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The ultimate goal of any sparse coding method is to accurately recover from a few noisy linear measurements, an unknown sparse vector. Unfortunately, this estimation problem is NP-hard in general, and it is therefore always approached with…

A central roadblock in the realization of variational quantum eigensolvers on quantum hardware is the high overhead associated with measurement repetitions, which hampers the computation of complex problems, such as the simulation of mid-…

Quantum Physics · Physics 2026-05-13 Davide Bincoletto , Jakob S. Kottmann

We present and apply a general-purpose, multi-start algorithm for improving the performance of low-energy samplers used for solving optimization problems. The algorithm iteratively fixes the value of a large portion of the variables to…

Discrete Mathematics · Computer Science 2017-11-02 Hamed Karimi , Gili Rosenberg , Helmut G. Katzgraber

The Coherent Ising Machine (CIM) is a quantum network of optical parametric oscillators (OPOs) intended to find ground states of the Ising model. This is an NP-hard problem, related to several important minimization problems, including the…

The recent emergence of novel computational devices, such as quantum computers, coherent Ising machines, and digital annealers presents new opportunities for hardware-accelerated hybrid optimization algorithms. Unfortunately, demonstrations…

Optimization and Control · Mathematics 2020-10-21 Yuchen Pang , Carleton Coffrin , Andrey Y. Lokhov , Marc Vuffray

We analyze a numerical method to solve the time-dependent linear Pauli equation in three space dimensions. The Pauli equation is a semi-relativistic generalization of the Schr\"odinger equation for 2-spinors which accounts both for magnetic…

Numerical Analysis · Mathematics 2023-04-05 Timon S. Gutleb , Norbert J. Mauser , Michele Ruggeri , Hans Peter Stimming

The computational equivalence between approximate counting and sampling is well established for polynomial-time algorithms. The most efficient general reduction from counting to sampling is achieved via simulated annealing, where the…

Data Structures and Algorithms · Computer Science 2026-04-03 David G. Harris , Vladimir Kolmogorov , Hongyang Liu , Yitong Yin , Yiyao Zhang

Processing large Pauli sums is a significant bottleneck in quantum chemistry, Pauli propagation, and Pauli-based compilation. Existing frameworks often suffer from Python interpreter overhead or utilize hash-map data structures that hinder…

Quantum Physics · Physics 2026-05-26 Florian Krötz

Ising Machines are emerging hardware architectures that efficiently solve NP-Hard combinatorial optimization problems. Generally, combinatorial problems are transformed into quadratic unconstrained binary optimization (QUBO) form, but this…

Hardware Architecture · Computer Science 2025-09-12 Chirag Garg , Sayeef Salahuddin

Partitioning is a well studied research problem in the area of VLSI physical design automation. In this problem, input is an integrated circuit and output is a set of almost equal disjoint blocks. The main objective of partitioning is to…

Data Structures and Algorithms · Computer Science 2014-03-04 Mitali Sinha , Suchismita Pattanaik , Rakesh Mohanty , Prachi Tripathy

This paper presents Sparse Partitioning, a Bayesian method for identifying predictors that either individually or in combination with others affect a response variable. The method is designed for regression problems involving binary or…

Quantitative Methods · Quantitative Biology 2011-08-31 Doug Speed , Simon Tavaré

We introduce an optimisation method for variational quantum algorithms and experimentally demonstrate a 100-fold improvement in efficiency compared to naive implementations. The effectiveness of our approach is shown by obtaining…

In this work we investigate the capabilities of a hybrid quantum-classical procedure to explore the solution space using the D-Wave $2000Q^{TM}$ Quantum Annealer device. Here we study the ability of the Quantum hardware to solve the Number…

Quantum Physics · Physics 2020-03-10 Luca Asproni , Davide Caputo , Blanca Silva , Giovanni Fazzi , Marco Magagnini

We present a software library for the commutation of Pauli operators through quantum Clifford circuits, which is called Pauli tracking. Tracking Pauli operators allows one to reduce the number of Pauli gates that must be executed on quantum…

Quantum Physics · Physics 2024-11-22 Jannis Ruh , Simon Devitt

Sampling Boltzmann probability distributions plays a key role in machine learning and optimization, motivating the design of hardware accelerators such as Ising machines. While the Ising model can in principle encode arbitrary optimization…

Machine Learning · Computer Science 2025-08-01 Corentin Delacour , M Mahmudul Hasan Sajeeb , Joao P. Hespanha , Kerem Y. Camsari

We present a near-optimal reduction from approximately counting the cardinality of a discrete set to approximately sampling elements of the set. An important application of our work is to approximating the partition function $Z$ of a…

Data Structures and Algorithms · Computer Science 2007-05-23 Daniel Stefankovic , Santosh Vempala , Eric Vigoda

Drawing independent samples from high-dimensional probability distributions represents the major computational bottleneck for modern algorithms, including powerful machine learning frameworks such as deep learning. The quest for discovering…

Quantum Physics · Physics 2022-10-13 Marc Vuffray , Carleton Coffrin , Yaroslav A. Kharkov , Andrey Y. Lokhov

Decomposing a matrix into a weighted sum of Pauli strings is a common chore of the quantum computer scientist, whom is not easily discouraged by exponential scaling. But beware, a naive decomposition can be cubically more expensive than…

Quantum Physics · Physics 2024-01-31 Tyson Jones

The main objective of this paper is to solve the optimization problem that is associated with the classification of DNA samples in PCR plates for Sanger sequencing. To achieve this goal, we design an integer linear programming model. Given…

Data Structures and Algorithms · Computer Science 2024-01-23 Luisa Carpente , Ana Cerdeira-Pena , Silvia Lorenzo-Freire , Ángeles S. Places

The recent emergence of novel computational devices, such as adiabatic quantum computers, CMOS annealers, and optical parametric oscillators, present new opportunities for hybrid-optimization algorithms that are hardware accelerated by…

Optimization and Control · Mathematics 2019-06-20 Carleton Coffrin , Harsha Nagarajan , Russell Bent