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A comparative classification scheme provides a good basis for several approaches to understand proteins, including prediction of relations between their structure and biological function. But it remains a challenge to combine a…

Biomolecules · Quantitative Biology 2015-05-20 Shuangwei Hu , Andrei Krokhotin , Antti J. Niemi , Xubiao Peng

We suggest using the method of quantum annealing for computing the ground state of the Heisenberg spin chains. Our initial Hamiltonian describes a spin system in a highly non-uniform magnetic field. The initial Hamiltonian gradually…

Quantum Physics · Physics 2007-05-23 G. P. Berman , V. N. Gorshkov , V. I. Tsifrinovich

The presence of competing interactions due to geometry leads to frustration in quantum spin models. As a consequence, the ground state of such systems often displays a large degeneracy that can be lifted due to thermal or quantum effects.…

Statistical Mechanics · Physics 2024-08-23 Pratyankara Narasimhan , Stephan Humeniuk , Ananda Roy , Victor Drouin-Touchette

With the current progress of quantum computing, quantum annealing is being introduced as a powerful method to solve hard computational problems. In this paper, we study the potential capability of quantum annealing in solving the phase…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Mohammad Kashfi Haghighi , Nikitas Dimopoulos

Lattices are very important objects in the effort to construct cryptographic primitives that are secure against quantum attacks. A central problem in the study of lattices is that of finding the shortest non-zero vector in the lattice.…

Quantum Physics · Physics 2022-09-05 Nishant Rodrigues , Brad Lackey

I present a novel use of quantum annealing to solve the Set Splitting Problem using (QUBO) problem formulation. The contribution of the work is in formulating penalty functions that ensure the ground state of the QUBO Hamiltonian…

Quantum Physics · Physics 2025-08-11 Sean Borneman

Recent work has shown that quantum annealing for machine learning, referred to as QAML, can perform comparably to state-of-the-art machine learning methods with a specific application to Higgs boson classification. We propose QAML-Z, a…

Quantum Physics · Physics 2021-01-04 Alexander Zlokapa , Alex Mott , Joshua Job , Jean-Roch Vlimant , Daniel Lidar , Maria Spiropulu

An efficient scheme to compute the geometric entanglement per lattice site for quantum many-body systems on a periodic finite-size chain is proposed in the context of a tensor network algorithm based on the matrix product state…

Statistical Mechanics · Physics 2015-05-28 Bing-Quan Hu , Xi-Jing Liu , Jin-Hua Liu , Huan-Qiang Zhou

Quantum annealing is a generic algorithm using quantum-mechanical fluctuations to search for the solution of an optimization problem. The present paper first reviews the fundamentals of quantum annealing and then reports on preliminary…

Disordered Systems and Neural Networks · Physics 2010-06-10 Masayuki Ohzeki , Hidetoshi Nishimori

We explore the potential application of quantum computers to the examination of lattice holography, which extends to the strongly-coupled bulk theory regime. With adiabatic evolution, we compute the ground state of a spin system on a…

High Energy Physics - Lattice · Physics 2023-12-19 Ying-Ying Li , Muhammad Omer Sajid , Judah Unmuth-Yockey

While quantum computing proposes promising solutions to computational problems not accessible with classical approaches, due to current hardware constraints, most quantum algorithms are not yet capable of computing systems of practical…

Optimal parameter setting for applications problems embedded into hardware graphs is key to practical quantum annealers (QA). Embedding chains typically crop up as harmful Griffiths phases, but can be used as a resource as we show here: to…

Quantum Physics · Physics 2021-01-04 Sergey Knysh , Eugeniu Plamadeala , Davide Venturelli

Quantum annealing is an innovative idea and method for avoiding the increase of the calculation cost of the combinatorial optimization problem. Since the combinatorial optimization problems are ubiquitous, quantum annealing machine with…

Statistical Mechanics · Physics 2020-01-13 Shohei Watabe , Yuya Seki , Shiro Kawabata

We present a classical algorithm to find approximate solutions to instances of quadratic unconstrained binary optimisation. The algorithm can be seen as an analogue of quantum annealing under the restriction of a product state space, where…

Quantum Physics · Physics 2023-02-14 Joseph Bowles , Alexandre Dauphin , Patrick Huembeli , José Martinez , Antonio Acín

Quantum annealing targets low-energy solutions of Ising/QUBO problems, but reliable assessment requires more than best-energy comparisons. This dissertation develops a benchmarking framework for D-Wave quantum annealers that combines strong…

Quantum Physics · Physics 2026-05-01 Tomasz Śmierzchalski

Among the unsolved problems in computational biology, protein folding is one of the most interesting challenges. To study this folding, tools like neural networks and genetic algorithms have received a lot of attention, mainly due to the…

Biomolecules · Quantitative Biology 2016-08-23 Jacques M. Bahi , Nathalie Côté , Christophe Guyeux , Michel Salomon

A novel quantum-classical hybrid scheme is proposed to efficiently solve large-scale combinatorial optimization problems. The key concept is to introduce a Hamiltonian dynamics of the classical flux variables associated with the quantum…

Quantum Physics · Physics 2021-04-28 Hirotaka Irie , Haozhao Liang , Takumi Doi , Shinya Gongyo , Tetsuo Hatsuda

We solve a model that has basic features that are desired for quantum annealing computations: entanglement in the ground state, controllable annealing speed, ground state energy separated by a gap during the whole evolution, and a…

Quantum Physics · Physics 2018-11-14 Fuxiang Li , V. Y. Chernyak , N. A. Sinitsyn

In the standard approach to lattice proteins the models based on nearest neighbor interaction are used. In this kind of models it is difficult to explain the existence of secondary structures --- special preferred conformations of protein…

Soft Condensed Matter · Physics 2013-12-17 S. V. Kozyrev , I. V. Volovich

A reduced protein model with five to six atoms per amino acid and five amino acid types is developed and tested on a three-helix-bundle protein, a 46-amino acid fragment from staphylococcal protein A. The model does not rely on the widely…

Soft Condensed Matter · Physics 2007-05-23 Giorgio Favrin , Anders Irbäck , Stefan Wallin
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