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Autism Spectrum Disorder (ASD) is a neurodevelopmental condition that encompasses a wide variety of symptoms and degrees of impairment, which makes the diagnosis and treatment challenging. Functional magnetic resonance imaging (fMRI) has…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Yinchi Zhou , Peiyu Duan , Yuexi Du , Nicha C. Dvornek

One major impediment to the wider use of deep learning for clinical decision making is the difficulty of assigning a level of confidence to model predictions. Currently, deep Bayesian neural networks and sparse Gaussian processes are the…

Graph neural networks (GNNs) have demonstrated success in learning representations of brain graphs derived from functional magnetic resonance imaging (fMRI) data. However, existing GNN methods assume brain graphs are static over time and…

Machine Learning · Computer Science 2023-07-11 Alexander Campbell , Antonio Giuliano Zippo , Luca Passamonti , Nicola Toschi , Pietro Lio

Brain Functional Networks (BFNs), graph theoretical models of brain activity data, provide a systems perspective of complex functional connectivity within the brain. Neurological disorders are known to have basis in abnormal functional…

Quantitative Methods · Quantitative Biology 2016-08-30 Megha Singh , Rahul Badhwar , Ganesh Bagler

Growing evidence from recent studies implies that microRNA or miRNA could serve as biomarkers in various complex human diseases. Since wet-lab experiments are expensive and time-consuming, computational techniques for miRNA-disease…

Quantitative Methods · Quantitative Biology 2021-11-30 Thi Ngan Dong , Megha Khosla

An optimal individualized treatment rule (ITR) is a function that takes a patient's characteristics, such as demographics, biomarkers, and treatment history, and outputs a treatment that is expected to give the best outcome for that…

Methodology · Statistics 2026-02-05 Augustine Wigle , Erica E. M. Moodie

We explore the issue of refining an existent Bayesian network structure using new data which might mention only a subset of the variables. Most previous works have only considered the refinement of the network's conditional probability…

Artificial Intelligence · Computer Science 2013-02-28 Wai Lam , Fahiem Bacchus

Analysis of brain imaging scans is critical to understanding the way the human brain functions, which can be leveraged to treat injuries and conditions that affect the quality of life for a significant portion of the human population. In…

Methodology · Statistics 2022-03-02 Daniel Spencer , David Bolin , Mary Beth Nebel , Amanda Mejia

Predicated on the increasing abundance of electronic health records, we investi- gate the problem of inferring individualized treatment effects using observational data. Stemming from the potential outcomes model, we propose a novel multi-…

Machine Learning · Computer Science 2017-05-30 Ahmed M. Alaa , Mihaela van der Schaar

Noises, artifacts, and loss of information caused by the magnetic resonance (MR) reconstruction may compromise the final performance of the downstream applications. In this paper, we develop a re-weighted multi-task deep learning method to…

Computer Vision and Pattern Recognition · Computer Science 2020-11-30 Kehan Qi , Yu Gong , Xinfeng Liu , Xin Liu , Hairong Zheng , Shanshan Wang

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

Machine Learning · Computer Science 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Insomnia affects a vast population of the world and can have a wide range of causes. Existing treatments for insomnia have been linked with many side effects like headaches, dizziness, etc. As such, there is a clear need for improved…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Kevin Monteiro , Sam Nallaperuma-Herzberg , Martina Mason , Steve Niederer

The article considers semi-supervised multitask learning on a Gaussian mixture model (GMM). Using methods from statistical physics, we compute the asymptotic Bayes risk of each task in the regime of large datasets in high dimension, from…

Machine Learning · Statistics 2023-03-06 Minh-Toan Nguyen , Romain Couillet

Emerging evidence showed that major depressive disorder (MDD) is associated with disruptions of brain structural and functional networks, rather than impairment of isolated brain region. Thus, connectome-based models capable of predicting…

Neurons and Cognition · Quantitative Biology 2021-10-18 Aya Kabbara , Gabriel Robert , Mohamad Khalil , Marc Verin , Pascal Benquet , Mahmoud Hassan

Cognitive task classification using machine learning plays a central role in decoding brain states from neuroimaging data. By integrating machine learning with brain network analysis, complex connectivity patterns can be extracted from…

Machine Learning · Computer Science 2026-01-01 Debasis Maji , Arghya Banerjee , Debaditya Barman

Accurate quantification of uncertainty in neural network predictions remains a central challenge for scientific applications involving high-dimensional, correlated data. While existing methods capture either aleatoric or epistemic…

Machine Learning · Computer Science 2025-08-26 Harrison J. Goldwyn , Mitchell Krock , Johann Rudi , Daniel Getter , Julie Bessac

Alzheimer's disease (AD) is the most common age-related dementia. It remains a challenge to identify the individuals at risk of dementia for precise management. Brain MRI offers a noninvasive biomarker to detect brain aging. Previous…

Machine Learning · Computer Science 2021-07-26 Chao Li , Yiran Wei , Xi Chen , Carola-Bibiane Schonlieb

We consider the problem of learning Bayesian network classifiers that maximize the marginover a set of classification variables. We find that this problem is harder for Bayesian networks than for undirected graphical models like maximum…

Machine Learning · Computer Science 2012-07-09 Yuhong Guo , Dana Wilkinson , Dale Schuurmans

Deep neural networks (DNNs) have made a revolution in numerous fields during the last decade. However, in tasks with high safety requirements, such as medical or autonomous driving applications, providing an assessment of the models…

Machine Learning · Computer Science 2020-11-20 Omer Achrack , Raizy Kellerman , Ouriel Barzilay

Magnetotelluric (MT) inversion is a key technique in geophysics for imaging deep subsurface resistivity structures. However, the inherent ill-posedness and non-uniqueness of inverse problems make them challenging to solve. While supervised…

Geophysics · Physics 2025-08-06 Dhruv Poddar , Rohan Sharma , Divakar Vashisth
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