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Light sheet fluorescence microscopy (LSFM) has transformed the way we visualize biological tissues in three dimensions, offering high-resolution imaging while minimizing photo-induced damage to the samples. Recent breakthroughs in…
Flexible graphite (FG) with 1 - 1.2 g/cm$^3$ density is employed as beam energy absorber material in the CERN's Large Hadron Collider (LHC) beam dumping system. However, the increase of energy deposited expected for new HL-LHC…
A rapid and efficient photo-bleaching process was demonstrated with a high-energy nanosecond pulse to recover existing and/or revealed color centers on 10 kGy Gamma-irradiated Yb-doped optical fiber. Multi-mJ pulsed laser based on an…
Low-light optical imaging refers to the use of cameras to capture images with minimal photon flux. This area has broad application to diverse fields, including optical microscopy for biological studies. In such studies, it is important to…
Strong Fermi level pinning (FLP) - often attributed to metal-induced gap states at the interfacial contacts - severely reduces the tunability of the Schottky barrier height of the junction and limits applications of the 2D materials in…
The notion of lasing with biologics has recently been realized and has since rapidly developed with the collective objective of creating lasers $\textit{in vivo}$. One limitation of achieving this goal is the requirement of exogenous laser…
Lasers based on biological materials are attracting an increasing interest in view of their use in integrated and transient photonics. DNA as optical biopolymer in combination with highly-emissive dyes has been reported to have excellent…
We investigate the dynamics of the cavitation bubble induced by 2.9 {\mu}m mid-IR laser pulses (10 ns, 10-50 {\mu}J) resulting in a plasma-free direct fast heating of water due to a strong vibrational absorption. We establish a direct…
Whispering-gallery mode (WGM) resonators combine small optical mode volumes with narrow resonance linewidths, making them exciting platforms for a variety of applications. Here we report a flying WGM microlaser, realized by optically…
Astrophysical observations suggest the existence of an unknown kind of matter in the Universe, in the frame of the $\Lambda$CDM model. The research field of dark matter covers an energy scale going from massive objects to ultra-light scalar…
Cryogenic ultra-stable lasers have extremely low thermal noise limits and frequency drifts, but they are more seriously affected by vibration noise from cryostats. Main material candidates for cryogenic ultra-stable cavities include silicon…
Random lasers use radiative gain and multiple scatterers in disordered media to generate light amplification. In this study, we demonstrate a random laser based on diamond nanoneedles that act as scatterers in combination with fluorescent…
Photonic integration offers the potential to bring complex high-performance optical systems to the form factor of a compact semiconductor chip. However, the range of system functions accessible critically depends on the extent to which…
We demonstrate the fabrication of defect-free optical-nanofiber photonic-crystal Fabry-Perot resonators with quality factors exceeding 10^7 using single-shot femtosecond laser ablation. An investigation of the nonlinear optical properties…
Fluorescence imaging is the most widely used method for unveiling the molecular composition of biological specimens. However, the weak optical emission of fluorescent probes and the tradeoff between imaging speed and sensitivity is…
Ultrashort (femtosecond, fs) laser pulses have fascinating properties as they allow to confine optical energy on extreme scales in space and time. Such fs-laser pulsed beams can be seen as spatially thin slices of intense light that are…
Concentration quenching is a well-known challenge in many fluorescence imaging applications. Here we show that the optical emission from hundreds of chromophores confined onto the surface of a virus particle 28 nm diameter can be recovered…
A femtosecond frequency-doubled Erbium-doped fiber laser with adjustable pulse repetition rate is developed and applied in two-photon excited fluorescence microscopy. The all-fiber laser system provides the fundamental pulse at 1560 nm…
Absolute quantification of biological samples entails determining expression levels in precise numerical copies, offering enhanced accuracy and superior performance for rare templates. However, existing methodologies suffer from significant…
The mechanical properties of biological fluids can serve as early indicators of disease, offering valuable insights into complex physiological and pathological processes. However, the existing technologies can hardly support high throughput…