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Ordinal variables, such as on the Likert scale, are common in applied research. Yet, existing methods for causal inference tend to target nominal or continuous data. When applied to ordinal data, this fails to account for the inherent…

Methodology · Statistics 2025-02-26 Martina Scauda , Jack Kuipers , Giusi Moffa

We study the problem of efficiently estimating the effect of an intervention on a single variable (atomic interventions) using observational samples in a causal Bayesian network. Our goal is to give algorithms that are efficient in both…

Machine Learning · Computer Science 2020-08-07 Arnab Bhattacharyya , Sutanu Gayen , Saravanan Kandasamy , Ashwin Maran , N. V. Vinodchandran

Observational causal discovery is only identifiable up to the Markov equivalence class. While interventions can reduce this ambiguity, in practice interventions are often soft with multiple unknown targets. In many realistic scenarios, only…

Machine Learning · Statistics 2026-03-05 Mingxuan Zhang , Khushi Desai , Sopho Kevlishvili , Elham Azizi

Identifying variables responsible for changes to a biological system enables applications in drug target discovery and cell engineering. Given a pair of observational and interventional datasets, the goal is to isolate the subset of…

Machine Learning · Computer Science 2025-06-02 Menghua Wu , Umesh Padia , Sean H. Murphy , Regina Barzilay , Tommi Jaakkola

Causal disentanglement aims to uncover a representation of data using latent variables that are interrelated through a causal model. Such a representation is identifiable if the latent model that explains the data is unique. In this paper,…

Promising results have driven a recent surge of interest in continuous optimization methods for Bayesian network structure learning from observational data. However, there are theoretical limitations on the identifiability of underlying…

We consider the problem of learning causal DAGs in the setting where both observational and interventional data is available. This setting is common in biology, where gene regulatory networks can be intervened on using chemical reagents or…

Methodology · Statistics 2019-02-08 Karren D. Yang , Abigail Katcoff , Caroline Uhler

This paper studies the causal representation learning problem when the latent causal variables are observed indirectly through an unknown linear transformation. The objectives are: (i) recovering the unknown linear transformation (up to…

Machine Learning · Statistics 2023-05-02 Burak Varici , Emre Acarturk , Karthikeyan Shanmugam , Abhishek Kumar , Ali Tajer

This paper considers the problem of estimating the unknown intervention targets in a causal directed acyclic graph from observational and interventional data. The focus is on soft interventions in linear structural equation models (SEMs).…

Methodology · Statistics 2021-11-16 Burak Varici , Karthikeyan Shanmugam , Prasanna Sattigeri , Ali Tajer

We consider the problem of recovering the causal structure underlying observations from different experimental conditions when the targets of the interventions in each experiment are unknown. We assume a linear structural causal model with…

Methodology · Statistics 2025-03-13 Juan L. Gamella , Armeen Taeb , Christina Heinze-Deml , Peter Bühlmann

In longitudinal studies where units are embedded in space or a social network, interference may arise, meaning that a unit's outcome can depend on treatment histories of others. The presence of interference poses significant challenges for…

Methodology · Statistics 2025-08-26 Ye Wang , Michael Jetsupphasuk

Causal interactions among a group of variables are often modeled by a single causal graph. In some domains, however, these interactions are best described by multiple co-existing causal graphs, e.g., in dynamical systems or genomics. This…

Machine Learning · Computer Science 2024-12-04 Burak Varıcı , Dmitriy Katz-Rogozhnikov , Dennis Wei , Prasanna Sattigeri , Ali Tajer

In this paper, we deal with the problem of estimating the intervention effect in the statistical causal analysis using the structural equation model and the causal diagram. The intervention effect is defined as a causal effect on the…

Methodology · Statistics 2019-01-17 Shunsuke Horii , Tota Suko

Inferring causal structures from experimentation is a central task in many domains. For example, in biology, recent advances allow us to obtain single-cell expression data under multiple interventions such as drugs or gene knockouts.…

Machine Learning · Computer Science 2023-02-24 Alexander Hägele , Jonas Rothfuss , Lars Lorch , Vignesh Ram Somnath , Bernhard Schölkopf , Andreas Krause

New biological assays like Perturb-seq link highly parallel CRISPR interventions to a high-dimensional transcriptomic readout, providing insight into gene regulatory networks. Causal gene regulatory networks can be represented by directed…

Machine Learning · Statistics 2024-02-22 Albert Xue , Jingyou Rao , Sriram Sankararaman , Harold Pimentel

Interventional causal discovery seeks to identify causal relations by leveraging distributional changes introduced by interventions, even in the presence of latent confounders. Beyond the spurious dependencies induced by latent confounders,…

Machine Learning · Computer Science 2026-02-26 Gongxu Luo , Loka Li , Guangyi Chen , Haoyue Dai , Kun Zhang

Inferring the causal structure of a system typically requires interventional data, rather than just observational data. Since interventional experiments can be costly, it is preferable to select interventions that yield the maximum amount…

Methodology · Statistics 2021-03-30 Michele Zemplenyi , Jeffrey W. Miller

Learning causal relationships between variables is a fundamental task in causal inference and directed acyclic graphs (DAGs) are a popular choice to represent the causal relationships. As one can recover a causal graph only up to its Markov…

Machine Learning · Computer Science 2024-02-14 Davin Choo , Kirankumar Shiragur

Structural learning of directed acyclic graphs (DAGs) or Bayesian networks has been studied extensively under the assumption that data are independent. We propose a new Gaussian DAG model for dependent data which assumes the observations…

Machine Learning · Statistics 2021-07-30 Hangjian Li , Oscar Hernan Madrid Padilla , Qing Zhou

Probabilistic Graphical Bayesian models of causation have continued to impact on strategic analyses designed to help evaluate the efficacy of different interventions on systems. However, the standard causal algebras upon which these…