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Related papers: Principal Amalgamation Analysis for Microbiome Dat…

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Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the cellular level. By providing data on gene expression for each individual cell, scRNA-seq generates large datasets with thousands of…

Computational Complexity · Computer Science 2025-02-11 Md Romizul Islam , Swakkhar Shatabda

Principal component analysis (PCA) is arguably the most widely used approach for large-dimensional factor analysis. While it is effective when the factors are sufficiently strong, it can be inconsistent when the factors are weak and/or the…

Methodology · Statistics 2025-08-22 Zhongyuan Lyu , Ming Yuan

Photoacoustic imaging (PAI) is a promising emerging imaging modality that enables spatially resolved imaging of optical tissue properties up to several centimeters deep in tissue, creating the potential for numerous exciting clinical…

Medical Physics · Physics 2021-04-15 Janek Gröhl , Melanie Schellenberg , Kris Dreher , Lena Maier-Hein

Motivated by regression analysis for microbiome compositional data, this paper considers generalized linear regression analysis with compositional covariates, where a group of linear constraints on regression coefficients are imposed to…

Methodology · Statistics 2018-01-11 Jiarui Lu , Pixu Shi , Hongzhe Li

There is growing interest in using the close connection between differential geometry and statistics to model smooth manifold-valued data. In particular, much work has been done recently to generalize principal component analysis (PCA), the…

Other Statistics · Statistics 2016-10-07 Drew Lazar , Lizhen Lin

Principal component analysis (PCA) represents a standard approach to identify collective variables $\{x_i\}\!=\!\boldsymbol{x}$, which can be used to construct the free energy landscape $\Delta G(\boldsymbol{x})$ of a molecular system.…

Biomolecules · Quantitative Biology 2019-05-30 Matthias Post , Steffen Wolf , Gerhard Stock

"Deep Archetypal Analysis" generates latent representations of high-dimensional datasets in terms of fractions of intuitively understandable basic entities called archetypes. The proposed method is an extension of linear "Archetypal…

Machine Learning · Computer Science 2020-01-27 Sebastian Mathias Keller , Maxim Samarin , Mario Wieser , Volker Roth

Sparse Principal Component Analysis (sPCA) is a cardinal technique for obtaining combinations of features, or principal components (PCs), that explain the variance of high-dimensional datasets in an interpretable manner. This involves…

Optimization and Control · Mathematics 2025-12-02 Ryan Cory-Wright , Jean Pauphilet

Principal component analysis (PCA) is a statistical technique commonly used in multivariate data analysis. However, PCA can be difficult to interpret and explain since the principal components (PCs) are linear combinations of the original…

Mathematical Software · Computer Science 2013-12-24 W. Liu , H. Zhang , D. Tao , Y. Wang , K. Lu

The human microbiome is a complex ecological system, and describing its structure and function under different environmental conditions is important from both basic scientific and medical perspectives. Viewed through a biostatistical lens,…

Applications · Statistics 2017-11-17 Kris Sankaran , Susan P. Holmes

Compositional data have two unique characteristics compared to typical multivariate data: the observed values are nonnegative and their summand is exactly one. To reflect these characteristics, a specific regularized regression model with…

Machine Learning · Computer Science 2018-12-24 Jong-June Jeon , Yongdai Kim , Sungho Won , Hosik Choi

With the advance of modern technology, more and more data are being recorded continuously during a time interval or intermittently at several discrete time points. They are both examples of "functional data", which have become a prevailing…

Methodology · Statistics 2015-07-21 Jane-Ling Wang , Jeng-Min Chiou , Hans-Georg Mueller

Methods for supervised principal component analysis (SPCA) aim to incorporate label information into principal component analysis (PCA), so that the extracted features are more useful for a prediction task of interest. Prior work on SPCA…

Machine Learning · Statistics 2022-08-18 Alexander Ritchie , Laura Balzano , Daniel Kessler , Chandra S. Sripada , Clayton Scott

Photoacoustic imaging (PAI) is an emerging biomedical imaging modality capable of providing both high contrast and high resolution of optical and UltraSound (US) imaging. When a short duration laser pulse illuminates the tissue as a target…

Signal Processing · Electrical Eng. & Systems 2018-01-19 Moein Mozaffarzadeh , Ali Mahloojifar , Mahdi Orooji

A major challenge in nuclear fusion research is the coherent combination of data from heterogeneous diagnostics and modelling codes for machine control and safety as well as physics studies. Measured data from different diagnostics often…

Dimensional analysis (DA) pays attention to fundamental physical dimensions such as length and mass when modelling scientific and engineering systems. It goes back at least a century to Buckingham's Pi theorem, which characterizes a…

Machine Learning · Computer Science 2023-12-19 G. Alexi Rodriguez-Arelis , William J. Welch

Sparse PCA provides a linear combination of small number of features that maximizes variance across data. Although Sparse PCA has apparent advantages compared to PCA, such as better interpretability, it is generally thought to be…

Machine Learning · Statistics 2012-10-29 Youwei Zhang , Laurent El Ghaoui

Principal Component Analysis (PCA) is a pivotal technique widely utilized in the realms of machine learning and data analysis. It aims to reduce the dimensionality of a dataset while minimizing the loss of information. In recent years,…

Cryptography and Security · Computer Science 2024-02-06 Xirong Ma

We extend the principal component analysis (PCA) to second-order stationary vector time series in the sense that we seek for a contemporaneous linear transformation for a $p$-variate time series such that the transformed series is segmented…

Methodology · Statistics 2018-12-21 Jinyuan Chang , Bin Guo , Qiwei Yao

This paper proposes an innovative extension of Principal Component Analysis (PCA) that transcends the traditional assumption of data lying in Euclidean space, enabling its application to data on Riemannian manifolds. The primary challenge…

Machine Learning · Statistics 2025-06-03 Oldemar Rodríguez
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