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Advancements in digital imaging technologies have sparked increased interest in using multiplexed immunofluorescence (mIF) images to visualise and identify the interactions between specific immunophenotypes with the tumour microenvironment…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Piumi Sandarenu , Julia Chen , Iveta Slapetova , Lois Browne , Peter H. Graham , Alexander Swarbrick , Ewan K. A. Millar , Yang Song , Erik Meijering

The performance of existing supervised neuron segmentation methods is highly dependent on the number of accurate annotations, especially when applied to large scale electron microscopy (EM) data. By extracting semantic information from…

Computer Vision and Pattern Recognition · Computer Science 2023-10-09 Yinda Chen , Wei Huang , Shenglong Zhou , Qi Chen , Zhiwei Xiong

Training a deep learning model to classify histopathological images is challenging, because of the color and shape variability of the cells and tissues, and the reduced amount of available data, which does not allow proper learning of those…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Saypraseuth Mounsaveng , Issam Laradji , David Vázquez , Marco Perdersoli , Ismail Ben Ayed

Deep neural networks are capable of learning powerful representations to tackle complex vision tasks but expose undesirable properties like the over-fitting issue. To this end, regularization techniques like image augmentation are necessary…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Haohang Xu , Shuangrui Ding , Manqi Zhao , Dongsheng Jiang

Self-supervised learning excels in learning representations from large amounts of unlabeled data, demonstrating success across multiple data modalities. Yet, extending self-supervised learning to new modalities is non-trivial because the…

Machine Learning · Computer Science 2024-02-23 Johnathan Xie , Yoonho Lee , Annie S. Chen , Chelsea Finn

Live-cell imaging of multiple subcellular structures is essential for understanding subcellular dynamics. However, the conventional multi-color sequential fluorescence microscopy suffers from significant imaging delays and limited number of…

Subcellular Processes · Quantitative Biology 2025-01-13 Mingyang Chen , Luhong Jin , Xuwei Xuan , Defu Yang , Yun Cheng , Ju Zhang

Unsupervised anomaly detection has gained significant attention in the field of medical imaging due to its capability of relieving the costly pixel-level annotation. To achieve this, modern approaches usually utilize generative models to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Rui Xu , Yunke Wang , Bo Du

Self-supervised learning methods based on image patch reconstruction have witnessed great success in training auto-encoders, whose pre-trained weights can be transferred to fine-tune other downstream tasks of image understanding. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Junjia Huang , Haofeng Li , Guanbin Li , Xiang Wan

The task of medical image segmentation presents unique challenges, necessitating both localized and holistic semantic understanding to accurately delineate areas of interest, such as critical tissues or aberrant features. This complexity is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Pranav Singh , Luoyao Chen , Mei Chen , Jinqian Pan , Raviteja Chukkapalli , Shravan Chaudhari , Jacopo Cirrone

A central goal in deep learning is to learn compact representations of features at every layer of a neural network, which is useful for both unsupervised representation learning and structured network pruning. While there is a growing body…

Machine Learning · Computer Science 2021-10-05 Jie Bu , Arka Daw , M. Maruf , Anuj Karpatne

Most deep learning based image inpainting approaches adopt autoencoder or its variants to fill missing regions in images. Encoders are usually utilized to learn powerful representational spaces, which are important for dealing with…

Computer Vision and Pattern Recognition · Computer Science 2020-10-30 Xin Ma , Xiaoqiang Zhou , Huaibo Huang , Zhenhua Chai , Xiaolin Wei , Ran He

AI-enhanced segmentation of neuronal boundaries in electron microscopy (EM) images is crucial for automatic and accurate neuroinformatics studies. To enhance the limited generalization ability of typical deep learning frameworks for medical…

Computer Vision and Pattern Recognition · Computer Science 2023-05-05 Yuxiang An , Dongnan Liu , Weidong Cai

Cell classification and counting in immunohistochemical cytoplasm staining images play a pivotal role in cancer diagnosis. Weakly supervised learning is a potential method to deal with labor-intensive labeling. However, the inconstant cell…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Shichuan Zhang , Chenglu Zhu , Honglin Li , Jiatong Cai , Lin Yang

Medical image segmentation is a relevant problem, with deep learning being an exponent. However, the necessity of a high volume of fully annotated images for training massive models can be a problem, especially for applications whose images…

Computer Vision and Pattern Recognition · Computer Science 2024-06-06 Matheus A. Cerqueira , Flávia Sprenger , Bernardo C. A. Teixeira , Alexandre X. Falcão

The current study of cell architecture of inflammation in histopathology images commonly performed for diagnosis and research purposes excludes a lot of information available on the biopsy slide. In autoimmune diseases, major outstanding…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Pranav Singh , Jacopo Cirrone

The necessity of abundant annotated data and complex network architectures presents a significant challenge in deep-learning Salient Object Detection (deep SOD) and across the broader deep-learning landscape. This challenge is particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Felipe Crispim Salvagnini , Jancarlo F. Gomes , Cid A. N. Santos , Silvio Jamil F. Guimarães , Alexandre X. Falcão

Deep learning techniques have shown great potential in medical image processing, particularly through accurate and reliable image segmentation on magnetic resonance imaging (MRI) scans or computed tomography (CT) scans, which allow the…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Yang Liu , Ersi Zhang , Lulu Xu , Chufan Xiao , Xiaoyun Zhong , Lijin Lian , Fang Li , Bin Jiang , Yuhan Dong , Lan Ma , Qiming Huang , Ming Xu , Yongbing Zhang , Dongmei Yu , Chenggang Yan , Peiwu Qin

As the application of deep learning in dermatology continues to grow, the recognition of melanoma has garnered significant attention, demonstrating potential for improving diagnostic accuracy. Despite advancements in image classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rujosh Polma , Krishnan Menon Iyer

Accurate cell counting in microscopic images is important for medical diagnoses and biological studies. However, manual cell counting is very time-consuming, tedious, and prone to subjective errors. We propose a new density regression-based…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Shenghua He , Kyaw Thu Minn , Lilianna Solnica-Krezel , Hua Li , Mark Anastasio

Unsupervised domain adaptation (UDA) for nuclei instance segmentation is important for digital pathology, as it alleviates the burden of labor-intensive annotation and domain shift across datasets. In this work, we propose a Cycle…

Computer Vision and Pattern Recognition · Computer Science 2020-05-06 Dongnan Liu , Donghao Zhang , Yang Song , Fan Zhang , Lauren O'Donnell , Heng Huang , Mei Chen , Weidong Cai
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