference (SAMI), a method for unsupervised representation learning that combines the theoretical frameworks of diffusion models and VAEs. By unifying their respective evidence lower…

Machine Learning · Statistics 2025-12-23 Benjamin S. H. Lyo , Eero P. Simoncelli , Cristina Savin

Transformers have demonstrated remarkable performance in natural language processing and computer vision. However, existing vision Transformers struggle to learn from limited medical data and are unable to generalize on diverse medical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Yunhe Gao , Mu Zhou , Di Liu , Zhennan Yan , Shaoting Zhang , Dimitris N. Metaxas

In computer-aided diagnosis (CAD) focused on microscopy, denoising improves the quality of image analysis. In general, the accuracy of this process may depend both on the experience of the microscopist and on the equipment sensitivity and…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Fabio Hernán Gil Zuluaga , Francesco Bardozzo , Jorge Iván Ríos Patiño , Roberto Tagliaferri

Purpose: In the present work we describe the correction of diffusion-weighted MRI for site and scanner biases using a novel method based on invariant representation. Theory and Methods: Pooled imaging data from multiple sources are subject…

Quantitative Methods · Quantitative Biology 2020-02-04 Daniel Moyer , Greg Ver Steeg , Chantal M. W. Tax , Paul M. Thompson

Data is one of the essential ingredients to power deep learning research. Small datasets, especially specific to medical institutes, bring challenges to deep learning training stage. This work aims to develop a practical deep multimodal…

Machine Learning · Computer Science 2019-02-26 Faik Aydin , Maggie Zhang , Michelle Ananda-Rajah , Gholamreza Haffari

We present a rotation-equivariant unsupervised learning framework for the sparse deconvolution of non-negative scalar fields defined on the unit sphere. Spherical signals with multiple peaks naturally arise in Diffusion MRI (dMRI), where…

Image and Video Processing · Electrical Eng. & Systems 2021-02-19 Axel Elaldi , Neel Dey , Heejong Kim , Guido Gerig

Although existing deep learning compressed-sensing-based Magnetic Resonance Imaging (CS-MRI) methods have achieved considerably impressive performance, explainability and generalizability continue to be challenging for such methods since…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Xiaohong Fan , Yin Yang , Ke Chen , Jianping Zhang , Ke Dong

Machine Learning (ML) is increasingly being used for computer aided diagnosis of brain related disorders based on structural magnetic resonance imaging (MRI) data. Most of such work employs biologically and medically meaningful hand-crafted…

Machine Learning · Computer Science 2018-05-04 Ayush Jaiswal , Dong Guo , Cauligi S. Raghavendra , Paul Thompson

As a result of several successful applications in computer vision and image processing, sparse representation (SR) has attracted significant attention in multi-sensor image fusion. Unlike the traditional multiscale transforms (MSTs) that…

Computer Vision and Pattern Recognition · Computer Science 2017-02-14 Qiang Zhang , Yi Liu , Rick S. Blum , Jungong Han , Dacheng Tao

Objective: The computation of anatomical information and laparoscope position is a fundamental block of surgical navigation in Minimally Invasive Surgery (MIS). Recovering a dense 3D structure of surgical scene using visual cues remains a…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Ruofeng Wei , Bin Li , Hangjie Mo , Bo Lu , Yonghao Long , Bohan Yang , Qi Dou , Yunhui Liu , Dong Sun

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent application of deep learning methods for image reconstruction provides a successful data-driven approach to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-22 Ling Chen , Zhishen Huang , Yong Long , Saiprasad Ravishankar

Spatially localized deformation components are very useful for shape analysis and synthesis in 3D geometry processing. Several methods have recently been developed, with an aim to extract intuitive and interpretable deformation components.…

Graphics · Computer Science 2017-12-19 Qingyang Tan , Lin Gao , Yu-Kun Lai , Jie Yang , Shihong Xia

Purpose: Training auto-encoders on simulated signal evolution and inserting the decoder into the forward model improves reconstructions through more compact, Bloch-equation-based representations of signal in comparison to linear subspaces.…

Signal Processing · Electrical Eng. & Systems 2023-05-02 Yamin Arefeen , Junshen Xu , Molin Zhang , Zijing Dong , Fuyixue Wang , Jacob White , Berkin Bilgic , Elfar Adalsteinsson

Registration is a fundamental task in medical robotics and is often a crucial step for many downstream tasks such as motion analysis, intra-operative tracking and image segmentation. Popular registration methods such as ANTs and NiftyReg…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Wentao Zhu , Yufang Huang , Daguang Xu , Zhen Qian , Wei Fan , Xiaohui Xie

Image denoising is a typical ill-posed problem due to complex degradation. Leading methods based on normalizing flows have tried to solve this problem with an invertible transformation instead of a deterministic mapping. However, the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Wenchao Du , Hu Chen , Yi Zhang , H. Yang
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