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We here present SIMLR (Single-cell Interpretation via Multi-kernel LeaRning), an open-source tool that implements a novel framework to learn a sample-to-sample similarity measure from expression data observed for heterogenous samples. SIMLR…

Genomics · Quantitative Biology 2018-01-22 Bo Wang , Daniele Ramazzotti , Luca De Sano , Junjie Zhu , Emma Pierson , Serafim Batzoglou

Scalable and efficient processing of genome sequence data, i.e. for variant discovery, is key to the mainstream adoption of High Throughput technology for disease prevention and for clinical use. Achieving scalability, however, requires a…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-06-05 Nicholas Tucci , Jacek Cala , Jannetta Steyn , Paolo Missier

In this short paper, we introduce the Ridgeline model, an extension of the Roofline model [4] for distributed systems. The Roofline model targets shared memory systems, bounding the performance of a kernel based on its operational…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-18 Fabio Checconi , Jesmin Jahan Tithi , Fabrizio Petrini

In this work we propose R-GPM, a parallel computing framework for graph pattern mining (GPM) through a user-defined subgraph relation. More specifically, we enable the computation of statistics of patterns through their subgraph classes,…

Machine Learning · Computer Science 2020-10-13 Carlos H. C. Teixeira , Leonardo Cotta , Bruno Ribeiro , Wagner Meira

Collaborative machine learning (CML) techniques, such as federated learning, have been proposed to train deep learning models across multiple mobile devices and a server. CML techniques are privacy-preserving as a local model that is…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-26 Zihan Zhang , Philip Rodgers , Peter Kilpatrick , Ivor Spence , Blesson Varghese

GitHub projects can be easily replicated through the site's fork process or through a Git clone-push sequence. This is a problem for empirical software engineering, because it can lead to skewed results or mistrained machine learning…

Software Engineering · Computer Science 2023-12-05 Diomidis Spinellis , Zoe Kotti , Audris Mockus

Crowdsourcing and data mining can be used to effectively reduce the effort associated with the partial replication and enhancement of qualitative studies. For example, in a primary study, other researchers explored factors influencing the…

Software Engineering · Computer Science 2019-02-13 Di Chen , Kathyrn Stolee , Tim Menzies

We present Simitate --- a hybrid benchmarking suite targeting the evaluation of approaches for imitation learning. A dataset containing 1938 sequences where humans perform daily activities in a realistic environment is presented. The…

Machine Learning · Computer Science 2019-05-16 Raphael Memmesheimer , Ivanna Mykhalchyshyna , Viktor Seib , Dietrich Paulus

AutoML systems build machine learning models automatically by performing a search over valid data transformations and learners, along with hyper-parameter optimization for each learner. Many AutoML systems use meta-learning to guide search…

Machine Learning · Computer Science 2022-07-18 Mossad Helali , Essam Mansour , Ibrahim Abdelaziz , Julian Dolby , Kavitha Srinivas

Recent work showed that compiling functional programs to use dense, serialized memory representations for recursive algebraic datatypes can yield significant constant-factor speedups for sequential programs. But serializing data in a…

Programming Languages · Computer Science 2021-07-02 Chaitanya Koparkar , Mike Rainey , Michael Vollmer , Milind Kulkarni , Ryan R. Newton

Effective data imputation demands rich latent ``structure" discovery capabilities from ``plain" tabular data. Recent advances in graph neural networks-based data imputation solutions show their strong structure learning potential by…

Machine Learning · Computer Science 2024-04-16 Jiajun Zhong , Weiwei Ye , Ning Gui

Data scientists develop ML pipelines in an iterative manner: they repeatedly screen a pipeline for potential issues, debug it, and then revise and improve its code according to their findings. However, this manual process is tedious and…

Databases · Computer Science 2024-05-01 Stefan Grafberger , Paul Groth , Sebastian Schelter

The LHCb collaboration is one of the four major experiments at the Large Hadron Collider at CERN. Many petabytes of data are produced by the detectors and Monte-Carlo simulations. The LHCb Grid interware LHCbDIRAC is used to make data…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-12-06 Mikhail Hushchyn , Andrey Ustyuzhanin , Philippe Charpentier , Christophe Haen

The recent success of machine learning (ML) has led to an explosive growth both in terms of new systems and algorithms built in industry and academia, and new applications built by an ever-growing community of data science (DS)…

Modern information retrieval systems often rely on multiple components executed in a pipeline. In a research setting, this can lead to substantial redundant computations (e.g., retrieving the same query multiple times for evaluating…

Information Retrieval · Computer Science 2025-04-15 Sean MacAvaney , Craig Macdonald

This paper discusses the latest generation of the MONARC (MOdels of Networked Analysis at Regional Centers) simulation framework, as a design and modeling tool for large scale distributed systems applied to HEP experiments. The simulation…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-06-28 Iosif Legrand , Ciprian Dobre , Ramiro Voicu , Corina Stratan , Catalin Cirstoiu , Lucian Musat

As large language models (LLMs) like ChatGPT become increasingly integrated into our everyday lives--from customer service and education to creative work and personal productivity--understanding how people interact with these AI systems has…

Human-Computer Interaction · Computer Science 2025-03-25 Jin Kim

In many real-world applications data come as discrete metric spaces sampled around 1-dimensional filamentary structures that can be seen as metric graphs. In this paper we address the metric reconstruction problem of such filamentary…

Computational Geometry · Computer Science 2013-05-07 Frédéric Chazal , Jian Sun

Compilers are essential for the performance and correct execution of software and hold universal relevance across various scientific disciplines. Despite this, there is a notable lack of tools for testing and evaluating them, especially…

Programming Languages · Computer Science 2026-01-06 Berke Ates , Filip Dobrosavljević , Theodoros Theodoridis , Zhendong Su

Machine Learning (ML) techniques are indispensable in a wide range of fields. Unfortunately, the exponential increase of dataset sizes are rapidly extending the runtime of sequential algorithms and threatening to slow future progress in ML.…

Machine Learning · Computer Science 2011-07-06 Yucheng Low , Joseph Gonzalez , Aapo Kyrola , Danny Bickson , Carlos Guestrin