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Deformable image registration remains a central challenge in medical image analysis, particularly under multi-modal scenarios where intensity distributions vary significantly across scans. While deep learning methods provide efficient…

Image and Video Processing · Electrical Eng. & Systems 2026-03-30 Yi Zhang , Yidong Zhao , Qian Tao

Image-guided interventions are saving the lives of a large number of patients where the image registration problem should indeed be considered as the most complex and complicated issue to be tackled. On the other hand, the recently huge…

Image and Video Processing · Electrical Eng. & Systems 2020-08-14 Hamid Reza Boveiri , Raouf Khayami , Reza Javidan , Ali Reza MehdiZadeh

As in other areas of medical image analysis, e.g. semantic segmentation, deep learning is currently driving the development of new approaches for image registration. Multi-scale encoder-decoder network architectures achieve state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Lasse Hansen , Mattias P. Heinrich

One of the fundamental challenges in supervised learning for multimodal image registration is the lack of ground-truth for voxel-level spatial correspondence. This work describes a method to infer voxel-level transformation from…

Accurate intraoperative image guidance is critical for achieving maximal safe resection in brain tumor surgery, yet neuronavigation systems based on preoperative MRI lose accuracy during the procedure due to brain shift. Aligning…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Reuben Dorent , Laura Rigolo , Colin P. Galvin , Junyu Chen , Mattias P. Heinrich , Aaron Carass , Olivier Colliot , Demian Wassermann , Alexandra Golby , Tina Kapur , William Wells

Deformable image registration (alignment) is highly sought after in numerous clinical applications, such as computer aided diagnosis and disease progression analysis. Deep Convolutional Neural Network (DCNN)-based image registration methods…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Ruizhe Li , Grazziela Figueredo , Dorothee Auer , Christian Wagner , Xin Chen

Art technological investigations of historical panel paintings rely on acquiring multi-modal image data, including visual light photography, infrared reflectography, ultraviolet fluorescence photography, x-radiography, and macro…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Aline Sindel , Andreas Maier , Vincent Christlein

Deformable image registration is a fundamental task in medical image analysis and plays a crucial role in a wide range of clinical applications. Recently, deep learning-based approaches have been widely studied for deformable medical image…

Image and Video Processing · Electrical Eng. & Systems 2023-07-03 Jing Zou , Noémie Debroux , Lihao Liu , Jing Qin , Carola-Bibiane Schönlieb , Angelica I Aviles-Rivero

The diagnosis of prostate cancer increasingly depends on multimodal imaging, particularly magnetic resonance imaging (MRI) and transrectal ultrasound (TRUS). However, accurate registration between these modalities remains a fundamental…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Xudong Ma , Nantheera Anantrasirichai , Stefanos Bolomytis , Alin Achim

Recent deep learning-based methods have shown promising results and runtime advantages in deformable image registration. However, analyzing the effects of hyperparameters and searching for optimal regularization parameters prove to be too…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Tony C. W. Mok , Albert C. S. Chung

Deep neural networks are increasingly used for pair-wise image registration. We propose to extend current learning-based image registration to allow simultaneous registration of multiple images. To achieve this, we build upon the pair-wise…

Image and Video Processing · Electrical Eng. & Systems 2020-10-02 Tycho F. A. van der Ouderaa , Ivana Išgum , Wouter B. Veldhuis , Bob D. de Vos

Classical deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu

Real-time 3D navigation during minimally invasive procedures is an essential yet challenging task, especially when considerable tissue motion is involved. To balance image acquisition speed and resolution, only 2D images or low-resolution…

Computer Vision and Pattern Recognition · Computer Science 2018-01-03 Xiao-Yun Zhou , Guang-Zhong Yang , Su-Lin Lee

Advanced navigation techniques in image-guided interventions and surgical robotics require the rapid and precise alignment of 3D preoperative volumes (e.g., CT, MRI) to 2D intraoperative images (e.g., X-ray fluoroscopy). However, existing…

Conventional approaches to image registration consist of time consuming iterative methods. Most current deep learning (DL) based registration methods extract deep features to use in an iterative setting. We propose an end-to-end DL method…

Computer Vision and Pattern Recognition · Computer Science 2019-09-11 Dwarikanath Mahapatra

We describe a point-set registration algorithm based on a novel free point transformer (FPT) network, designed for points extracted from multimodal biomedical images for registration tasks, such as those frequently encountered in…

Computer Vision and Pattern Recognition · Computer Science 2020-08-06 Zachary M. C. Baum , Yipeng Hu , Dean C. Barratt

Medical image registration is crucial for various clinical and research applications including disease diagnosis or treatment planning which require alignment of images from different modalities, time points, or subjects. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Ahsan Raza Siyal , Markus Haltmeier , Ruth Steiger , Malik Galijasevic , Elke Ruth Gizewski , Astrid Ellen Grams

The establishment of image correspondence through robust image registration is critical to many clinical tasks such as image fusion, organ atlas creation, and tumor growth monitoring, and is a very challenging problem. Since the beginning…

Quantitative Methods · Quantitative Biology 2020-01-22 Grant Haskins , Uwe Kruger , Pingkun Yan

Standard registration algorithms need to be independently applied to each surface to register, following careful pre-processing and hand-tuning. Recently, learning-based approaches have emerged that reduce the registration of new scans to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Mehdi Bahri , Eimear O' Sullivan , Shunwang Gong , Feng Liu , Xiaoming Liu , Michael M. Bronstein , Stefanos Zafeiriou

Accurately registering breast MR images from different time points enables the alignment of anatomical structures and tracking of tumor progression, supporting more effective breast cancer detection, diagnosis, and treatment planning.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-01 Yaqian Chen , Hanxue Gu , Haoyu Dong , Qihang Li , Yuwen Chen , Nicholas Konz , Lin Li , Maciej A. Mazurowski
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