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Based on the data of the NIH-funded Human Connectome Project, we have computed structural connectomes of 426 human subjects in five different resolutions of 83, 129, 234, 463 and 1015 nodes and several edge weights. The graphs are given in…

Neurons and Cognition · Quantitative Biology 2016-10-07 Csaba Kerepesi , Balazs Szalkai , Balint Varga , Vince Grolmusz

Mapping of human brain structural connectomes via diffusion MRI offers a unique opportunity to understand brain structural connectivity and relate it to various human traits, such as cognition. However, head displacement during image…

Neurons and Cognition · Quantitative Biology 2024-09-13 Yizi Zhang , Meimei Liu , Zhengwu Zhang , David Dunson

BrainPainter is a software for the 3D visualization of human brain structures; it generates colored brain images using user-defined biomarker data for each brain region. However, BrainPainter is only able to generate human brain images. In…

Graphics · Computer Science 2021-03-30 Vedvayas Mallela , Polina Golland , Razvan V. Marinescu

Graphs are quickly emerging as a leading abstraction for the representation of data. One important application domain originates from an emerging discipline called "connectomics". Connectomics studies the brain as a graph; vertices…

Human braingraphs or connectomes are widely studied in the last decade to understand the structural and functional properties of our brain. In the last several years our research group has computed and deposited thousands of human…

Neurons and Cognition · Quantitative Biology 2024-12-03 Balint Varga , Vince Grolmusz

The brain structural connectome is generated by a collection of white matter fiber bundles constructed from diffusion weighted MRI (dMRI), acting as highways for neural activity. There has been abundant interest in studying how the…

Methodology · Statistics 2022-11-03 Didong Li , Phuc Nguyen , Zhengwu Zhang , David B Dunson

Brain networks are typically represented by adjacency matrices, where each node corresponds to a brain region. In traditional brain network analysis, nodes are assumed to be matched across individuals, but the methods used for node matching…

Methodology · Statistics 2025-03-21 Martin Cole , Yang Xiang , Will Consagra , Anuj Srivastava , Xing Qiu , Zhengwu Zhang

The brain's intricate connectome, a blueprint for its function, presents immense complexity, yet it arises from a compact genetic code, hinting at underlying low-dimensional organizational principles. This work bridges connectomics and…

Artificial Intelligence · Computer Science 2025-05-28 Yubin Li , Xingyu Liu , Guozhang Chen

Functional connectomes capture brain interactions via synchronized fluctuations in the functional magnetic resonance imaging signal. If measured during rest, they map the intrinsic functional architecture of the brain. With task-driven…

Neurons and Cognition · Quantitative Biology 2013-04-16 Gaël Varoquaux , R. C. Craddock

The connectomes of different human brains are pairwise distinct: we cannot talk about an abstract "graph of the brain". Two typical connectomes, however, have quite a few common graph edges that may describe the same connections between the…

Neurons and Cognition · Quantitative Biology 2015-01-07 Balazs Szalkai , Csaba Kerepesi , Balint Varga , Vince Grolmusz

Scientists often explore and analyze large-scale scientific simulation data by leveraging two- and three-dimensional visualizations. The data and tasks can be complex and therefore best supported using myriad display technologies, from…

Human-Computer Interaction · Computer Science 2024-04-30 Thomas Marrinan , Madeleine Moeller , Alina Kanayinkal , Victor A. Mateevitsi , Michael E. Papka

Databases of directed- and weighted- connectivity for mouse, macaque and marmoset monkeys, have recently become available and begun to be used to build dynamical models. A hierarchical organization can be defined based on laminar patterns…

Neurons and Cognition · Quantitative Biology 2020-08-11 Xiao-Jing Wang , Ulises Pereira , Marcello G. P. Rosa , Henry Kennedy

Biological neural networks define the brain function and intelligence of humans and other mammals, and form ultra-large, spatial, structured graphs. Their neuronal organization is closely interconnected with the spatial organization of the…

This paper considers the problem of brain disease classification based on connectome data. A connectome is a network representation of a human brain. The typical connectome classification problem is very challenging because of the small…

Machine Learning · Statistics 2020-01-24 Nikita Mokrov , Maxim Panov , Boris A. Gutman , Joshua I. Faskowitz , Neda Jahanshad , Paul M. Thompson

The field of computational modeling of the brain is advancing so rapidly that now it is possible to model large scale networks representing different brain regions with a high level of biological detail in terms of numbers and synapses. For…

This manuscript presents a novel, tightly integrated pipeline for estimating a connectome, which is a comprehensive description of the neural circuits in the brain. The pipeline utilizes magnetic resonance imaging (MRI) data to produce a…

Neurons and Cognition · Quantitative Biology 2011-11-14 William R. Gray , John A. Bogovic , Joshua T. Vogelstein , Bennett A. Landman , Jerry L. Prince , R. Jacob Vogelstein

Brain networks characterize complex connectivities among brain regions as graph structures, which provide a powerful means to study brain connectomes. In recent years, graph neural networks have emerged as a prevalent paradigm of learning…

Machine Learning · Computer Science 2022-06-10 Yi Yang , Yanqiao Zhu , Hejie Cui , Xuan Kan , Lifang He , Ying Guo , Carl Yang

The human connectome has been widely studied over the past decade. A principal finding is that it can be decomposed into communities of densely interconnected brain regions. This result, however, may be limited methodologically. Past…

In brain connectomics, the cortical surface is parcellated into different regions of interest (ROIs) prior to statistical analysis. The brain connectome for each individual can then be represented as a graph, with the nodes corresponding to…

Methodology · Statistics 2020-10-07 Steven Winter , Zhengwu Zhang , David Dunson