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Identifiability is a necessary condition for successful parameter estimation of dynamic system models. A major component of identifiability analysis is determining the identifiable parameter combinations, the functional forms for the…

Quantitative Methods · Quantitative Biology 2013-10-07 Marisa C. Eisenberg , Michael A. L. Hayashi

We consider the problem of selecting a small subset of representative variables from a large dataset. In the computer science literature, this dimensionality reduction problem is typically formalized as Column Subset Selection (CSS).…

Methodology · Statistics 2025-05-20 Anav Sood , Trevor Hastie

When employing mechanistic models to study biological phenomena, practical parameter identifiability is important for making accurate predictions across wide range of unseen scenarios, as well as for understanding the underlying mechanisms.…

Quantitative Methods · Quantitative Biology 2023-10-19 Yue Liu , Kevin Suh , Philip K. Maini , Daniel J. Cohen , Ruth E. Baker

Reliable predictions from systems biology models require knowing whether parameters can be estimated from available data, and with what certainty. Identifiability analysis reveals whether parameters are learnable in principle (structural…

Nonlinear system identification often involves a fundamental trade-off between interpretability and flexibility, often requiring the incorporation of physical constraints. We propose a unified data-driven framework that combines the…

Machine Learning · Computer Science 2025-09-16 Federico J. Gonzalez , Luis P. Lara

Sure Independence Screening is a fast procedure for variable selection in ultra-high dimensional regression analysis. Unfortunately, its performance greatly deteriorates with increasing dependence among the predictors. To solve this issue,…

Methodology · Statistics 2018-11-15 Yixin Wang , Stefan Van Aelst

Low rank matrix approximation is an important tool in machine learning. Given a data matrix, low rank approximation helps to find factors, patterns and provides concise representations for the data. Research on low rank approximation…

Computational Complexity · Computer Science 2017-04-21 Chen Dan , Kristoffer Arnsfelt Hansen , He Jiang , Liwei Wang , Yuchen Zhou

We present a novel and simple method to numerically calculate Fisher Information Matrices for stochastic chemical kinetics models. The linear noise approximation is used to derive model equations and a likelihood function which leads to an…

Applications · Statistics 2015-05-27 Michal Komorowski , Maria J. Costa , David A. Rand , Michael Stumpf

The quality of numerical reconstructions for unknown parameters in inverse problems depends fundamentally on the selection of experimental data. To ensure a robust reconstruction, it is crucial to select data that are sensitive to the…

Numerical Analysis · Mathematics 2026-04-14 Kathrin Hellmuth , Christian Klingenberg , Qin Li

Feature selection (FS) is a process which attempts to select more informative features. In some cases, too many redundant or irrelevant features may overpower main features for classification. Feature selection can remedy this problem and…

Machine Learning · Computer Science 2013-06-07 A. Nisthana Parveen , H. Hannah Inbarani , E. N. Sathishkumar

We consider the problem of matrix column subset selection, which selects a subset of columns from an input matrix such that the input can be well approximated by the span of the selected columns. Column subset selection has been applied to…

Machine Learning · Statistics 2018-01-26 Yining Wang , Aarti Singh

Scientists use mathematical modelling to understand and predict the properties of complex physical systems. In highly parameterised models there often exist relationships between parameters over which model predictions are identical, or…

Data Analysis, Statistics and Probability · Physics 2017-03-24 Dhruva V. Raman , James Anderson , Antonis Papachristodoulou

Its crux lies in the optimization of a tradeoff between accuracy and fairness of resultant models on the selected feature subset. The technical challenge of our setting is twofold: 1) streaming feature inputs, such that an informative…

Machine Learning · Computer Science 2024-08-26 Leizhen Zhang , Lusi Li , Di Wu , Sheng Chen , Yi He

The interactions between parameters, model structure, and outputs can determine what inferences, predictions, and control strategies are possible for a given system. Parameter space reduction and parameter estimation---and, more generally,…

Dynamical Systems · Mathematics 2018-02-16 Andrew F. Brouwer , Marisa C. Eisenberg

Spectrum Sensing (SS) is one of the most challenging issues in Cognitive Radio (CR) systems. Cooperative Spectrum Sensing (CSS) is proposed to enhance the detection reliability of a Primary User (PU) in fading environments. In this paper,…

Information Theory · Computer Science 2015-10-15 Hossam M. Farag , Ehab Mahmoud Mohamed

The selection of most informative and discriminative features from high-dimensional data has been noticed as an important topic in machine learning and data engineering. Using matrix factorization-based techniques such as nonnegative matrix…

Machine Learning · Computer Science 2022-10-04 Amir Moslemi , Arash Ahmadian

Linear causal models are important tools for modeling causal dependencies and yet in practice, only a subset of the variables can be observed. In this paper, we examine the parameter identifiability of these models by investigating whether…

Machine Learning · Computer Science 2025-02-11 Xinshuai Dong , Ignavier Ng , Biwei Huang , Yuewen Sun , Songyao Jin , Roberto Legaspi , Peter Spirtes , Kun Zhang

Practical identifiability is a critical concern in data-driven modeling of mathematical systems. In this paper, we propose a novel framework for practical identifiability analysis to evaluate parameter identifiability in mathematical models…

Quantitative Methods · Quantitative Biology 2026-01-06 Shun Wang , Wenrui Hao

This contribution presents a parameter identification methodology for the accurate and fast estimation of model parameters in a pseudo-two-dimensional (P2D) battery model. The methodology consists of three key elements. First, the data for…

Systems and Control · Electrical Eng. & Systems 2025-07-21 L. D. Couto , K. Haghverdi , F. Guo , K. Trad , G. Mulder

In this paper, we introduce an efficient algorithm for column subset selection that combines the column-pivoted QR factorization with sparse subspace embeddings. The proposed method, SE-QRSC, is particularly effective for wide matrices with…

Numerical Analysis · Mathematics 2025-09-05 Israa Fakih , Laura Grigori
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