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Higher-order information theory has become a rapidly growing toolkit in computational neuroscience, motivated by the idea that multivariate dependencies can reveal aspects of neural computation and communication that are invisible to…

Neurons and Cognition · Quantitative Biology 2025-12-03 D. Rebbin , K. J. A. Down , T. F. Varley , R. Ince , A. Canales-Johnson

Extracting higher-order structures from multivariate data has become an area of intensive study in complex systems science, as these multipartite interactions can reveal insights into fundamental features of complex systems like emergent…

Information Theory · Computer Science 2026-01-14 Thomas F. Varley

Pairwise metrics are often employed to estimate statistical dependencies between brain regions, however they do not capture higher-order information interactions. It is critical to explore higher-order interactions that go beyond paired…

Neurons and Cognition · Quantitative Biology 2023-08-04 Qiang Li , Shujian Yu , Kristoffer H Madsen , Vince D Calhoun , Armin Iraji

The application of the Shannon entropy to study the relationship between information and structures has yielded insights into molecular and material systems. However, the difficulty in directly observing and manipulating atoms and molecules…

In this paper, it is shown that the rank function of a matroid can be represented by a "mutual information function" if and only if the matroid is binary. The mutual information function considered is the one measuring the amount of…

Information Theory · Computer Science 2010-12-22 Emmanuel Abbe

This article introduces a model-agnostic approach to study statistical synergy, a form of emergence in which patterns at large scales are not traceable from lower scales. Our framework leverages various multivariate extensions of Shannon's…

Information Theory · Computer Science 2019-09-18 Fernando Rosas , Pedro A. M. Mediano , Michael Gastpar , Henrik J. Jensen

Information related measures are useful tools for multi variable data analysis, as measures of dependence among variables, and as descriptions of order in biological and physical systems. Information related measures, like marginal…

Information Theory · Computer Science 2016-09-27 David J. Galas , Nikita A. Sakhanenko

Distributed systems, such as biological and artificial neural networks, process information via complex interactions engaging multiple subsystems, resulting in high-order patterns with distinct properties across scales. Investigating how…

Information Theory · Computer Science 2025-04-23 Aaron J. Gutknecht , Fernando E. Rosas , David A. Ehrlich , Abdullah Makkeh , Pedro A. M. Mediano , Michael Wibral

We address the problem of efficiently and informatively quantifying how multiplets of variables carry information about the future of the dynamical system they belong to. In particular we want to identify groups of variables carrying…

Neurons and Cognition · Quantitative Biology 2020-08-03 Sebastiano Stramaglia , Tomas Scagliarini , Bryan C. Daniels , Daniele Marinazzo

Measures of dependence among variables, and measures of information content and shared information have become valuable tools of multi-variable data analysis. Information measures, like marginal entropies, mutual and multi-information, have…

Information Theory · Computer Science 2013-08-02 David J. Galas , Nikita A. Sakhanenko , Benjamin Keller

Information theoretic measures (entropies, entropy rates, mutual information) are nowadays commonly used in statistical signal processing for real-world data analysis. The present work proposes the use of Auto Mutual Information (Mutual…

Data Analysis, Statistics and Probability · Physics 2019-07-24 C Granero-Belinchón , S. Roux , P. Abry , N. Garnier

In information theory, one major goal is to find useful functions that summarize the amount of information contained in the interaction of several random variables. Specifically, one can ask how the classical Shannon entropy, mutual…

Information Theory · Computer Science 2025-02-14 Leon Lang , Pierre Baudot , Rick Quax , Patrick Forré

Quantifying the dependence between high-dimensional random variables is central to statistical learning and inference. Two classical methods are canonical correlation analysis (CCA), which identifies maximally correlated projected versions…

Machine Learning · Computer Science 2023-09-29 Dor Tsur , Ziv Goldfeld , Kristjan Greenewald

Estimating Mutual Information (MI), a key measure of dependence of random quantities without specific modelling assumptions, is a challenging problem in high dimensions. We propose a novel mutual information estimator based on parametrizing…

Machine Learning · Statistics 2025-10-24 Haoran Ni , Martin Lotz

Accurately determining dependency structure is critical to discovering a system's causal organization. We recently showed that the transfer entropy fails in a key aspect of this---measuring information flow---due to its conflation of dyadic…

Information Theory · Computer Science 2017-11-22 Ryan G. James , James P. Crutchfield

Conditional mutual information is important in the selection and interpretation of graphical models. Its empirical version is well known as a generalised likelihood ratio test and that it may be represented as a difference in entropy. We…

Methodology · Statistics 2015-01-20 Joe Whittaker , Florian Martin , Yang Xiang

$H$-mutual information ($H$-MI) is a wide class of information leakage measures, where $H=(\eta, F)$ is a pair of monotonically increasing function $\eta$ and a concave function $F$, which is a generalization of Shannon entropy. $H$-MI is…

Information Theory · Computer Science 2024-06-21 Akira Kamatsuka , Koki Kazama , Takahiro Yoshida

One of the most well-established tools for modeling the brain as a complex system is the functional connectivity network, which examines the correlations between pairs of interacting brain regions. While powerful, the network model is…

Information Theory · Computer Science 2022-06-15 Thomas F. Varley , Maria Pope , Joshua Faskowitz , Olaf Sporns

We establish a precise connection between statistical significance in dependence testing and information-theoretic dependence as quantified by Shannon mutual information (MI). In the absence of prior distributional information, we consider…

Statistics Theory · Mathematics 2026-02-02 Tsutomu Mori , Takashi Kawamura

Mutual information among three or more dimensions (mu-star = - Q) has been considered as interaction information. However, Krippendorff (2009a, 2009b) has shown that this measure cannot be interpreted as a unique property of the…

Information Retrieval · Computer Science 2010-01-08 Loet Leydesdorff
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