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This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

We present a novel framework based on optimal transport for the challenging problem of comparing graphs. Specifically, we exploit the probabilistic distribution of smooth graph signals defined with respect to the graph topology. This allows…

Machine Learning · Computer Science 2019-12-09 Hermina Petric Maretic , Mireille EL Gheche , Giovanni Chierchia , Pascal Frossard

Guided image filter is a well-known local filter in image processing. However, the presence of halo artifacts is a common issue associated with this type of filter. This paper proposes an algorithm that utilizes gradient information to…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Bo Wang , Yihong Wang , Xiubao Sui , Yuan Liu , Qian Chen

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Uncertainty in medical image segmentation is inherently non-uniform, with boundary regions exhibiting substantially higher ambiguity than interior areas. Conventional training treats all pixels equally, leading to unstable optimization…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Jinming Zhang , Youpeng Yang , Xi Yang , Haosen Shi , Yuyao Yan , Qiufeng Wang , Guangliang Cheng , Kaizhu Huang

Problems in differentiable rendering often involve optimizing scene parameters that cause motion in image space. The gradients for such parameters tend to be sparse, leading to poor convergence. While existing methods address this sparsity…

Graphics · Computer Science 2025-03-31 Ishit Mehta , Manmohan Chandraker , Ravi Ramamoorthi

Optimal transport and Wasserstein distance are prominent tools to quantify the space of probability distributions. From a novel viewpoint of manifold hypothesis in machine learning being a possible guide for the holographic principle, we…

High Energy Physics - Theory · Physics 2026-04-21 Koji Hashimoto , Norihiro Tanahashi

Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Talha Qaiser , Yee-Wah Tsang , Daiki Taniyama , Naoya Sakamoto , Kazuaki Nakane , David Epstein , Nasir Rajpoot

Illumination estimation remains a pivotal challenge in image processing, particularly for robotics, where robust environmental perception is essential under varying lighting conditions. Traditional approaches, such as RGB histograms and…

Image and Video Processing · Electrical Eng. & Systems 2025-07-04 Selcuk Yazar

This paper presents a new method to extract image low-level features, namely mix histogram (MH), for content-based image retrieval. Since color and edge orientation features are important visual information which help the human visual…

Computer Vision and Pattern Recognition · Computer Science 2019-09-24 Mohammad Rezaei , Ali Ahmadi , Navid Naderi

This paper introduces a new nonlinear dictionary learning method for histograms in the probability simplex. The method leverages optimal transport theory, in the sense that our aim is to reconstruct histograms using so-called displacement…

This work establishes a framework for solving inverse boundary problems with the geodesic based quadratic Wasserstein distance ($W_{2}$). A general form of the Fr\'echet gradient is systematically derived by optimal transportation (OT)…

Numerical Analysis · Mathematics 2022-10-31 Gang Bao , Yixuan Zhang

In anti-cancer drug development, a major scientific challenge is disentangling the complex relationships between high-dimensional genomics data from patient tumor samples, the corresponding tumor's organ of origin, the drug targets…

Machine Learning · Computer Science 2024-03-29 Omid Bazgir , Zichen Wang , Ji Won Park , Marc Hafner , James Lu

Segmentation of nuclei regions from histological images enables morphometric analysis of nuclei structures, which in turn helps in the detection and diagnosis of diseases under consideration. To develop a nuclei segmentation algorithm,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Suman Mahapatra , Pradipta Maji

Estimating the orientations of nodes in a pose graph from relative angular measurements is challenging because the variables live on a manifold product with nontrivial topology and the maximum-likelihood objective function is non-convex and…

Robotics · Computer Science 2012-11-14 Luca Carlone , Andrea Censi

Shape matching has been a long-studied problem for the computer graphics and vision community. The objective is to predict a dense correspondence between meshes that have a certain degree of deformation. Existing methods either consider the…

Computer Vision and Pattern Recognition · Computer Science 2022-02-04 Mahdi Saleh , Shun-Cheng Wu , Luca Cosmo , Nassir Navab , Benjamin Busam , Federico Tombari

The popular use of histopathology images, such as hematoxylin and eosin (H&E), has proven to be useful in detecting tumors. However, moving such cancer cases forward for treatment requires accurate on the amount of the human epidermal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Olaide N. Oyelade , Oliver Hoxey , Yulia Humrye

Cross-domain alignment between two sets of entities (e.g., objects in an image, words in a sentence) is fundamental to both computer vision and natural language processing. Existing methods mainly focus on designing advanced attention…

Computation and Language · Computer Science 2020-07-28 Liqun Chen , Zhe Gan , Yu Cheng , Linjie Li , Lawrence Carin , Jingjing Liu

Brain pathologies often manifest as partial or complete loss of tissue. The goal of many neuroimaging studies is to capture the location and amount of tissue changes with respect to a clinical variable of interest, such as disease…

Computer Vision and Pattern Recognition · Computer Science 2022-08-12 Samuel Gerber , Marc Niethammer , Ebrahim Ebrahim , Joseph Piven , Stephen R. Dager , Martin Styner , Stephen Aylward , Andinet Enquobahrie

Lung nodules are commonly detected in screening for patients with a risk for lung cancer. Though the status of large nodules can be easily diagnosed by fine needle biopsy or bronchoscopy, small nodules are often difficult to classify on…

Quantitative Methods · Quantitative Biology 2018-07-03 Min Zhang , Qianli Ma , Chengfeng Wen , Hai Chen , Deruo Liu , Xianfeng Gu , Jie He , Xiaoyin Xu
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