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The development of diagnostic models is gaining traction in the field of psychiatric disorders. Recently, machine learning classifiers based on resting-state functional magnetic resonance imaging (rs-fMRI) have been developed to identify…

Machine Learning · Computer Science 2025-10-06 Tianzheng Hu , Qiang Li , Shu Liu , Vince D. Calhoun , Guido van Wingen , Shujian Yu

Developing interpretable models for neurodevelopmental disorders (NDDs) diagnosis presents significant challenges in effectively encoding, decoding, and integrating multimodal neuroimaging data. While many existing machine learning…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Yueyang Li , Lei Chen , Wenhao Dong , Shengyu Gong , Zijian Kang , Boyang Wei , Weiming Zeng , Hongjie Yan , Lingbin Bian , Zhiguo Zhang , Wai Ting Siok , Nizhuan Wang

Given the input graph and its label/property, several key problems of graph learning, such as finding interpretable subgraphs, graph denoising and graph compression, can be attributed to the fundamental problem of recognizing a subgraph of…

Machine Learning · Computer Science 2020-10-13 Junchi Yu , Tingyang Xu , Yu Rong , Yatao Bian , Junzhou Huang , Ran He

Mapping the connectome of the human brain using structural or functional connectivity has become one of the most pervasive paradigms for neuroimaging analysis. Recently, Graph Neural Networks (GNNs) motivated from geometric deep learning…

Neurons and Cognition · Quantitative Biology 2022-11-30 Hejie Cui , Wei Dai , Yanqiao Zhu , Xuan Kan , Antonio Aodong Chen Gu , Joshua Lukemire , Liang Zhan , Lifang He , Ying Guo , Carl Yang

The success of Graph Neural Networks (GNNs) has led to a need for understanding their decision-making process and providing explanations for their predictions, which has given rise to explainable AI (XAI) that offers transparent…

Machine Learning · Computer Science 2024-02-21 Sangwoo Seo , Sungwon Kim , Chanyoung Park

Subgraph recognition aims at discovering a compressed substructure of a graph that is most informative to the graph property. It can be formulated by optimizing Graph Information Bottleneck (GIB) with a mutual information estimator.…

Machine Learning · Computer Science 2022-04-05 Junchi Yu , Jie Cao , Ran He

Representation learning of graph-structured data is challenging because both graph structure and node features carry important information. Graph Neural Networks (GNNs) provide an expressive way to fuse information from network structure…

Machine Learning · Computer Science 2020-10-27 Tailin Wu , Hongyu Ren , Pan Li , Jure Leskovec

The emergence of Graph Convolutional Network (GCN) has greatly boosted the progress of graph learning. However, two disturbing factors, noise and redundancy in graph data, and lack of interpretation for prediction results, impede further…

Machine Learning · Computer Science 2021-03-23 Junchi Yu , Tingyang Xu , Yu Rong , Yatao Bian , Junzhou Huang , Ran He

Dynamic Graphs widely exist in the real world, which carry complicated spatial and temporal feature patterns, challenging their representation learning. Dynamic Graph Neural Networks (DGNNs) have shown impressive predictive abilities by…

Machine Learning · Computer Science 2024-04-09 Haonan Yuan , Qingyun Sun , Xingcheng Fu , Cheng Ji , Jianxin Li

Due to the superior performance of Graph Neural Networks (GNNs) in various domains, there is an increasing interest in the GNN explanation problem "\emph{which fraction of the input graph is the most crucial to decide the model's…

Machine Learning · Computer Science 2022-07-04 Qinghua Zheng , Jihong Wang , Minnan Luo , Yaoliang Yu , Jundong Li , Lina Yao , Xiaojun Chang

Graph Neural Networks (GNNs) have gained considerable traction for their capability to effectively process topological data, yet their interpretability remains a critical concern. Current interpretation methods are dominated by post-hoc…

Machine Learning · Computer Science 2024-02-08 Jiahua Rao , Jiancong Xie , Hanjing Lin , Shuangjia Zheng , Zhen Wang , Yuedong Yang

Deep neural networks (DNNs) have demonstrated remarkable performance across various domains, but their inherent complexity makes them challenging to interpret. This is especially true for temporal graph regression tasks due to the complex…

Machine Learning · Computer Science 2025-12-30 Ali Royat , Seyed Mohamad Moghadas , Lesley De Cruz , Adrian Munteanu

Human brains lie at the core of complex neurobiological systems, where the neurons, circuits, and subsystems interact in enigmatic ways. Understanding the structural and functional mechanisms of the brain has long been an intriguing pursuit…

Neurons and Cognition · Quantitative Biology 2022-07-26 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

Nearly one in five adolescents currently live with a diagnosed mental or behavioral health condition, such as anxiety, depression, or conduct disorder, underscoring the urgency of developing accurate and interpretable diagnostic tools.…

Machine Learning · Computer Science 2025-10-07 Song Wang , Zhenyu Lei , Zhen Tan , Jundong Li , Javier Rasero , Aiying Zhang , Chirag Agarwal

This study aims to build a pre-trained Graph Neural Network (GNN) model on molecules without human annotations or prior knowledge. Although various attempts have been proposed to overcome limitations in acquiring labeled molecules, the…

Machine Learning · Computer Science 2024-12-23 Van Thuy Hoang , O-Joun Lee

The Information Bottleneck (IB) principle offers a compelling theoretical framework to understand how neural networks (NNs) learn. However, its practical utility has been constrained by unresolved theoretical ambiguities and significant…

Machine Learning · Computer Science 2026-02-02 Charles Westphal , Stephen Hailes , Mirco Musolesi

Recent studies have revealed that GNNs are vulnerable to adversarial attacks. Most existing robust graph learning methods measure model robustness based on label information, rendering them infeasible when label information is not…

Machine Learning · Computer Science 2023-06-09 Jihong Wang , Minnan Luo , Jundong Li , Ziqi Liu , Jun Zhou , Qinghua Zheng

Although deep neural networks have been immensely successful, there is no comprehensive theoretical understanding of how they work or are structured. As a result, deep networks are often seen as black boxes with unclear interpretations and…

Machine Learning · Computer Science 2022-02-22 Ravid Shwartz-Ziv

Recent years have seen a surge in research focused on leveraging graph learning techniques to detect neurodegenerative diseases. However, existing graph-based approaches typically lack the ability to localize and extract the specific brain…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Nguyen Linh Dan Le , Jing Ren , Ciyuan Peng , Chengyao Xie , Bowen Li , Feng Xia

In recent years, functional magnetic resonance imaging has emerged as a powerful tool for investigating the human brain's functional connectivity networks. Related studies demonstrate that functional connectivity networks in the human brain…

Artificial Intelligence · Computer Science 2023-09-18 Xiangzhu Meng , Wei Wei , Qiang Liu , Shu Wu , Liang Wang
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