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Recent developed graph-based methods for diagnosing brain disorders using functional connectivity highly rely on predefined brain atlases, but overlook the rich information embedded within atlases and the confounding effects of site and…

Machine Learning · Computer Science 2025-10-16 Qianqian Liao , Wuque Cai , Hongze Sun , Dongze Liu , Duo Chen , Dezhong Yao , Daqing Guo

Empowered by semantic-rich content information, multimedia recommendation has emerged as a potent personalized technique. Current endeavors center around harnessing multimedia content to refine item representation or uncovering latent…

Information Retrieval · Computer Science 2025-01-22 Yonghui Yang , Le Wu , Zhuangzhuang He , Zhengwei Wu , Richang Hong , Meng Wang

In the past decade, deep neural networks have seen unparalleled improvements that continue to impact every aspect of today's society. With the development of high performance GPUs and the availability of vast amounts of data, learning…

Machine Learning · Computer Science 2021-05-12 Mohammad Ali Alomrani

Functional magnetic resonance imaging (fMRI) reveals complex brain functional networks with hierarchical topologies crucial for cognitive processing. Standard Euclidean Graph Neural Networks (GNNs) often struggle to represent these…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Junhao Jia , Yunyou Liu , Cheng Yang , Yifei Sun , Feiwei Qin , Changmiao Wang , Yong Peng

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Alzheimer's disease progression prediction is critical for patients with early Mild Cognitive Impairment (MCI) to enable timely intervention and improve their quality of life. While existing progression prediction techniques demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Zhongying Deng , Shujun Wang , Angelica I Aviles-Rivero , Zoe Kourtzi , Carola-Bibiane Schönlieb

Cognitive task classification using machine learning plays a central role in decoding brain states from neuroimaging data. By integrating machine learning with brain network analysis, complex connectivity patterns can be extracted from…

Machine Learning · Computer Science 2026-01-01 Debasis Maji , Arghya Banerjee , Debaditya Barman

Despite their success in various domains, the growing dependence on GNNs raises a critical concern about the nature of the combinatorial reasoning underlying their predictions, which is often hidden within their black-box architectures.…

Machine Learning · Computer Science 2026-03-03 Yue Niu , Zhaokai Sun , Jiayi Yang , Xiaofeng Cao , Rui Fan , Xin Sun , Hanli Wang , Wei Ye

Graph neural networks (GNNs) provide powerful insights for brain neuroimaging technology from the view of graphical networks. However, most existing GNN-based models assume that the neuroimaging-produced brain connectome network is a…

Machine Learning · Computer Science 2022-09-30 Gen Shi , Yifan Zhu , Wenjin Liu , Quanming Yao , Xuesong Li

The Information Bottleneck (IB) method is an information theoretical framework to design a parsimonious and tunable feature-extraction mechanism, such that the extracted features are maximally relevant to a specific learning or inference…

Signal Processing · Electrical Eng. & Systems 2024-04-17 Francesco Binucci , Paolo Banelli , Paolo Di Lorenzo , Sergio Barbarossa

Several brain disorders can be detected by observing alterations in the brain's structural and functional connectivities. Neurological findings suggest that early diagnosis of brain disorders, such as mild cognitive impairment (MCI), can…

Neurons and Cognition · Quantitative Biology 2021-10-22 Alpay Tekin , Ahmed Nebli , Islem Rekik

Brain graph representation learning serves as the fundamental technique for brain diseases diagnosis. Great efforts from both the academic and industrial communities have been devoted to brain graph representation learning in recent years.…

Machine Learning · Computer Science 2022-06-28 Jiawei Zhang

Graph Neural Networks (GNNs) have received increasing attention due to their ability to learn from graph-structured data. To open the black-box of these deep learning models, post-hoc instance-level explanation methods have been proposed to…

Machine Learning · Computer Science 2024-02-08 Rundong Huang , Farhad Shirani , Dongsheng Luo

Data-driven approaches for depression diagnosis have emerged as a significant research focus in neuromedicine, driven by the development of relevant datasets. Recently, graph neural network (GNN)-based models have gained widespread adoption…

Machine Learning · Computer Science 2025-05-01 Chengkai Yang , Xingping Dong , Xiaofen Zong

Information Bottleneck (IB) is a generalization of rate-distortion theory that naturally incorporates compression and relevance trade-offs for learning. Though the original IB has been extensively studied, there has not been much…

Machine Learning · Computer Science 2019-10-08 Thanh T. Nguyen , Jaesik Choi

Interpretable brain network models for disease prediction are of great value for the advancement of neuroscience. GNNs are promising to model complicated network data, but they are prone to overfitting and suffer from poor interpretability,…

Machine Learning · Computer Science 2021-07-13 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

Early diagnosis and discovery of therapeutic drug targets are crucial objectives for effective management of Alzheimer's Disease (AD). Current approaches for AD diagnosis and treatment planning are based on radiological imaging and largely…

Machine Learning · Computer Science 2026-05-01 Maryam Khalid , Fadeel Sher Khan , John Broussard , Arko Barman

Mining discriminative subgraph patterns from graph data has attracted great interest in recent years. It has a wide variety of applications in disease diagnosis, neuroimaging, etc. Most research on subgraph mining focuses on the graph…

Machine Learning · Computer Science 2016-11-15 Bokai Cao , Xiangnan Kong , Jingyuan Zhang , Philip S. Yu , Ann B. Ragin

The Information Bottleneck (IB) principle has emerged as a promising approach for enhancing the generalization, robustness, and interpretability of deep neural networks, demonstrating efficacy across image segmentation, document clustering,…

Information Theory · Computer Science 2025-04-18 Hanzhe Yang , Youlong Wu , Dingzhu Wen , Yong Zhou , Yuanming Shi

Functional Magnetic Resonance Image (fMRI) is commonly employed to study human brain activity, since it offers insight into the relationship between functional fluctuations and human behavior. To enhance analysis and comprehension of brain…

Artificial Intelligence · Computer Science 2025-02-04 Song Wang , Zhenyu Lei , Zhen Tan , Jiaqi Ding , Xinyu Zhao , Yushun Dong , Guorong Wu , Tianlong Chen , Chen Chen , Aiying Zhang , Jundong Li