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Speculative decoding enhances the inference efficiency of large language models (LLMs) by generating drafts using a small draft language model (DLM) and verifying them in batches with a large target language model (TLM). However, adaptive…

Hardware Architecture · Computer Science 2026-05-01 Ma Zirui , Fan Zhihua , Li Wenxing , Wu Haibin , Zhang Fulin , Ye Xiaochun , Li Wenming

Machine learning has achieved remarkable success over the past couple of decades, often attributed to a combination of algorithmic innovations and the availability of high-quality data available at scale. However, a third critical component…

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of…

Hyperparameter Optimization (HPO) can lift the burden of tuning hyperparameters (HPs) of neural networks. HPO algorithms from the Population Based Training (PBT) family are efficient thanks to dynamically adjusting HPs every few steps of…

Machine Learning · Computer Science 2025-11-13 Alexander Chebykin , Tanja Alderliesten , Peter A. N. Bosman

Although deep learning-based personalized recommendation systems provide qualified recommendations, they strain data center resources. The main bottleneck is the embedding layer, which is highly memory-intensive due to its sparse, irregular…

Hardware Architecture · Computer Science 2025-11-26 Youngsuk Kim , Junghwan Lim , Hyuk-Jae Lee , Chae Eun Rhee

PSO is a widely recognized optimization algorithm inspired by social swarm. In this brief we present a heterogeneous strategy particle swarm optimization (HSPSO), in which a proportion of particles adopt a fully informed strategy to enhance…

Neural and Evolutionary Computing · Computer Science 2016-08-02 Wen-Bo Du , Wen Ying , Gang Yan , Yan-Bo Zhu , Xian-Bin Cao

Genetic algorithm (GA) is a stochastic metaheuristic process consisting on the evolution of a population of candidate solutions for a given optimization problem. By extension, multipopulation genetic algorithm (MPGA) aims for efficiency by…

Neural and Evolutionary Computing · Computer Science 2018-06-07 Bruno Messias , Bruno W. D. Morais

The beam alignment (BA) problem consists in accurately aligning the transmitter and receiver beams to establish a reliable communication link in wireless communication systems. Existing BA methods search the entire beam space to identify…

Information Theory · Computer Science 2022-10-25 Yi Wei , Zixin Zhong , Vincent Y. F. Tan

Adaptive indexing is a concept that considers index creation in databases as a by-product of query processing; as opposed to traditional full index creation where the indexing effort is performed up front before answering any queries.…

Databases · Computer Science 2014-04-09 Victor Alvarez , Felix Martin Schuhknecht , Jens Dittrich , Stefan Richter

In this talk I discuss the general question of the portability of Molecular Dynamics codes for diffusive systems on parallel computers of the APE family. The intrinsic single precision arithmetics of the today available APE platforms does…

Biological Physics · Physics 2009-10-30 G. La Penna , S. Letardi , V. Minicozzi , S. Morante , G. C. Rossi , G. Salina

Frontier models increasingly adopt Mixture-of-Experts (MoE) architectures to achieve large-model performance at reduced cost. However, training MoE models on HPC platforms is hindered by large memory footprints, frequent large-scale…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-07 Sajal Dash , Feiyi Wang

Genome assembly from the high-throughput sequencing (HTS) reads is a fundamental yet challenging computational problem. An intrinsic challenge is the uncertainty caused by the widespread repetitive elements. Here we get around the…

Genomics · Quantitative Biology 2016-09-13 Anqi Wang , Zheng Li , Zhanyu Wang , Lei M. Li

The use of FPGAs for efficient graph processing has attracted significant interest. Recent memory subsystem upgrades including the introduction of HBM in FPGAs promise to further alleviate memory bottlenecks. However, modern multi-channel…

Hardware Architecture · Computer Science 2022-03-08 Xinyu Chen , Yao Chen , Feng Cheng , Hongshi Tan , Bingsheng He , Weng-Fai Wong

In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent…

Methodology · Statistics 2019-03-27 Naim U. Rashid , Quefeng Li , Jen Jen Yeh , Joseph G. Ibrahim

While graph-based dynamic programming (DP) is a cornerstone of genomics and network analytics, its efficiency is hampered by fundamentally conflicting computational patterns. Matrix-centric DP drives regular, compute-bound network…

Hardware Architecture · Computer Science 2026-04-20 Yanru Chen , Runyang Tian , Zheyu Li , Mahbod Afarin , Weihong Xu , Tajana Rosing

The importance of the use of networks to model and analyse biological data and the interplay of bio-molecules is widely recognised. Consequently, many algorithms for the analysis and the comparison of networks (such as alignment algorithms)…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-06-12 Pietro H Guzzi , Marianna Milano , Pierangelo Veltri , Mario Cannataro

The proliferation of heterogeneous chip multiprocessors in recent years has reached unprecedented levels. Traditional homogeneous platforms have shown fundamental limitations when it comes to enabling high-performance yet-ultra-low-power…

Evolutionary computing, particularly genetic algorithm (GA), is a combinatorial optimization method inspired by natural selection and the transmission of genetic information, which is widely used to identify optimal solutions to complex…

Neural and Evolutionary Computing · Computer Science 2024-12-31 Shanqing Yu , Meng Zhou , Jintao Zhou , Minghao Zhao , Yidan Song , Yao Lu , Zeyu Wang , Qi Xuan

The ever-growing popularity and rapid improving of artificial intelligence (AI) have raised rethinking on the evolution of wireless networks. Mobile edge computing (MEC) provides a natural platform for AI applications since it is with rich…

Information Theory · Computer Science 2020-12-29 Shanfeng Huang , Shuai Wang , Rui Wang , Miaowen Wen , Kaibin Huang

The reconfigurable intelligent surface is an emerging technology for wireless communications. We model it as an inhomogeneous boundary of surface impedance, and consider various optimization problems that offer different tradeoffs in terms…

Information Theory · Computer Science 2024-09-27 M. W. Shabir , M. Di Renzo , A. Zappone , M. Debbah