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Related papers: An age-structured epidemic model with vaccination

200 papers

The COVID-19 epidemic has been spreading around the world for nearly three years, and asymptomatic infections have exacerbated the spread of the epidemic. To evaluate the role of asymptomatic infections in the spread of the epidemic, we…

Analysis of PDEs · Mathematics 2022-10-25 ZH. Zhang , XT. Huang , KD. Cheng , CQ. Xu , SB. Guo , XJ. Wang

We present a stochastic epidemic model to study the effect of various preventive measures, such as uniform reduction of contacts and transmission, vaccination, isolation, screening and contact tracing, on a disease outbreak in a…

Populations and Evolution · Quantitative Biology 2022-07-08 Martina Favero , Gianpaolo Scalia Tomba , Tom Britton

The waning of immunity after recovery or vaccination is a major factor accounting for the severity and prolonged duration of an array of epidemics, ranging from COVID-19 to diphtheria and pertussis. To study the effectiveness of different…

Dynamical Systems · Mathematics 2023-02-01 Shoshana Elgart

We use a simple SIR-like epidemic model which integrates known age-contact patterns for the United States to model the effect of age-targeted mitigation strategies for a COVID-19-like epidemic. We find that, among strategies which end with…

Populations and Evolution · Quantitative Biology 2020-09-09 Maria Chikina , Wesley Pegden

The outbreak of a novel coronavirus causing severe acute respiratory syndrome in December 2019 has escalated into a worldwide pandemic. In this work, we propose a compartmental model to describe the dynamics of transmission of infection and…

Optimization and Control · Mathematics 2022-10-25 Eleni Zavrakli , Andrew Parnell , David Malone , Ken Duffy , Subhrakanti Dey

This study examines the effect of a partially protective vaccine on COVID-19 infection with the original and mutant virus with the help of a deterministic mathematical model developed. The model we developed consists of five compartments…

Dynamical Systems · Mathematics 2024-12-11 Ceren Gürbüz Can , Sebaheddin Şevgin

Motivated by the issue of COVID-19 mitigation, in this work we tackle the general problem of optimally controlling an epidemic outbreak of a communicable disease structured by time since exposure, by the aid of two types of control…

Populations and Evolution · Quantitative Biology 2024-05-13 Alberto d'Onofrio , Mimmo Iannelli , Piero Manfredi , Gabriela Marinoschi

We evaluate the efficiency of various heuristic strategies for allocating vaccines against COVID-19 and compare them to strategies found using optimal control theory. Our approach is based on a mathematical model which tracks the spread of…

Populations and Evolution · Quantitative Biology 2022-05-04 Jeta Molla , Alejandro Ponce de León Chávez , Takayuki Hiraoka , Tapio Ala-Nissila , Mikko Kivelä , Lasse Leskelä

Motivated by massive outbreaks of COVID-19 that occurred even in populations with high vaccine uptake, we propose a novel multi-population temporal network model for the spread of recurrent epidemic diseases. We study the effect of human…

Dynamical Systems · Mathematics 2022-09-19 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

The goal of this work is to develop and analyze a reaction-diffusion model for the transmission dynamics of the Coronavirus (COVID-19) that accounts for reinfection and vaccination, as well as to compare it to the ODE model. After…

Analysis of PDEs · Mathematics 2025-05-01 Hamadjam Abboubakar , Reinhard Racke , Nicolas Schlosser

We study global dynamics of an SIR model with vaccination, where we assume that individuals respond differently to dynamics of the epidemic. Their heterogeneous response is modeled by the Preisach hysteresis operator. We present a condition…

Dynamical Systems · Mathematics 2020-07-10 Jana Kopfová , Petra Nábělková , D. Rachinskii , S. Rouf

A pandemic, the worldwide spread of a disease, can threaten human beings from the social as well as biological perspectives and paralyze existing living habits. To stave off the more devastating disaster and return to a normal life, people…

Physics and Society · Physics 2022-07-25 Gyeong Hwan Jang , Sung Jin Kim , Mi Jin Lee , Seung-Woo Son

Inspired by contagion models of social belief formation, we develop an epistemically-informed modeling framework, SIS-Vo, in which vaccine-related information propagates on a signed opinion network. Our model allows for heterogeneous…

Physics and Society · Physics 2026-05-22 Alessandro Casu , Camilla Quaresmini , Robin Delabays , Lewis Mitchell , Philip E. Paré

In this paper we propose a macro-dynamic age-structured set-up for the analysis of epidemics/economic dynamics in continuous time. The resulting optimal control problem is reformulated in an infinite dimensional Hilbert space framework…

Theoretical Economics · Economics 2020-08-18 Giorgio Fabbri , Fausto Gozzi , Giovanni Zanco

The Covid-19 outbreak of 2020 has required many governments to develop and adopt mathematical-statistical models of the pandemic for policy and planning purposes. To this end, this work provides a tutorial on building a compartmental model…

Applications · Statistics 2023-09-13 Elizabeth B Amona , Ryad A Ghanam , Edward L Boone , Indranil Sahoo , Laith J Abu-Raddad

In this paper, we consider a compartmental SIRS epidemic model with asymptomatic infection and seasonal succession, which is a periodic discontinuous differential system. The basic reproduction number $\mathcal{R}_0$ is defined and valuated…

Dynamical Systems · Mathematics 2017-08-15 Yilei Tang , Dongmei Xiao , Weinian Zhang , Di Zhu

A mathematical model of COVID-19 with minimal compartments is developed. The model is simple enough to fit data on confirmed cases, estimate the hidden infection figure and incorporate the effect of vaccination. With the effect of the new…

Populations and Evolution · Quantitative Biology 2021-03-05 Randy L. Caga-anan , Michelle N. Raza , Grace Shelda G. Labrador , Ephrime B. Metillo

In this paper we investigate the asymptotic behavior of some SIR models incorporating demography, bounded random transmission coefficient and a time-dependent vaccination strategy targeting the susceptible population. In this setting, we…

Populations and Evolution · Quantitative Biology 2025-10-27 Javier López-de-la-Cruz , Susana Merchán , Felipe Rivero , Javier Rodrigo

SIR models, also with age structure, can be used to describe the evolution of an infective disease. A vaccination campaign influences this dynamics immunizing part of the susceptible individuals, essentially turning them into recovered…

Analysis of PDEs · Mathematics 2019-10-17 Rinaldo M. Colombo , Mauro Garavello

We consider an epidemiological SIR model with an infection rate depending on the recovered population. We establish sufficient conditions for existence, uniqueness, and stability (local and global) of endemic equilibria and consider also…

Classical Analysis and ODEs · Mathematics 2021-07-09 Andres David Báez-Sánchez , Nara Bobko