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Related papers: An mCherry biolaser based on microbubble cavity wi…

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Biological lasers have attracted vast attention because of their potential medical application prospects, especially the low threshold biological laser, which can be used for ultrasensitive biological detection while ensuring that its…

Optics · Physics 2022-06-29 Shuoying Zhao , Gaoshang Li , Xubiao Peng , Jiyang Ma , Zhangqi Yin , Qing Zhao

Microsphere solid-state biolasers made of biomaterials-bovine serum albumin, pectin and cellulose are demonstrated. The fabrication is simple, based on emulsion, and with green processing. A lasing threshold of 1 microJ/mm2 and Q factor of…

Biolasers made of biological materials have attracted a great of research attention due to their biocompatibility and biodegradability, which have the potential for biosensors and biointegration. However, the current fabrication method of…

In this study, we explore the electron transition mechanism and optical properties of the popular red fluorescent protein mCherry. By examining the charge transfer spectrum and combining it with the mCherry hole-electron distribution, we…

Chemical Physics · Physics 2023-04-24 Yuanjin Wang , Gaoshang Li , Jin Dai , Xubiao Peng , Qing Zhao

Decades ago, the losses of glasses in the near infrared (near-IR) were investigated in views of developments for optical telecommunications. Today, properties in the mid-infrared (mid-IR) are of interest for molecular spectroscopy…

Optics · Physics 2016-12-07 C. Lecaplain , C. Javerzac-Galy , M. L. Gorodetsky , T. J. Kippenberg

A single-biomolecule optical toggle-switch is demonstrated based on a mutated green fluorescent protein (GFP). We have exploited molecular biology techniques to tailor GFP molecular structure and photophysical properties and give it…

Mid-infrared photothermal microscopy is a new chemical imaging technology in which a visible beam senses the photothermal effect induced by a pulsed infrared laser. This technology provides infrared spectroscopic information at sub-micron…

Optics · Physics 2021-04-08 Yi Zhang , Haonan Zong , Cheng Zong , Yuying Tan , Meng Zhang , Yuewei Zhan , Ji-Xin Cheng

Biosensors are an essential tool for medical diagnostics, environmental monitoring and food safety. Typically, biosensors are designed to detect specific analytes through functionalization with the appropriate capture agents. However, the…

Medical Physics · Physics 2023-09-26 Simon J. Ward , Tengfei Cao , Xiang Zhou , Catie Chang , Sharon M. Weiss

The advantages of high-quality-factor whispering gallery mode microresonators can be applied to develop novel photonic devices for the mid-IR range. ZBLAN (glass based on heavy metal fluorides) is one of the most promising materials to be…

Nano- and microparticles are popular media to enhance optical signals, including fluorescence from a dye proximal to the particle. Here we show that homogeneous, lossless, all-dielectric spheres with diameters in the mesoscale range,…

Laser sensing has a wide range of applications. In this paper, we propose a pH sensing laser with an ultra-low threshold and low sample consumption based on a whispering-gallery-mode microbubble resonator. Rhodamine 6G aqueous solutions…

Optics · Physics 2023-12-07 Yue Cao , Jin Dai , Xubiao Peng , Jiyang Ma , Qing Zhao

The fast component of the barium fluoride (BaF$_{2}$) crystal luminescence with the emission peak at 220 nm allows those crystals to be employed in fast calorimeters operating in harsh radiation environment. However, the slow component with…

Biomarker detection is the key to identifying health risks. However, designing sensitive biosensors in a single-use mode for disease diagnosis remains a major challenge. Here, we report sub-monolayer biolasers with remarkable repeatability…

Sensing biological forces with microscopic lasers is an emerging technique that offers significant advantages over conventional fluorescent probes and imaging-based techniques. However, the limited availability of suitable deformable or…

Optics · Physics 2026-04-13 Melisa A. Bayrak , David Ripp , Joseph S. Hill , Marcel Schubert

Semiconductor lasers with ultra-low thresholds and minimal footprints are a topic of active research. Such devices require a combination of high quality factor laser cavities with small active region volumes, which drives the quest for…

Multiphoton microscopes employ femtosecond lasers as light sources because the high peak power of the ultrashort pulse allows for multiphoton excitation of fluorescence in the examined sample. However, such short pulses are susceptible to…

Optics · Physics 2024-08-13 Katarzyna Kunio , Jakub Bogusławski , Grzegorz Soboń

We present evidence of ultrafast random lasing from the fluorescent protein DsRed2 embedded in a random one-dimensional cavity. Lasing is achieved when a purified protein solution, placed inside a layered random medium, is optically excited…

Optics · Physics 2015-02-16 T. M. Drane , H. Bach , M. Shapiro , V. Milner

Barium magnesium fluoride (BMF) is a ferroelectric crystal with a transparency range far beyond the one of other optical materials. In particular, its low loss in the deep ultraviolet makes this material an unique candidate for frequency…

Plasmonic lasers provide a paradigm-changing approach for the generation of coherent light at the nanoscale. In addition to the usual properties of coherent radiation, the emission of plasmonic lasers can feature high sensitivity to the…

Compact, low-noise coherent light sources in the visible remain challenging due to limited gain platforms and inefficient pumping. We report a new route to visible microlasing based on direct, one-photon blue pumping and an amorphous…

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