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There is a need to develop Monte Carlo simulations of stroke to run in-silico trials to replace animal models, explore clinical scenarios to develop hypotheses for clinical studies and for interpreting clinical monitoring. We perform…
Local hemodynamic forces play an important role in determining the functional significance of coronary arterial stenosis and understanding the mechanism of coronary disease progression. Computational fluid dynamics (CFD) have been widely…
The clinical application of patient-specific modelling of the heart can provide valuable insights in supplementing and advancing methods of diagnosis as well as helping to devise the best possible therapeutic approach for each individual…
Numerical simulations of blood flow are a valuable tool to investigate the pathophysiology of ascending thoracic aortic aneurysms (ATAA). To accurately reproduce hemodynamics, computational fluid dynamics (CFD) models must employ realistic…
Numerous are the questionings raised by medicine interventionnelle, concerning the hold in charge of the pathologies of the arterial partition (aneurysm, dissection, coarctation, atherosclerosis).for it we made the modeling and the numeric…
Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…
This study presents a novel methodology for stratifying post-myocardial infarction patients at risk of ventricular arrhythmias using patient-specific 3D cardiac models derived from late gadolinium enhancement cardiovascular magnetic…
A deeper understanding of the influence of common cardiovascular diseases like stenosis, aneurysm or atherosclerosis on the circulatory mechanism is required, to establish new methods for early diagnosis. Different types of simulators were…
Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…
Computer simulations of blood flow in patients with anomalous aortic origin of a coronary artery (AAOCA) have the promise to provide insight into this complex disease. They provide an in-silico experimental platform to explore possible…
Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…
Computational ultrasound imaging (cUSi) with few elements and spatial field encoding can provide high-resolution volumetric B-mode imaging. In this work, we extend its application to 4D carotid artery (CA) flow imaging using a custom…
Many numerical studies of blood flow impose a rigid wall assumption due to the simplicity of its implementation compared to a full coupling to a solid mechanics model. In this paper, we present a localised method for incorporating the…
Computational fluid dynamics (CFD) is a valuable asset for patient-specific cardiovascular-disease diagnosis and prognosis, but its high computational demands hamper its adoption in practice. Machine-learning methods that estimate blood…
Background: For acute type-A aortic dissection (ATAAD) surgery, early post-surgery assessment is crucially important for effective treatment plans, underscoring the need for a framework to identify the risk level of aortic dissection cases.…
In this work, we investigate how concepts from medical flow visualization can be applied to enhance stroke prevention diagnostics. Our focus lies on carotid stenoses, i.e., local narrowings of the major brain-supplying arteries, which are a…
Coronary stent designs have undergone significant transformations in geometry, materials, and drug elution coatings, contributing to the continuous improvement of stenting success over recent decades. However, the increasing use of…
Purpose: To show some preliminary results about the possibility to exploit a cardiovascular mathematical model - made patient-specific by noninvasive data routinely measured during ordinary clinical examinations - in order to obtain…
Typical approaches to patient-specific hemodynamic studies of cerebral aneurysms use image based computational fluid dynamics (CFD) and seek to statistically correlate parameters such as wall shear stress (WSS) and oscillatory shear index…
Computational fluid dynamics (CFD) is a useful tool for prediction of turbulence in aerodynamic and biomedical applications. The choice of appropriate turbulence models is key to reaching accurate predictions. The present investigation…